17 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NKX2-2	Homeobox protein Nkx-2.2. (232 aa)
	HNF1A	Hepatocyte nuclear factor 1-alpha. (634 aa)
	NEUROD4	Neurogenic differentiation factor. (332 aa)
	PDX1	Pancreas/duodenum homeobox protein 1. (206 aa)
	AKT2	Non-specific serine/threonine protein kinase. (270 aa)
	AKT3-2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	NEUROD1	Neurogenic differentiation factor. (383 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	Y1Q_0018485	Paired box protein Pax-6-like. (281 aa)
	RFX6	DNA-binding protein RFX6 isoform B. (944 aa)
	NKX6-1	Homeobox protein Nkx-6.1. (336 aa)
	PAX6	Paired box protein Pax-6. (516 aa)
	Y1Q_0017424	Uncharacterized protein. (235 aa)
	NEUROD2	Neurogenic differentiation factor. (355 aa)
	NKX6-2	Homeobox protein Nkx-6.2. (154 aa)
	RFX4	Transcription factor RFX4 isoform A. (745 aa)
	FOXA3	Hepatocyte nuclear factor 3-gamma. (419 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	AKT3	A0A151MPY5	A0A151M239	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	AKT3-2	A0A151MPY5	A0A151MH49	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	Y1Q_0017424	A0A151MPY5	A0A151PCN9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.899
AKT3	AKT2	A0A151M239	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3	AKT3-2	A0A151M239	A0A151MH49	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT3-2	AKT2	A0A151MH49	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3-2	AKT3	A0A151MH49	A0A151M239	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
FOXA3	HNF1A	A0A151NDG2	A0A151N4D0	Hepatocyte nuclear factor 3-gamma.	Hepatocyte nuclear factor 1-alpha.	0.578
FOXA3	NKX2-2	A0A151NDG2	A0A151ND52	Hepatocyte nuclear factor 3-gamma.	Homeobox protein Nkx-2.2.	0.464
HNF1A	FOXA3	A0A151N4D0	A0A151NDG2	Hepatocyte nuclear factor 1-alpha.	Hepatocyte nuclear factor 3-gamma.	0.578
HNF1A	PDX1	A0A151N4D0	A0A151MSA9	Hepatocyte nuclear factor 1-alpha.	Pancreas/duodenum homeobox protein 1.	0.508
NEUROD1	PAX6	A0A151LZT9	A0A151MBV0	Neurogenic differentiation factor.	Paired box protein Pax-6.	0.577
NKX2-2	FOXA3	A0A151ND52	A0A151NDG2	Homeobox protein Nkx-2.2.	Hepatocyte nuclear factor 3-gamma.	0.464
NKX2-2	NKX6-1	A0A151ND52	A0A151M441	Homeobox protein Nkx-2.2.	Homeobox protein Nkx-6.1.	0.452
NKX2-2	NKX6-2	A0A151ND52	A0A151NZE6	Homeobox protein Nkx-2.2.	Homeobox protein Nkx-6.2.	0.440
NKX2-2	PAX6	A0A151ND52	A0A151MBV0	Homeobox protein Nkx-2.2.	Paired box protein Pax-6.	0.496
NKX6-1	NKX2-2	A0A151M441	A0A151ND52	Homeobox protein Nkx-6.1.	Homeobox protein Nkx-2.2.	0.452
NKX6-1	PDX1	A0A151M441	A0A151MSA9	Homeobox protein Nkx-6.1.	Pancreas/duodenum homeobox protein 1.	0.400
NKX6-2	NKX2-2	A0A151NZE6	A0A151ND52	Homeobox protein Nkx-6.2.	Homeobox protein Nkx-2.2.	0.440
PAX6	NEUROD1	A0A151MBV0	A0A151LZT9	Paired box protein Pax-6.	Neurogenic differentiation factor.	0.577