(17 nodes) Cyclic nucleotide-binding, conserved site network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Y1Q_0006258	Cyclic nucleotide-binding domain-containing protein. (673 aa)
	PRKG1-2	Uncharacterized protein; Belongs to the protein kinase superfamily. (494 aa)
	HCN1	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (794 aa)
	CNGA2	Cyclic nucleotide-gated olfactory channel. (1430 aa)
	CNGB1	Cyclic nucleotide-gated cation channel beta-1 isoform A. (589 aa)
	PRKAR2A	cAMP-dependent protein kinase type II-alpha regulatory subunit. (355 aa)
	PRKACA	cGMP-dependent protein kinase. (667 aa)
	HCN1-2	Cyclic nucleotide-binding domain-containing protein. (507 aa)
	HCN3	Cyclic nucleotide-binding domain-containing protein. (628 aa)
	Y1Q_0003649	Cyclic nucleotide-binding domain-containing protein. (1366 aa)
	PRKG2	cGMP-dependent protein kinase 2. (831 aa)
	CNGA1	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family. (839 aa)
	HCN4	Cyclic nucleotide-binding domain-containing protein. (770 aa)
	PRKAR1B	Uncharacterized protein. (413 aa)
	PRKAR1A	cAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)
	CNGA2-2	Cyclic nucleotide-binding domain-containing protein. (717 aa)
	PRKAR2B	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B. (408 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA1	CNGA2-2	A0A151MLB5	A0A151NMR9	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	Cyclic nucleotide-binding domain-containing protein.	0.885
CNGA1	CNGB1	A0A151MLB5	A0A151PHE7	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	Cyclic nucleotide-gated cation channel beta-1 isoform A.	0.900
CNGA1	Y1Q_0003649	A0A151MLB5	A0A151MSJ1	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	Cyclic nucleotide-binding domain-containing protein.	0.880
CNGA2-2	CNGA1	A0A151NMR9	A0A151MLB5	Cyclic nucleotide-binding domain-containing protein.	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	0.885
CNGA2-2	CNGB1	A0A151NMR9	A0A151PHE7	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-gated cation channel beta-1 isoform A.	0.878
CNGA2-2	Y1Q_0003649	A0A151NMR9	A0A151MSJ1	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.876
CNGA2-2	Y1Q_0006258	A0A151NMR9	A0A151NX28	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.413
CNGB1	CNGA1	A0A151PHE7	A0A151MLB5	Cyclic nucleotide-gated cation channel beta-1 isoform A.	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	0.900
CNGB1	CNGA2-2	A0A151PHE7	A0A151NMR9	Cyclic nucleotide-gated cation channel beta-1 isoform A.	Cyclic nucleotide-binding domain-containing protein.	0.878
CNGB1	Y1Q_0006258	A0A151PHE7	A0A151NX28	Cyclic nucleotide-gated cation channel beta-1 isoform A.	Cyclic nucleotide-binding domain-containing protein.	0.827
PRKACA	PRKG1-2	A0A151N0U3	A0A151P0E6	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.903
PRKACA	PRKG2	A0A151N0U3	A0A151MPV1	cGMP-dependent protein kinase.	cGMP-dependent protein kinase 2.	0.902
PRKAR1A	PRKAR1B	A0A151N2J0	A0A151N1Z1	cAMP-dependent protein kinase type I-alpha regulatory subunit.	Uncharacterized protein.	0.900
PRKAR1A	PRKAR2A	A0A151N2J0	A0A151MKS7	cAMP-dependent protein kinase type I-alpha regulatory subunit.	cAMP-dependent protein kinase type II-alpha regulatory subunit.	0.904
PRKAR1A	PRKAR2B	A0A151N2J0	A0A151NPC1	cAMP-dependent protein kinase type I-alpha regulatory subunit.	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B.	0.904
PRKAR1B	PRKAR1A	A0A151N1Z1	A0A151N2J0	Uncharacterized protein.	cAMP-dependent protein kinase type I-alpha regulatory subunit.	0.900
PRKAR1B	PRKAR2A	A0A151N1Z1	A0A151MKS7	Uncharacterized protein.	cAMP-dependent protein kinase type II-alpha regulatory subunit.	0.904
PRKAR1B	PRKAR2B	A0A151N1Z1	A0A151NPC1	Uncharacterized protein.	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B.	0.904
PRKAR2A	PRKAR1A	A0A151MKS7	A0A151N2J0	cAMP-dependent protein kinase type II-alpha regulatory subunit.	cAMP-dependent protein kinase type I-alpha regulatory subunit.	0.904
PRKAR2A	PRKAR1B	A0A151MKS7	A0A151N1Z1	cAMP-dependent protein kinase type II-alpha regulatory subunit.	Uncharacterized protein.	0.904