47 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Y1Q_0000842	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (917 aa)
	SPATA5L1	Spermatogenesis-associated protein 5-like protein 1. (763 aa)
	PCLAF	PCNA-associated factor. (121 aa)
	POLE3	DNA polymerase epsilon subunit 3. (143 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	RCBTB1	RCC1 and BTB domain-containing protein 1. (566 aa)
	POLH	DNA polymerase eta. (707 aa)
	RCBTB1-2	BTB domain-containing protein. (595 aa)
	REV3L	DNA polymerase. (1917 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RPA3	Replication protein A subunit. (120 aa)
	POLD4	DNA polymerase delta subunit 4 isoform A. (206 aa)
	POLI	DNA polymerase iota isoform A. (755 aa)
	MEIOB	Meiosis-specific with OB domain-containing protein isoform A. (516 aa)
	TRIM25-1	E3 ubiquitin/ISG15 ligase TRIM25 isoform B. (640 aa)
	ATAD5	ATPase family AAA domain-containing protein 5. (1673 aa)
	RNF135	E3 ubiquitin-protein ligase RNF135. (457 aa)
	TRIM47	Tripartite motif-containing protein 47. (501 aa)
	MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B. (228 aa)
	RFC5	Replication factor C subunit 5. (336 aa)
	RCHY1	RING finger and CHY zinc finger domain-containing protein 1. (210 aa)
	RFC2	Replication factor C subunit 2. (340 aa)
	Y1Q_0008724	Uncharacterized protein. (128 aa)
	Y1Q_0000841	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (311 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1114 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase. (665 aa)
	UFD1L	Ubiquitin fusion degradation 1-like protein. (307 aa)
	SCARB1	Scavenger receptor class B member 1 isoform A. (959 aa)
	VCP	Uncharacterized protein; Belongs to the AAA ATPase family. (880 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	USP43	Ubiquitin carboxyl-terminal hydrolase 43; Belongs to the peptidase C19 family. (1050 aa)
	USP31	USP domain-containing protein; Belongs to the peptidase C19 family. (1141 aa)
	POLD2	DNA polymerase delta subunit 2. (501 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1160 aa)
	Y1Q_0006787	DNA polymerase delta catalytic subunit-like. (198 aa)
	Y1Q_0007595	DNA_pol_B_exo1 domain-containing protein. (86 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	RFC1	Replication factor C subunit 1. (1130 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
	SPATA5	Spermatogenesis-associated protein 5. (871 aa)
	POLK	DNA polymerase kappa isoform A. (651 aa)
	POLD3-1	DNA polymerase delta subunit 3 isoform A. (466 aa)
	POLD1	DNA polymerase. (439 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
	POLD1-2	DNA polymerase delta catalytic subunit. (392 aa)
	SPRTN	SprT-like domain-containing protein Spartan. (495 aa)
	RFC4	Replication factor C subunit 4. (364 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	MAD2L2	A0A151N2M2	A0A151N3V8	ATPase family AAA domain-containing protein 5.	Mitotic spindle assembly checkpoint protein MAD2B.	0.648
ATAD5	MEIOB	A0A151N2M2	A0A151N203	ATPase family AAA domain-containing protein 5.	Meiosis-specific with OB domain-containing protein isoform A.	0.739
ATAD5	PCLAF	A0A151N2M2	A0A151MAD6	ATPase family AAA domain-containing protein 5.	PCNA-associated factor.	0.457
ATAD5	PCNA	A0A151N2M2	A0A151P620	ATPase family AAA domain-containing protein 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.967
ATAD5	POLD1	A0A151N2M2	A0A151PJP4	ATPase family AAA domain-containing protein 5.	DNA polymerase.	0.641
ATAD5	POLD1-2	A0A151N2M2	A0A151LY32	ATPase family AAA domain-containing protein 5.	DNA polymerase delta catalytic subunit.	0.641
ATAD5	POLD2	A0A151N2M2	A0A151NX84	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 2.	0.689
ATAD5	POLD3-1	A0A151N2M2	A0A151PIY9	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 3 isoform A.	0.640
ATAD5	POLD4	A0A151N2M2	A0A151MU84	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 4 isoform A.	0.416
ATAD5	POLE	A0A151N2M2	A0A151NJU7	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.734
ATAD5	POLE2	A0A151N2M2	A0A151PDT5	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.821
ATAD5	POLE3	A0A151N2M2	A0A151MEU2	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon subunit 3.	0.694
ATAD5	POLH	A0A151N2M2	A0A151MHG1	ATPase family AAA domain-containing protein 5.	DNA polymerase eta.	0.652
ATAD5	POLI	A0A151N2M2	A0A151MWQ6	ATPase family AAA domain-containing protein 5.	DNA polymerase iota isoform A.	0.613
ATAD5	POLK	A0A151N2M2	A0A151PHJ7	ATPase family AAA domain-containing protein 5.	DNA polymerase kappa isoform A.	0.646
ATAD5	REV1	A0A151N2M2	A0A151NXA6	ATPase family AAA domain-containing protein 5.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.653
ATAD5	REV3L	A0A151N2M2	A0A151MJL2	ATPase family AAA domain-containing protein 5.	DNA polymerase.	0.755
ATAD5	RFC1	A0A151N2M2	A0A151P9W6	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 1.	0.706
ATAD5	RFC2	A0A151N2M2	A0A151N5C2	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 2.	0.976
ATAD5	RFC3	A0A151N2M2	A0A151MPG1	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 3.	0.985