STRINGSTRING
CAV1 CAV1 PTK2B PTK2B SHE SHE PTK2 PTK2 KDR KDR TENM3-2 TENM3-2 VEGFC VEGFC ITGB3-2 ITGB3-2 JUP JUP Y1Q_0017424 Y1Q_0017424 RASA1 RASA1 NRP2 NRP2 ABI2 ABI2 SH2D2A SH2D2A MAPK12 MAPK12 NCKAP1 NCKAP1 AKT3 AKT3 STX7 STX7 PAK2 PAK2 VAV3-2 VAV3-2 TGFB1I1 TGFB1I1 PIK3CB-2 PIK3CB-2 PIK3CB PIK3CB Y1Q_0010680 Y1Q_0010680 FLT1 FLT1 SHF SHF MAPKAPK3 MAPKAPK3 CYFIP1 CYFIP1 NRAS NRAS MAPKAPK3-2 MAPKAPK3-2 VAV2 VAV2 FNDC3A FNDC3A AKT3-2 AKT3-2 FNDC3A-2 FNDC3A-2 VEGFA-1 VEGFA-1 PDPK1 PDPK1 SZRD1-1 SZRD1-1 WASF1 WASF1 PAK2-2 PAK2-2 CAV3 CAV3 CRK CRK PGF-1 PGF-1 Y1Q_0018542 Y1Q_0018542 AXL AXL AKT2 AKT2 Y1Q_0014303 Y1Q_0014303 FLT1-2 FLT1-2 WASF3 WASF3 BCAR1 BCAR1 BRK1 BRK1 C1GALT1A C1GALT1A NCKAP1L NCKAP1L RICTOR RICTOR ELMO3-2 ELMO3-2 CDC42 CDC42 Y1Q_0019633 Y1Q_0019633 FIGF FIGF NEDD9 NEDD9 PXN PXN Y1Q_0018846 Y1Q_0018846 HSPB1 HSPB1 TENM4 TENM4 PRR5 PRR5 CDH5 CDH5 ROCK2 ROCK2 MAPK14 MAPK14 WASF2 WASF2 NRP2-2 NRP2-2 ABI2-2 ABI2-2 ITGAV-2 ITGAV-2 SHB SHB ROCK1 ROCK1 Y1Q_0012304 Y1Q_0012304 ELMO3 ELMO3 NCF4 NCF4 KRAS-2 KRAS-2 PRKACB PRKACB KRAS-1 KRAS-1 Y1Q_0006499 Y1Q_0006499 VAV3 VAV3 TENM3 TENM3 Y1Q_0015577 Y1Q_0015577 Y1Q_0015586 Y1Q_0015586 MAPK11 MAPK11 Y1Q_0015649 Y1Q_0015649 PAK3 PAK3 STX12 STX12 EFS-1 EFS-1 TENM2 TENM2 Y1Q_0004890 Y1Q_0004890 Y1Q_0004891 Y1Q_0004891 ARVCF ARVCF LPXN LPXN CTNND1 CTNND1 RNF222 RNF222 NCK2 NCK2 CYFIP1-2 CYFIP1-2 SHD-2 SHD-2 Y1Q_0006325 Y1Q_0006325 CASS4 CASS4 SHC2 SHC2 CYBA CYBA ELMO1-2 ELMO1-2 CTNNB1 CTNNB1 ELMO1-1 ELMO1-1 BAIAP2 BAIAP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PTK2BUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
SHESH2 domain-containing adapter protein E. (442 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1353 aa)
TENM3-2Uncharacterized protein. (2770 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (414 aa)
ITGB3-2Integrin beta; Belongs to the integrin beta chain family. (783 aa)
JUPUncharacterized protein. (718 aa)
Y1Q_0017424Uncharacterized protein. (235 aa)
RASA1Ras GTPase-activating protein 1. (904 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
ABI2Abl interactor 2. (463 aa)
SH2D2ASH2 domain-containing protein 2A. (469 aa)
MAPK12Mitogen-activated protein kinase. (309 aa)
NCKAP1Uncharacterized protein. (1119 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
STX7Syntaxin-7; Belongs to the syntaxin family. (274 aa)
PAK2Non-specific serine/threonine protein kinase. (546 aa)
VAV3-2Uncharacterized protein. (846 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein. (387 aa)
PIK3CB-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1071 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Y1Q_0010680Uncharacterized protein. (176 aa)
FLT1Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1725 aa)
SHFSH2 domain-containing adapter protein F isoform C. (366 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (354 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
NRASGTPase NRas. (189 aa)
MAPKAPK3-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (387 aa)
VAV2Uncharacterized protein. (839 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1011 aa)
AKT3-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
FNDC3A-2Uncharacterized protein. (1195 aa)
VEGFA-1Vascular endothelial growth factor A isoform A; Belongs to the PDGF/VEGF growth factor family. (216 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (515 aa)
SZRD1-1SUZ domain-containing protein 1 isoform B. (153 aa)
WASF1Wiskott-Aldrich syndrome protein family member 1. (454 aa)
PAK2-2Non-specific serine/threonine protein kinase. (741 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CRKAdapter molecule crk. (291 aa)
PGF-1Placenta growth factor isoform A; Belongs to the PDGF/VEGF growth factor family. (219 aa)
Y1Q_0018542Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (627 aa)
AXLTyrosine-protein kinase receptor UFO isoform B. (557 aa)
AKT2Non-specific serine/threonine protein kinase. (270 aa)
Y1Q_0014303Uncharacterized protein. (358 aa)
FLT1-2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1333 aa)
WASF3Wiskott-Aldrich syndrome protein family member 3 isoform B. (566 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (960 aa)
BRK1Protein BRICK1. (75 aa)
C1GALT1AGlycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A. (432 aa)
NCKAP1LNck-associated protein 1-like. (672 aa)
RICTORRapamycin-insensitive companion of mTOR. (1439 aa)
ELMO3-2ELMO domain-containing protein. (1145 aa)
CDC42Cell division control 42-like protein. (235 aa)
Y1Q_0019633Protein kinase domain-containing protein. (107 aa)
FIGFVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
NEDD9Enhancer of filamentation 1. (802 aa)
PXNPaxillin isoform C. (614 aa)
Y1Q_0018846Uncharacterized protein. (422 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (217 aa)
TENM4Uncharacterized protein. (2883 aa)
PRR5Proline-rich protein 5 isoform B. (468 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (733 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1396 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2. (347 aa)
NRP2-2Neuropilin; Belongs to the neuropilin family. (942 aa)
ABI2-2Uncharacterized protein. (470 aa)
ITGAV-2Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1046 aa)
SHBSH2 domain-containing adapter protein B. (348 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
Y1Q_0012304Uncharacterized protein. (77 aa)
ELMO3Engulfment and cell motility protein 3 isoform A. (673 aa)
NCF4Neutrophil cytosol factor 4. (352 aa)
KRAS-2GTPase KRas. (219 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily. (368 aa)
KRAS-1GTPase KRas. (215 aa)
Y1Q_0006499Uncharacterized protein; Belongs to the protein kinase superfamily. (401 aa)
VAV3Guanine nucleotide exchange factor VAV3. (815 aa)
TENM3Teneurin-3 isoform A. (2705 aa)
Y1Q_0015577Wiskott-Aldrich syndrome protein family member 3-like. (509 aa)
Y1Q_0015586Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1335 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
Y1Q_0015649Uncharacterized protein. (1191 aa)
PAK3Non-specific serine/threonine protein kinase. (526 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (269 aa)
EFS-1Embryonal Fyn-associated substrate isoform A. (392 aa)
TENM2Uncharacterized protein. (2558 aa)
Y1Q_0004890Uncharacterized protein. (67 aa)
Y1Q_0004891Teneurin N-terminal domain-containing protein. (217 aa)
ARVCFUncharacterized protein. (918 aa)
LPXNLeupaxin. (388 aa)
CTNND1Catenin delta-1 isoform B. (996 aa)
RNF222RING finger protein 222. (238 aa)
NCK2Cytoplasmic protein NCK2. (301 aa)
CYFIP1-2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1289 aa)
SHD-2Uncharacterized protein. (137 aa)
Y1Q_0006325Uncharacterized protein. (188 aa)
CASS4Cas scaffolding protein family member 4. (860 aa)
SHC2SHC-transforming protein 2. (550 aa)
CYBACytochrome b-245 light chain. (171 aa)
ELMO1-2Engulfment and cell motility protein 1. (239 aa)
CTNNB1Catenin beta-1 isoform B. (783 aa)
ELMO1-1Engulfment and cell motility protein 1. (519 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform A. (541 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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