(42 nodes) Cyclic nucleotide-binding domain superfamily network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BVES	Blood vessel epicardial substance isoform A. (448 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (873 aa)
	Y1Q_0011506	Rap guanine nucleotide exchange factor 4-like. (169 aa)
	HCN1	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (794 aa)
	KCNH3	Potassium voltage-gated channel subfamily H member 3. (686 aa)
	KCNH1	Potassium voltage-gated channel subfamily H member 1. (959 aa)
	Y1Q_0021608	Cyclic nucleotide-binding domain-containing protein. (327 aa)
	CNGA2	Cyclic nucleotide-gated olfactory channel. (1430 aa)
	RAPGEF2-2	Uncharacterized protein. (1669 aa)
	KCNH4	Potassium voltage-gated channel subfamily H member 4 isoform B. (1239 aa)
	KCNH8	Potassium voltage-gated channel subfamily H member 8 isoform A. (1163 aa)
	CNBD1	Cyclic nucleotide-binding domain-containing protein 1 isoform A. (387 aa)
	CNGB1	Cyclic nucleotide-gated cation channel beta-1 isoform A. (589 aa)
	HCN3	Cyclic nucleotide-binding domain-containing protein. (628 aa)
	Y1Q_0003649	Cyclic nucleotide-binding domain-containing protein. (1366 aa)
	KCNH8-2	Uncharacterized protein. (816 aa)
	PRKG2	cGMP-dependent protein kinase 2. (831 aa)
	CNGA1	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family. (839 aa)
	HCN4	Cyclic nucleotide-binding domain-containing protein. (770 aa)
	PRKAR2A	cAMP-dependent protein kinase type II-alpha regulatory subunit. (355 aa)
	Y1Q_0023772	Uncharacterized protein. (599 aa)
	POPDC3	Popeye domain-containing protein 3. (161 aa)
	PNPLA7-2	Uncharacterized protein. (1361 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2 isoform A. (1655 aa)
	RAPGEF3	Uncharacterized protein. (874 aa)
	KCNH5	Uncharacterized protein. (989 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2 isoform B. (1103 aa)
	Y1Q_0005328	Cyclic nucleotide-binding domain-containing protein. (578 aa)
	PNPLA7	Patatin-like phospholipase domain-containing protein 7 isoform C. (1303 aa)
	HCN1-2	Cyclic nucleotide-binding domain-containing protein. (507 aa)
	KCNH2-2	Cyclic nucleotide-binding domain-containing protein. (1019 aa)
	PRKACA	cGMP-dependent protein kinase. (667 aa)
	PRKAR1B	Uncharacterized protein. (413 aa)
	PRKAR1A	cAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)
	CNBD2-1	Cyclic nucleotide-binding domain-containing protein 2 isoform B. (591 aa)
	CNGA2-2	Cyclic nucleotide-binding domain-containing protein. (717 aa)
	PRKAR2B	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B. (408 aa)
	CNNM4	Metal transporter CNNM4 isoform A. (557 aa)
	Y1Q_0006258	Cyclic nucleotide-binding domain-containing protein. (673 aa)
	SLC9C2	Sodium/hydrogen exchanger 11. (1175 aa)
	PRKG1-2	Uncharacterized protein; Belongs to the protein kinase superfamily. (494 aa)
	PRKG1	cGMP-dependent protein kinase 1 isoform B. (207 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA1	CNGA2-2	A0A151MLB5	A0A151NMR9	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	Cyclic nucleotide-binding domain-containing protein.	0.885
CNGA1	CNGB1	A0A151MLB5	A0A151PHE7	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	Cyclic nucleotide-gated cation channel beta-1 isoform A.	0.900
CNGA1	Y1Q_0003649	A0A151MLB5	A0A151MSJ1	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	Cyclic nucleotide-binding domain-containing protein.	0.880
CNGA2-2	CNGA1	A0A151NMR9	A0A151MLB5	Cyclic nucleotide-binding domain-containing protein.	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	0.885
CNGA2-2	CNGB1	A0A151NMR9	A0A151PHE7	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-gated cation channel beta-1 isoform A.	0.878
CNGA2-2	Y1Q_0003649	A0A151NMR9	A0A151MSJ1	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.876
CNGA2-2	Y1Q_0006258	A0A151NMR9	A0A151NX28	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.413
CNGB1	CNGA1	A0A151PHE7	A0A151MLB5	Cyclic nucleotide-gated cation channel beta-1 isoform A.	cGMP-gated cation channel alpha-1; Belongs to the G-protein coupled receptor 1 family.	0.900
CNGB1	CNGA2-2	A0A151PHE7	A0A151NMR9	Cyclic nucleotide-gated cation channel beta-1 isoform A.	Cyclic nucleotide-binding domain-containing protein.	0.878
CNGB1	Y1Q_0006258	A0A151PHE7	A0A151NX28	Cyclic nucleotide-gated cation channel beta-1 isoform A.	Cyclic nucleotide-binding domain-containing protein.	0.827
PNPLA7	PNPLA7-2	A0A151MW10	A0A151MEZ2	Patatin-like phospholipase domain-containing protein 7 isoform C.	Uncharacterized protein.	0.901
PNPLA7-2	PNPLA7	A0A151MEZ2	A0A151MW10	Uncharacterized protein.	Patatin-like phospholipase domain-containing protein 7 isoform C.	0.901
PRKACA	PRKG1-2	A0A151N0U3	A0A151P0E6	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.903
PRKACA	PRKG2	A0A151N0U3	A0A151MPV1	cGMP-dependent protein kinase.	cGMP-dependent protein kinase 2.	0.902
PRKAR1A	PRKAR1B	A0A151N2J0	A0A151N1Z1	cAMP-dependent protein kinase type I-alpha regulatory subunit.	Uncharacterized protein.	0.900
PRKAR1A	PRKAR2A	A0A151N2J0	A0A151MKS7	cAMP-dependent protein kinase type I-alpha regulatory subunit.	cAMP-dependent protein kinase type II-alpha regulatory subunit.	0.904
PRKAR1A	PRKAR2B	A0A151N2J0	A0A151NPC1	cAMP-dependent protein kinase type I-alpha regulatory subunit.	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B.	0.904
PRKAR1B	PRKAR1A	A0A151N1Z1	A0A151N2J0	Uncharacterized protein.	cAMP-dependent protein kinase type I-alpha regulatory subunit.	0.900
PRKAR1B	PRKAR2A	A0A151N1Z1	A0A151MKS7	Uncharacterized protein.	cAMP-dependent protein kinase type II-alpha regulatory subunit.	0.904
PRKAR1B	PRKAR2B	A0A151N1Z1	A0A151NPC1	Uncharacterized protein.	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B.	0.904