(7 nodes) RyR/IP3 receptor binding core, RIH domain superfamily network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RYR3	Ryanodine receptor 3 isoform E. (4559 aa)
	RYR1	Uncharacterized protein. (2254 aa)
	ITPR3	Uncharacterized protein. (2667 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (1680 aa)
	RYR2	Uncharacterized protein. (5012 aa)
	ITPR2-2	Uncharacterized protein. (2702 aa)
	Y1Q_0023796	Uncharacterized protein. (1088 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ITPR2	ITPR2-2	A0A151MK79	A0A151MPL6	Inositol 1,4,5-trisphosphate receptor type 2.	Uncharacterized protein.	0.901
ITPR2	ITPR3	A0A151MK79	A0A151P4X0	Inositol 1,4,5-trisphosphate receptor type 2.	Uncharacterized protein.	0.903
ITPR2	Y1Q_0023796	A0A151MK79	A0A151MKE7	Inositol 1,4,5-trisphosphate receptor type 2.	Uncharacterized protein.	0.949
ITPR2-2	ITPR2	A0A151MPL6	A0A151MK79	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type 2.	0.901
ITPR2-2	ITPR3	A0A151MPL6	A0A151P4X0	Uncharacterized protein.	Uncharacterized protein.	0.902
ITPR3	ITPR2	A0A151P4X0	A0A151MK79	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type 2.	0.903
ITPR3	ITPR2-2	A0A151P4X0	A0A151MPL6	Uncharacterized protein.	Uncharacterized protein.	0.902
RYR1	RYR2	A0A151P4W6	A0A151M2U5	Uncharacterized protein.	Uncharacterized protein.	0.903
RYR2	RYR1	A0A151M2U5	A0A151P4W6	Uncharacterized protein.	Uncharacterized protein.	0.903
Y1Q_0023796	ITPR2	A0A151MKE7	A0A151MK79	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type 2.	0.949