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RUFY2 RUFY2 INPP5D INPP5D TMEM55A-1 TMEM55A-1 PIP4K2C PIP4K2C Y1Q_0003612 Y1Q_0003612 PIP4K2A PIP4K2A RUNDC3A RUNDC3A MTMR7 MTMR7 ENPP6 ENPP6 PI4K2B-2 PI4K2B-2 SASH3 SASH3 OCRL-2 OCRL-2 PIP4K2B PIP4K2B MTMR14 MTMR14 Y1Q_0016077 Y1Q_0016077 PITPNB PITPNB FOXP4 FOXP4 MN1 MN1 PIK3R4 PIK3R4 MTM1 MTM1 TNFAIP8L1 TNFAIP8L1 PTPN20 PTPN20 PTEN PTEN Y1Q_0002614 Y1Q_0002614 INPP4A-2 INPP4A-2 MFSD6L MFSD6L PIK3R6 PIK3R6 PIK3R5 PIK3R5 INPP5D-2 INPP5D-2 INPP5F INPP5F PLEKHA1-1 PLEKHA1-1 MTMR4 MTMR4 MTMR11 MTMR11 FAM109A FAM109A PIK3CG PIK3CG Y1Q_0015641 Y1Q_0015641 MTMR8 MTMR8 PTPN13 PTPN13 SAMD5 SAMD5 SASH1 SASH1 PLEKHA4 PLEKHA4 PLEKHA4L PLEKHA4L PLEKHA5 PLEKHA5 PIK3C2G-1 PIK3C2G-1 PIK3C2G-2 PIK3C2G-2 FAM109B FAM109B Y1Q_0003573 Y1Q_0003573 INPP5J INPP5J PIP5K1C PIP5K1C TPTE2 TPTE2 DIA1B DIA1B MFSD6 MFSD6 PIKFYVE PIKFYVE PLEKHM3 PLEKHM3 PIK3R1 PIK3R1 MTMR1 MTMR1 MTM1-2 MTM1-2 GDPD2 GDPD2 GDPD1 GDPD1 Y1Q_0012160 Y1Q_0012160 MTMR3 MTMR3 PI4K2B-1 PI4K2B-1 PIK3CD PIK3CD Y1Q_0008197 Y1Q_0008197 SNX29 SNX29 RUBCN RUBCN PIK3R1-2 PIK3R1-2 MTMR12 MTMR12 PLEKHA2 PLEKHA2 PIK3C3 PIK3C3 PNPLA7 PNPLA7 MTMR9-2 MTMR9-2 VAC14 VAC14 MTMR6 MTMR6 PLEKHA8 PLEKHA8 RUNDC3B RUNDC3B GDPD3 GDPD3 Y1Q_0018542 Y1Q_0018542 MTMR9 MTMR9 PI4KA PI4KA Y1Q_0015746 Y1Q_0015746 PITPNA PITPNA INPP5K INPP5K PLEKHA3 PLEKHA3 MORN2-1 MORN2-1 SYNJ2 SYNJ2 TMEM55B TMEM55B GDPD5 GDPD5 GDPD4 GDPD4 FAM102B FAM102B Y1Q_0012336 Y1Q_0012336 PI4KBL PI4KBL Y1Q_0012343 Y1Q_0012343 TNFAIP8L2 TNFAIP8L2 PIK3CB-2 PIK3CB-2 PIK3CB PIK3CB RUFY1 RUFY1 INPP4A INPP4A TNFAIP8-1 TNFAIP8-1 PIP5K1B PIP5K1B TNFAIP8L3 TNFAIP8L3 MTMR10 MTMR10 PIK3C2B PIK3C2B PLEKHA6 PLEKHA6 PLEKHA7 PLEKHA7 PIK3C2A PIK3C2A INSC INSC SAMSN1-1 SAMSN1-1 SYNJ1 SYNJ1 PNPLA7-2 PNPLA7-2 PIP5KL1 PIP5KL1 FAM102A FAM102A CCDC180 CCDC180 INPP5E INPP5E RAB14 RAB14 FIG4 FIG4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUFY2RUN and FYVE domain-containing protein 2 isoform A. (601 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform A. (1485 aa)
TMEM55A-1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (458 aa)
Y1Q_0003612Rho-GAP domain-containing protein. (189 aa)
PIP4K2APIPK domain-containing protein. (405 aa)
RUNDC3ARUN domain-containing protein 3A isoform B. (441 aa)
MTMR7Uncharacterized protein. (660 aa)
ENPP6Ectonucleotide pyrophosphatase/phosphodiesterase family member 6. (419 aa)
PI4K2B-2Phosphatidylinositol 4-kinase type 2-beta. (458 aa)
SASH3SAM and SH3 domain-containing protein 3. (382 aa)
OCRL-2Rho-GAP domain-containing protein. (931 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (411 aa)
MTMR14Myotubularin-related protein 14. (354 aa)
Y1Q_0016077Uncharacterized protein. (68 aa)
PITPNBPhosphatidylinositol transfer protein beta. (1302 aa)
FOXP4Fork-head domain-containing protein. (617 aa)
MN1Putative tumor suppressor protein MN1. (301 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1397 aa)
MTM1Myotubularin isoform B. (650 aa)
TNFAIP8L1Tumor necrosis factor alpha-induced protein 8-like protein 1. (204 aa)
PTPN20Tyrosine-protein phosphatase non-receptor type 20 isoform A. (2367 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
Y1Q_0002614Pleckstrin-like proteiny domain-containing family A member 3-like. (298 aa)
INPP4A-2C2 domain-containing protein. (967 aa)
MFSD6LMajor facilitator superfamily domain-containing protein 6-like. (497 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6. (754 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5. (886 aa)
INPP5D-2SH2 domain-containing protein. (1209 aa)
INPP5FPhosphatidylinositide phosphatase SAC2. (1108 aa)
PLEKHA1-1Pleckstrin-like proteiny domain-containing family A member 1 isoform B. (358 aa)
MTMR4Myotubularin-related protein 4 isoform A. (1123 aa)
MTMR11Myotubularin-related protein 11. (710 aa)
FAM109ASesquipedalian-1. (319 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (810 aa)
Y1Q_0015641SH2 domain-containing protein. (1113 aa)
MTMR8Myotubularin phosphatase domain-containing protein. (632 aa)
PTPN13Tyrosine-protein phosphatase non-receptor type 13 isoform C. (2492 aa)
SAMD5Sterile alpha motif domain-containing protein 5. (148 aa)
SASH1SAM and SH3 domain-containing protein 1 isoform B. (1296 aa)
PLEKHA4Pleckstrin-like proteiny domain-containing family A member 4. (444 aa)
PLEKHA4LPleckstrin-like proteiny domain-containing family A member 4. (198 aa)
PLEKHA5Pleckstrin-like proteiny domain-containing family A member 5 isoform A. (1108 aa)
PIK3C2G-1Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform C; Belongs to the PI3/PI4-kinase family. (640 aa)
PIK3C2G-2Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (495 aa)
FAM109BSesquipedalian-2. (279 aa)
Y1Q_0003573SH3 domain-containing protein. (167 aa)
INPP5JPhosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform A. (780 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (637 aa)
TPTE2Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (511 aa)
DIA1BDeleted in autism protein 1. (429 aa)
MFSD6Major facilitator superfamily domain-containing protein 6. (706 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform A. (2159 aa)
PLEKHM3Pleckstrin-like proteiny domain-containing family M member 3. (755 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (727 aa)
MTMR1Uncharacterized protein. (655 aa)
MTM1-2Uncharacterized protein. (603 aa)
GDPD2Glycerophosphoinositol inositolphosphodiesterase GDPD2. (523 aa)
GDPD1Glycerophosphodiester phosphodiesterase domain-containing protein 1. (312 aa)
Y1Q_0012160Uncharacterized protein. (611 aa)
MTMR3Uncharacterized protein. (1166 aa)
PI4K2B-1Phosphatidylinositol 4-kinase type 2-beta. (340 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1030 aa)
Y1Q_0008197Uncharacterized protein. (95 aa)
SNX29Sorting nexin-29 isoform A. (880 aa)
RUBCNRun domain Beclin-1 interacting and cysteine-rich containing protein isoform A. (1001 aa)
PIK3R1-2Uncharacterized protein. (750 aa)
MTMR12Myotubularin-related protein 12. (740 aa)
PLEKHA2Pleckstrin-like proteiny domain-containing family A member 2. (482 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
PNPLA7Patatin-like phospholipase domain-containing protein 7 isoform C. (1303 aa)
MTMR9-2Myotubularin phosphatase domain-containing protein. (550 aa)
VAC14VAC14-like protein. (780 aa)
MTMR6Myotubularin-related protein 6. (618 aa)
PLEKHA8Pleckstrin-like proteiny domain-containing family A member 8. (513 aa)
RUNDC3BRUN domain-containing protein 3B isoform C. (543 aa)
GDPD3Glycerophosphodiester phosphodiesterase domain-containing protein 3. (325 aa)
Y1Q_0018542Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (627 aa)
MTMR9Myotubularin-related protein 9 isoform A. (530 aa)
PI4KAPhosphatidylinositol 4-kinase alpha isoform A; Belongs to the PI3/PI4-kinase family. (2120 aa)
Y1Q_0015746Uncharacterized protein. (148 aa)
PITPNAPhosphatidylinositol transfer protein alpha isoform. (272 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform B. (472 aa)
PLEKHA3Pleckstrin-like proteiny domain-containing family A member 3 isoform B. (302 aa)
MORN2-1MORN repeat-containing protein 2 isoform A. (138 aa)
SYNJ2Uncharacterized protein. (1514 aa)
TMEM55BPhosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (208 aa)
GDPD5Glycerophosphodiester phosphodiesterase domain-containing protein 5. (594 aa)
GDPD4Glycerophosphodiester phosphodiesterase domain-containing protein 4. (579 aa)
FAM102BProtein FAM102B. (361 aa)
Y1Q_0012336PIPK domain-containing protein. (608 aa)
PI4KBLPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (1164 aa)
Y1Q_0012343PIK helical domain-containing protein. (438 aa)
TNFAIP8L2Tumor necrosis factor alpha-induced protein 8-like protein 2. (184 aa)
PIK3CB-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1071 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RUFY1RUN and FYVE domain-containing protein 1 isoform B. (655 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase. (1029 aa)
TNFAIP8-1Tumor necrosis factor alpha-induced protein 8 isoform A. (198 aa)
PIP5K1BPIPK domain-containing protein. (618 aa)
TNFAIP8L3Tumor necrosis factor alpha-induced protein 8-like protein 3. (255 aa)
MTMR10Myotubularin-related protein 10. (766 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform B; Belongs to the PI3/PI4-kinase family. (1673 aa)
PLEKHA6Pleckstrin-like proteiny domain-containing family A member 6 isoform D. (1293 aa)
PLEKHA7Pleckstrin-like proteiny domain-containing family A member 7. (1222 aa)
PIK3C2AUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1691 aa)
INSCInscuteable-like protein isoform B. (553 aa)
SAMSN1-1SAM domain-containing protein SAMSN-1 isoform C. (784 aa)
SYNJ1PAX3-and PAX7-binding protein 1. (2276 aa)
PNPLA7-2Uncharacterized protein. (1361 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1. (440 aa)
FAM102AProtein FAM102A. (383 aa)
CCDC180Coiled-coil domain-containing protein 180. (2011 aa)
INPP5EInositol polyphosphate 5-phosphatase. (450 aa)
RAB14Ras-related protein Rab-14. (215 aa)
FIG4Polyphosphoinositide phosphatase. (907 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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