74 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAV2	Uncharacterized protein. (839 aa)
	ARHGEF40L	Rho guanine nucleotide exchange factor 40 isoform A. (1025 aa)
	ARHGEF17	Rho guanine nucleotide exchange factor 17 isoform A. (1659 aa)
	NGF	Beta-nerve growth factor; Belongs to the NGF-beta family. (329 aa)
	ARHGEF11-2	Rho guanine nucleotide exchange factor 11-like. (99 aa)
	CASP3	Caspase-3; Belongs to the peptidase C14A family. (292 aa)
	ARHGEF5	Rho guanine nucleotide exchange factor 5 isoform B. (1796 aa)
	NGFR	Tumor necrosis factor receptor superfamily member 16. (427 aa)
	PSEN1-1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
	TRIO	Uncharacterized protein. (3024 aa)
	ARHGEF39	Rho guanine nucleotide exchange factor 39. (342 aa)
	ARHGEF1L	Rho guanine nucleotide exchange factor 1 isoform A. (930 aa)
	ARHGEF28	Rho guanine nucleotide exchange factor 28 isoform B. (1520 aa)
	ARHGEF1A	Rho guanine nucleotide exchange factor 2 isoform B. (970 aa)
	MCF2L	Uncharacterized protein. (1170 aa)
	Y1Q_0006163	betaPIX_CC domain-containing protein. (231 aa)
	ARHGEF6	Rho guanine nucleotide exchange factor 6 isoform B. (540 aa)
	Y1Q_0013240	Uncharacterized protein. (82 aa)
	SPATA13	Spermatogenesis-associated protein 13. (1708 aa)
	NGEF	Ephexin-1. (569 aa)
	SCARB1	Scavenger receptor class B member 1 isoform A. (959 aa)
	PSENEN	Gamma-secretase subunit PEN-2 isoform A. (81 aa)
	ARHGEF40	Rho guanine nucleotide exchange factor 40. (294 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12 isoform A. (1601 aa)
	NET1-2	Uncharacterized protein. (556 aa)
	ARHGEF9	Uncharacterized protein. (840 aa)
	ARHGEF10	DH domain-containing protein. (1355 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (815 aa)
	ARHGEF11	Rho guanine nucleotide exchange factor 11 isoform C. (1419 aa)
	ITGB3BP	Centromere protein R. (181 aa)
	FGD4	Uncharacterized protein. (831 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (590 aa)
	FGD2	FYVE, RhoGEF and PH domain-containing protein 2. (696 aa)
	MCF2-2	Uncharacterized protein. (1034 aa)
	ARHGEF6-2	Uncharacterized protein. (785 aa)
	AATF	Protein AATF. (571 aa)
	Y1Q_0006107	Rho guanine nucleotide exchange factor 7. (376 aa)
	ARHGEF16	Rho guanine nucleotide exchange factor 16. (628 aa)
	SOS1-1	Son of sevenless-like protein 1 isoform A. (1305 aa)
	GNA13	Guanine nucleotide-binding protein subunit alpha-13. (422 aa)
	FGD3	FYVE, RhoGEF and PH domain-containing protein 3. (917 aa)
	NET1	Neuroepithelial cell-transforming 1 protein isoform A. (591 aa)
	C1GALT1A	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A. (432 aa)
	TGM3-2	Protein-glutamine gamma-glutamyltransferase E-like. (694 aa)
	NRADD	Tumor necrosis factor receptor superfamily member 16. (408 aa)
	TGM3	Protein-glutamine gamma-glutamyltransferase E isoform B. (757 aa)
	Y1Q_0016612	Uncharacterized protein. (94 aa)
	Y1Q_0023273	Uncharacterized protein. (599 aa)
	ARHGEF19	Rho guanine nucleotide exchange factor 19. (851 aa)
	ARHGEF10L	Rho guanine nucleotide exchange factor 10-like protein isoform B. (1322 aa)
	ARHGEF38	Rho guanine nucleotide exchange factor 38 isoform B. (777 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	Y1Q_0020621	DH domain-containing protein. (181 aa)
	ITSN1-2	Uncharacterized protein. (492 aa)
	TIAM1	T-lymphoma invasion and metastasis-inducing protein 1. (1471 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
	APH1A-1	Gamma-secretase subunit APH-1A isoform A. (291 aa)
	AKAP13-1	A-kinase anchor protein 13 isoform B. (1730 aa)
	ARHGEF2	Rho guanine nucleotide exchange factor 2. (994 aa)
	NCSTN	Nicastrin. (718 aa)
	SQSTM1	Sequestosome-1. (457 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37. (697 aa)
	ECT2	Protein ECT2 isoform A. (914 aa)
	MCF2	Proto-oncogene DBL isoform D. (1306 aa)
	ARHGEF25	Rho guanine nucleotide exchange factor 25. (503 aa)
	VAV3-2	Uncharacterized protein. (846 aa)
	ECT2L	Epithelial cell-transforming sequence 2 oncogene-like isoform A. (968 aa)
	TIAM2	Uncharacterized protein. (1768 aa)
	SOS1-2	Son of sevenless-like protein. (1379 aa)
	BCL2L11-1	Bcl-2-like protein 11 isoform C. (178 aa)
	ARHGEF33-1	Rho guanine nucleotide exchange factor 33 isoform A. (769 aa)
	KALRN	Triple functional domain protein. (2926 aa)
	SESTD1	SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
	CASP14-2	Uncharacterized protein; Belongs to the peptidase C14A family. (249 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AATF	RPS27A	A0A151N5W6	A0A151MGG2	Protein AATF.	Ubiquitin-40S ribosomal protein S27a.	0.522
AKAP13-1	ARHGEF16	A0A151M957	A0A151N3Q0	A-kinase anchor protein 13 isoform B.	Rho guanine nucleotide exchange factor 16.	0.412
AKAP13-1	ARHGEF1A	A0A151M957	A0A151NYE4	A-kinase anchor protein 13 isoform B.	Rho guanine nucleotide exchange factor 2 isoform B.	0.907
AKAP13-1	ARHGEF2	A0A151M957	A0A151M954	A-kinase anchor protein 13 isoform B.	Rho guanine nucleotide exchange factor 2.	0.900
AKAP13-1	ARHGEF28	A0A151M957	A0A151NYL6	A-kinase anchor protein 13 isoform B.	Rho guanine nucleotide exchange factor 28 isoform B.	0.652
AKAP13-1	GNA13	A0A151M957	A0A151N2A8	A-kinase anchor protein 13 isoform B.	Guanine nucleotide-binding protein subunit alpha-13.	0.438
AKAP13-1	ITSN1-2	A0A151M957	A0A151ME63	A-kinase anchor protein 13 isoform B.	Uncharacterized protein.	0.532
APH1A-1	NCSTN	A0A151MAM0	A0A151M7G2	Gamma-secretase subunit APH-1A isoform A.	Nicastrin.	0.953
APH1A-1	PSEN1-1	A0A151MAM0	A0A151P354	Gamma-secretase subunit APH-1A isoform A.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.952
APH1A-1	PSENEN	A0A151MAM0	A0A151NRU4	Gamma-secretase subunit APH-1A isoform A.	Gamma-secretase subunit PEN-2 isoform A.	0.952
ARHGEF10	ARHGEF1A	A0A151NLH0	A0A151NYE4	DH domain-containing protein.	Rho guanine nucleotide exchange factor 2 isoform B.	0.485
ARHGEF10	ARHGEF33-1	A0A151NLH0	A0A151M1J3	DH domain-containing protein.	Rho guanine nucleotide exchange factor 33 isoform A.	0.578
ARHGEF10L	ARHGEF19	A0A151MJ66	A0A151MJ77	Rho guanine nucleotide exchange factor 10-like protein isoform B.	Rho guanine nucleotide exchange factor 19.	0.436
ARHGEF11	ARHGEF11-2	A0A151NKM7	A0A151PEC7	Rho guanine nucleotide exchange factor 11 isoform C.	Rho guanine nucleotide exchange factor 11-like.	0.550
ARHGEF11	ARHGEF12	A0A151NKM7	A0A151NQB3	Rho guanine nucleotide exchange factor 11 isoform C.	Rho guanine nucleotide exchange factor 12 isoform A.	0.900
ARHGEF11	ARHGEF17	A0A151NKM7	A0A151PJ54	Rho guanine nucleotide exchange factor 11 isoform C.	Rho guanine nucleotide exchange factor 17 isoform A.	0.410
ARHGEF11	ARHGEF19	A0A151NKM7	A0A151MJ77	Rho guanine nucleotide exchange factor 11 isoform C.	Rho guanine nucleotide exchange factor 19.	0.422
ARHGEF11	ARHGEF33-1	A0A151NKM7	A0A151M1J3	Rho guanine nucleotide exchange factor 11 isoform C.	Rho guanine nucleotide exchange factor 33 isoform A.	0.620
ARHGEF11	ECT2	A0A151NKM7	A0A151M6J6	Rho guanine nucleotide exchange factor 11 isoform C.	Protein ECT2 isoform A.	0.538
ARHGEF11	FGD3	A0A151NKM7	A0A151MZA0	Rho guanine nucleotide exchange factor 11 isoform C.	FYVE, RhoGEF and PH domain-containing protein 3.	0.448