73 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC	Adenomatous polyposis coli protein. (2841 aa)
	TCF7L1	Transcription factor 7-like 1 isoform D. (567 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14. (460 aa)
	PSMA3	Proteasome subunit alpha type. (256 aa)
	PPP2R5E	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (515 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
	PSMD4	26S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
	CSNK1A1	Casein kinase I isoform C; Belongs to the protein kinase superfamily. (365 aa)
	PPP2CA	Serine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa)
	TCF7	Transcription factor 7 isoform A. (452 aa)
	TLE1-2	Uncharacterized protein. (780 aa)
	TLE4	Uncharacterized protein. (980 aa)
	TLE1	Transducin-like enhancer protein 1 isoform A. (828 aa)
	HYKK	Proteasome endopeptidase complex. (600 aa)
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
	PSMA1	Proteasome subunit alpha type. (261 aa)
	PPP2R1A	Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa)
	PPP2R5D	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (596 aa)
	GSK3B-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
	PSMD5-1	26S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
	PSMB7	Proteasome subunit beta. (274 aa)
	PSME4	Proteasome activator complex subunit 4. (1808 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	LEF1	Lymphoid enhancer-binding factor 1 isoform B. (391 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6. (348 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform B. (626 aa)
	PSMB8	Proteasome subunit beta. (282 aa)
	PSMB9	Proteasome subunit beta. (216 aa)
	PPP2R5B	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (493 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
	Y1Q_0005128	Proteasome subunit beta. (277 aa)
	PSMD8	26S proteasome non-ATPase regulatory subunit 8. (257 aa)
	GSK3B	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (413 aa)
	PSMD12	26S proteasome non-ATPase regulatory subunit 12. (441 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMC5	Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
	PSMC4	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (104 aa)
	PSMA6	Proteasome subunit alpha type. (252 aa)
	PSME2	Proteasome activator complex subunit 2. (242 aa)
	PSME1	Proteasome activator complex subunit 1. (150 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10. (226 aa)
	AMER1	APC membrane recruitment protein 1. (1161 aa)
	PSMD7	26S proteasome non-ATPase regulatory subunit 7. (322 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	PSMB11	Proteasome subunit beta. (261 aa)
	PSMB5	Proteasome subunit beta type-5. (211 aa)
	PSMD9-1	26S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
	PSMB6	Proteasome subunit beta. (227 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	TCF7L2	Transcription factor 7-like 2 isoform A. (411 aa)
	PSMD13	26S proteasome non-ATPase regulatory subunit 13. (376 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	AES	Amino-terminal enhancer of split. (221 aa)
	Y1Q_0000264	Transducin-like enhancer protein 2. (198 aa)
	Y1Q_0000266	Uncharacterized protein. (595 aa)
	TLE2	WD_REPEATS_REGION domain-containing protein. (436 aa)
	PSMF1	Proteasome inhibitor PI31 subunit. (273 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	CTNNB1	Catenin beta-1 isoform B. (783 aa)
	PPP2R5C	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (479 aa)
	ZRANB1	Ubiquitin thioesterase ZRANB1. (747 aa)
	CTBP2	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (461 aa)
	PSMD3	26S proteasome non-ATPase regulatory subunit 3. (521 aa)
	PSMB3	Proteasome subunit beta. (205 aa)
	PPP2R5C-2	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (602 aa)
	PSMC1	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
	CTBP1-2	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (451 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (518 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
	APC2	Uncharacterized protein. (2467 aa)
	PSMB2	Proteasome subunit beta. (201 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AES	CTNNB1	A0A151P0B8	A0A151P2N9	Amino-terminal enhancer of split.	Catenin beta-1 isoform B.	0.418
AES	LEF1	A0A151P0B8	A0A151MJ72	Amino-terminal enhancer of split.	Lymphoid enhancer-binding factor 1 isoform B.	0.572
AES	TCF7	A0A151P0B8	A0A151M701	Amino-terminal enhancer of split.	Transcription factor 7 isoform A.	0.572
AES	TCF7L1	A0A151P0B8	A0A151LY51	Amino-terminal enhancer of split.	Transcription factor 7-like 1 isoform D.	0.571
AES	TCF7L2	A0A151P0B8	A0A151NUL3	Amino-terminal enhancer of split.	Transcription factor 7-like 2 isoform A.	0.571
AES	TLE2	A0A151P0B8	A0A151P151	Amino-terminal enhancer of split.	WD_REPEATS_REGION domain-containing protein.	0.893
AES	Y1Q_0000266	A0A151P0B8	A0A151P109	Amino-terminal enhancer of split.	Uncharacterized protein.	0.884
AMER1	APC	A0A151NNC1	A0A151PIC9	APC membrane recruitment protein 1.	Adenomatous polyposis coli protein.	0.859
AMER1	APC2	A0A151NNC1	A0A151PFV4	APC membrane recruitment protein 1.	Uncharacterized protein.	0.859
AMER1	BTRC	A0A151NNC1	A0A151MLH5	APC membrane recruitment protein 1.	F-box/WD repeat-containing protein 1A isoform B.	0.703
AMER1	CSNK1A1	A0A151NNC1	A0A151M6R7	APC membrane recruitment protein 1.	Casein kinase I isoform C; Belongs to the protein kinase superfamily.	0.745
AMER1	CTNNB1	A0A151NNC1	A0A151P2N9	APC membrane recruitment protein 1.	Catenin beta-1 isoform B.	0.899
AMER1	CUL1	A0A151NNC1	A0A151P2L7	APC membrane recruitment protein 1.	Cullin-1; Belongs to the cullin family.	0.602
AMER1	GSK3B	A0A151NNC1	A0A151N132	APC membrane recruitment protein 1.	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily.	0.731
AMER1	GSK3B-2	A0A151NNC1	A0A151MD62	APC membrane recruitment protein 1.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.731
AMER1	RBX1	A0A151NNC1	A0A151NHM4	APC membrane recruitment protein 1.	E3 ubiquitin-protein ligase RBX1.	0.598
AMER1	RPS27A	A0A151NNC1	A0A151MGG2	APC membrane recruitment protein 1.	Ubiquitin-40S ribosomal protein S27a.	0.613
APC	AMER1	A0A151PIC9	A0A151NNC1	Adenomatous polyposis coli protein.	APC membrane recruitment protein 1.	0.859
APC	APC2	A0A151PIC9	A0A151PFV4	Adenomatous polyposis coli protein.	Uncharacterized protein.	0.903
APC	BTRC	A0A151PIC9	A0A151MLH5	Adenomatous polyposis coli protein.	F-box/WD repeat-containing protein 1A isoform B.	0.726