29 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AHRR	Aryl hydrocarbon receptor repressor isoform A. (577 aa)
	FDX1LL	Adrenodoxin. (191 aa)
	PTGIS	Prostacyclin synthase; Belongs to the cytochrome P450 family. (510 aa)
	FDX1-1	Adrenodoxin, mitochondrial isoform B. (207 aa)
	Y1Q_0015961	Uncharacterized protein; Belongs to the cytochrome P450 family. (247 aa)
	FDX1L	Adrenodoxin-like protein, mitochondrial. (172 aa)
	FADS6	Fatty acid desaturase 6. (400 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (489 aa)
	CCDC160	Coiled-coil domain-containing protein 160 isoform A. (303 aa)
	NR1H4	Bile acid receptor. (453 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator isoform A. (785 aa)
	Y1Q_0008984	Cytochrome P450 11B, mitochondrial-like; Belongs to the cytochrome P450 family. (168 aa)
	ARNT2	Uncharacterized protein. (749 aa)
	CYP19A1	Aromatase; Belongs to the cytochrome P450 family. (541 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (458 aa)
	CYP1B1	Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (551 aa)
	CYP7B1	25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
	Y1Q_0021662	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	CYP46A1	Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa)
	CYP4V2	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	CYP11B1	Cytochrome P450 11B1, mitochondrial. (331 aa)
	CYP8B1	Cytochrome P450, family 8, subfamily B; Belongs to the cytochrome P450 family. (497 aa)
	Y1Q_0008691	Uncharacterized protein. (686 aa)
	AHR2	Aryl hydrocarbon receptor 2. (1104 aa)
	CYP39A1	24-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (468 aa)
	POMC	Pro-opiomelanocortin. (287 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (278 aa)
	CYP51A1	Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (500 aa)
	AHR	Aryl hydrocarbon receptor. (522 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ARNT	A0A151MQE2	A0A151M5M1	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator isoform A.	0.823
AHR	ARNT2	A0A151MQE2	A0A151M9B3	Aryl hydrocarbon receptor.	Uncharacterized protein.	0.823
AHR2	ARNT	A0A151NAH3	A0A151M5M1	Aryl hydrocarbon receptor 2.	Aryl hydrocarbon receptor nuclear translocator isoform A.	0.846
AHR2	ARNT2	A0A151NAH3	A0A151M9B3	Aryl hydrocarbon receptor 2.	Uncharacterized protein.	0.868
AHR2	CYP1B1	A0A151NAH3	A0A151MHA0	Aryl hydrocarbon receptor 2.	Cytochrome P450 1B1; Belongs to the cytochrome P450 family.	0.481
AHRR	ARNT	A0A151NCT0	A0A151M5M1	Aryl hydrocarbon receptor repressor isoform A.	Aryl hydrocarbon receptor nuclear translocator isoform A.	0.778
AHRR	ARNT2	A0A151NCT0	A0A151M9B3	Aryl hydrocarbon receptor repressor isoform A.	Uncharacterized protein.	0.778
AHRR	CYP1B1	A0A151NCT0	A0A151MHA0	Aryl hydrocarbon receptor repressor isoform A.	Cytochrome P450 1B1; Belongs to the cytochrome P450 family.	0.425
ARNT	AHR	A0A151M5M1	A0A151MQE2	Aryl hydrocarbon receptor nuclear translocator isoform A.	Aryl hydrocarbon receptor.	0.823
ARNT	AHR2	A0A151M5M1	A0A151NAH3	Aryl hydrocarbon receptor nuclear translocator isoform A.	Aryl hydrocarbon receptor 2.	0.846
ARNT	AHRR	A0A151M5M1	A0A151NCT0	Aryl hydrocarbon receptor nuclear translocator isoform A.	Aryl hydrocarbon receptor repressor isoform A.	0.778
ARNT	Y1Q_0008691	A0A151M5M1	A0A151N9J1	Aryl hydrocarbon receptor nuclear translocator isoform A.	Uncharacterized protein.	0.823
ARNT2	AHR	A0A151M9B3	A0A151MQE2	Uncharacterized protein.	Aryl hydrocarbon receptor.	0.823
ARNT2	AHR2	A0A151M9B3	A0A151NAH3	Uncharacterized protein.	Aryl hydrocarbon receptor 2.	0.868
ARNT2	AHRR	A0A151M9B3	A0A151NCT0	Uncharacterized protein.	Aryl hydrocarbon receptor repressor isoform A.	0.778
ARNT2	Y1Q_0008691	A0A151M9B3	A0A151N9J1	Uncharacterized protein.	Uncharacterized protein.	0.823
CYP11A1	CYP7A1	A0A151MAJ0	A0A151MNT9	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.509
CYP11A1	CYP7B1	A0A151MAJ0	A0A151MNN1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family.	0.948
CYP11A1	FADS6	A0A151MAJ0	A0A151N2X5	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Fatty acid desaturase 6.	0.512
CYP11A1	FDX1-1	A0A151MAJ0	A0A151P753	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Adrenodoxin, mitochondrial isoform B.	0.601