STRINGSTRING
PSMC6 PSMC6 PSMD14 PSMD14 PSMA3 PSMA3 EGLN1 EGLN1 PSMB4 PSMB4 PSMD4 PSMD4 HYKK HYKK PSMC3 PSMC3 PSMA1 PSMA1 PSMD5-1 PSMD5-1 PSMB7 PSMB7 PSMD8 PSMD8 PSME4 PSME4 RPS27A RPS27A PSMD6 PSMD6 VHL VHL Y1Q_0001781 Y1Q_0001781 PSMB8 PSMB8 PSMB9 PSMB9 TCEB1 TCEB1 PSMD1 PSMD1 Y1Q_0005128 Y1Q_0005128 PSMD12 PSMD12 HIF3A-1 HIF3A-1 HIF1A HIF1A WTIP WTIP PSMA5 PSMA5 PSMC5 PSMC5 TCEB2 TCEB2 PSMC4 PSMC4 RBX1 RBX1 PSMA6 PSMA6 EGLN3 EGLN3 PSME2 PSME2 PSME1 PSME1 PSMD10 PSMD10 PSMD7 PSMD7 PSMC2 PSMC2 PSMB11 PSMB11 PSMB5 PSMB5 UBE2D2 UBE2D2 PSMD9-1 PSMD9-1 PSMB6 PSMB6 KXD1 KXD1 EPAS1 EPAS1 PSMD13 PSMD13 PSMA7 PSMA7 UBE2D1 UBE2D1 PSMF1 PSMF1 PSMB2 PSMB2 PSMD3 PSMD3 PSMB3 PSMB3 PSMC1 PSMC1 PSMD11 PSMD11 CUL2 CUL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (460 aa)
PSMA3Proteasome subunit alpha type. (256 aa)
EGLN1Egl nine-like protein 1. (225 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
HYKKProteasome endopeptidase complex. (600 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
PSMD5-126S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
PSMB7Proteasome subunit beta. (274 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (257 aa)
PSME4Proteasome activator complex subunit 4. (1808 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (348 aa)
VHLVon Hippel-Lindau disease tumor suppressor. (174 aa)
Y1Q_0001781Ubiquitin-like domain-containing protein. (121 aa)
PSMB8Proteasome subunit beta. (282 aa)
PSMB9Proteasome subunit beta. (216 aa)
TCEB1Transcription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
Y1Q_0005128Proteasome subunit beta. (277 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (441 aa)
HIF3A-1Hypoxia-inducible factor 3-alpha isoform C. (374 aa)
HIF1AUncharacterized protein. (747 aa)
WTIPWilms tumor protein 1-interacting protein isoform A. (474 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
TCEB2Transcription elongation factor B polypeptide 2. (115 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (104 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
EGLN3Egl nine-like protein 3. (249 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
PSME1Proteasome activator complex subunit 1. (150 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB11Proteasome subunit beta. (261 aa)
PSMB5Proteasome subunit beta type-5. (211 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
PSMD9-126S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
PSMB6Proteasome subunit beta. (227 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
EPAS1Endothelial PAS domain-containing protein 1. (863 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (197 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (521 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (518 aa)
CUL2Cullin-2; Belongs to the cullin family. (720 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (18%) [HD]