STRINGSTRING
CREBBP CREBBP Y1Q_0012805 Y1Q_0012805 Y1Q_0014479 Y1Q_0014479 Y1Q_0018383 Y1Q_0018383 CTNNB1 CTNNB1 BCL9L-1 BCL9L-1 TLE2 TLE2 Y1Q_0000266 Y1Q_0000266 Y1Q_0000264 Y1Q_0000264 AES AES TCF7L2 TCF7L2 Y1Q_0006757 Y1Q_0006757 HIST1H4D HIST1H4D CDC73 CDC73 Y1Q_0016099 Y1Q_0016099 Y1Q_0024039 Y1Q_0024039 CREBBPA CREBBPA TERT TERT ASH2L ASH2L PYGO2 PYGO2 MEN1 MEN1 Y1Q_0009388 Y1Q_0009388 TRRAP TRRAP LEF1 LEF1 BCL9 BCL9 SLC39A13 SLC39A13 RBBP5 RBBP5 PYGO1 PYGO1 LEO1 LEO1 TLE1 TLE1 TLE4 TLE4 TLE1-2 TLE1-2 TCF7 TCF7 HIST1H2BF HIST1H2BF HIST2H2BE HIST2H2BE Y1Q_0020100 Y1Q_0020100 Y1Q_0020098 Y1Q_0020098 TCF7L1 TCF7L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREBBPCREB-binding protein isoform C. (2208 aa)
Y1Q_0012805Histone H2B; Belongs to the histone H2B family. (118 aa)
Y1Q_0014479Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
Y1Q_0018383Histone H2B-like; Belongs to the histone H2B family. (152 aa)
CTNNB1Catenin beta-1 isoform B. (783 aa)
BCL9L-1B-cell CLL/lymphoma 9-like protein isoform B. (1409 aa)
TLE2WD_REPEATS_REGION domain-containing protein. (436 aa)
Y1Q_0000266Uncharacterized protein. (595 aa)
Y1Q_0000264Transducin-like enhancer protein 2. (198 aa)
AESAmino-terminal enhancer of split. (221 aa)
TCF7L2Transcription factor 7-like 2 isoform A. (411 aa)
Y1Q_0006757Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa)
HIST1H4DHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CDC73Parafibromin. (531 aa)
Y1Q_0016099Histone H2B; Belongs to the histone H2B family. (126 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
CREBBPACREB-binding protein isoform A. (1756 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (599 aa)
ASH2LSet1/Ash2 histone methyltransferase complex subunit ASH2. (591 aa)
PYGO2Pygopus-like protein 2. (371 aa)
MEN1Menin. (456 aa)
Y1Q_0009388Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
TRRAPTransformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (3770 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform B. (391 aa)
BCL9B-cell CLL/lymphoma 9 protein. (1427 aa)
SLC39A13Zinc transporter ZIP13. (351 aa)
RBBP5Retinoblastoma-binding protein 5 isoform B. (539 aa)
PYGO1Uncharacterized protein. (90 aa)
LEO1RNA polymerase-associated protein LEO1. (653 aa)
TLE1Transducin-like enhancer protein 1 isoform A. (828 aa)
TLE4Uncharacterized protein. (980 aa)
TLE1-2Uncharacterized protein. (780 aa)
TCF7Transcription factor 7 isoform A. (452 aa)
HIST1H2BFHistone H2B; Belongs to the histone H2B family. (126 aa)
HIST2H2BEHistone H2B; Belongs to the histone H2B family. (126 aa)
Y1Q_0020100Histone H2B; Belongs to the histone H2B family. (126 aa)
Y1Q_0020098Histone H2B; Belongs to the histone H2B family. (166 aa)
TCF7L1Transcription factor 7-like 1 isoform D. (567 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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