STRINGSTRING
WWP1 WWP1 NEDD4L NEDD4L NEDD4L-2 NEDD4L-2 SMURF1 SMURF1 SMURF2 SMURF2 ITCH ITCH ITCH-2 ITCH-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WWP1E3 ubiquitin-protein ligase. (946 aa)
NEDD4LE3 ubiquitin-protein ligase. (887 aa)
NEDD4L-2Uncharacterized protein. (1002 aa)
SMURF1E3 ubiquitin-protein ligase. (732 aa)
SMURF2E3 ubiquitin-protein ligase. (786 aa)
ITCHE3 ubiquitin-protein ligase. (894 aa)
ITCH-2E3 ubiquitin-protein ligase. (832 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.