37 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	DTL	Denticleless protein-like protein isoform B. (745 aa)
	Y1Q_0007595	DNA_pol_B_exo1 domain-containing protein. (86 aa)
	Y1Q_0006787	DNA polymerase delta catalytic subunit-like. (198 aa)
	DDB1	DNA damage-binding protein 1. (1140 aa)
	POLD2	DNA polymerase delta subunit 2. (501 aa)
	CUL4A	CULLIN_2 domain-containing protein; Belongs to the cullin family. (763 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	SCARB1	Scavenger receptor class B member 1 isoform A. (959 aa)
	Y1Q_0015515	Cullin domain-containing protein; Belongs to the cullin family. (160 aa)
	CUL4B	Cullin-4B; Belongs to the cullin family. (614 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1114 aa)
	Y1Q_0000841	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (311 aa)
	Y1Q_0000842	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (917 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase. (798 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (104 aa)
	Y1Q_0008724	Uncharacterized protein. (128 aa)
	RFC2	Replication factor C subunit 2. (340 aa)
	RFC5	Replication factor C subunit 5. (336 aa)
	ATAD5	ATPase family AAA domain-containing protein 5. (1673 aa)
	MEIOB	Meiosis-specific with OB domain-containing protein isoform A. (516 aa)
	POLD4	DNA polymerase delta subunit 4 isoform A. (206 aa)
	RPA3	Replication protein A subunit. (120 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RAD18	E3 ubiquitin-protein ligase RAD18. (512 aa)
	RCBTB1-2	BTB domain-containing protein. (595 aa)
	RCBTB1	RCC1 and BTB domain-containing protein 1. (566 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	POLE3	DNA polymerase epsilon subunit 3. (143 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	POLD1-2	DNA polymerase delta catalytic subunit. (392 aa)
	POLD1	DNA polymerase. (439 aa)
	POLD3-1	DNA polymerase delta subunit 3 isoform A. (466 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
	WDR48	WD repeat-containing protein 48. (677 aa)
	RFC1	Replication factor C subunit 1. (1130 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CUL4A	A0A151N2M2	A0A151NWT0	ATPase family AAA domain-containing protein 5.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.454
ATAD5	CUL4B	A0A151N2M2	A0A151NN33	ATPase family AAA domain-containing protein 5.	Cullin-4B; Belongs to the cullin family.	0.454
ATAD5	DDB1	A0A151N2M2	A0A151NYZ5	ATPase family AAA domain-containing protein 5.	DNA damage-binding protein 1.	0.603
ATAD5	DTL	A0A151N2M2	A0A151P3K9	ATPase family AAA domain-containing protein 5.	Denticleless protein-like protein isoform B.	0.800
ATAD5	MEIOB	A0A151N2M2	A0A151N203	ATPase family AAA domain-containing protein 5.	Meiosis-specific with OB domain-containing protein isoform A.	0.739
ATAD5	PCNA	A0A151N2M2	A0A151P620	ATPase family AAA domain-containing protein 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.967
ATAD5	POLD1	A0A151N2M2	A0A151PJP4	ATPase family AAA domain-containing protein 5.	DNA polymerase.	0.641
ATAD5	POLD1-2	A0A151N2M2	A0A151LY32	ATPase family AAA domain-containing protein 5.	DNA polymerase delta catalytic subunit.	0.641
ATAD5	POLD2	A0A151N2M2	A0A151NX84	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 2.	0.689
ATAD5	POLD3-1	A0A151N2M2	A0A151PIY9	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 3 isoform A.	0.640
ATAD5	POLD4	A0A151N2M2	A0A151MU84	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 4 isoform A.	0.416
ATAD5	POLE	A0A151N2M2	A0A151NJU7	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.734
ATAD5	POLE2	A0A151N2M2	A0A151PDT5	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.821
ATAD5	POLE3	A0A151N2M2	A0A151MEU2	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon subunit 3.	0.694
ATAD5	RAD18	A0A151N2M2	A0A151MK62	ATPase family AAA domain-containing protein 5.	E3 ubiquitin-protein ligase RAD18.	0.820
ATAD5	RFC1	A0A151N2M2	A0A151P9W6	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 1.	0.706
ATAD5	RFC2	A0A151N2M2	A0A151N5C2	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 2.	0.976
ATAD5	RFC3	A0A151N2M2	A0A151MPG1	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 3.	0.985
ATAD5	RFC4	A0A151N2M2	A0A151M684	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 4.	0.982
ATAD5	RFC5	A0A151N2M2	A0A151N4L9	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 5.	0.981