STRINGSTRING
TET3 TET3 Y1Q_0020098 Y1Q_0020098 Y1Q_0020100 Y1Q_0020100 HIST2H2BE HIST2H2BE HIST1H2BF HIST1H2BF BAZ2B BAZ2B TBPL2 TBPL2 TBP TBP MTF2 MTF2 POLR2H POLR2H ZNRD1 ZNRD1 SMARCA5-2 SMARCA5-2 POLR1B POLR1B GSK3B-2 GSK3B-2 Y1Q_0003135 Y1Q_0003135 PHF19 PHF19 POLR1C POLR1C Y1Q_0012287 Y1Q_0012287 DNMT3B-2 DNMT3B-2 TET2 TET2 ERCC6 ERCC6 MYO1C MYO1C Y1Q_0021955 Y1Q_0021955 RBBP4-2 RBBP4-2 DEK DEK JARID2 JARID2 Y1Q_0012291 Y1Q_0012291 TWISTNB TWISTNB KAT2B KAT2B Y1Q_0016948 Y1Q_0016948 CD3EAP CD3EAP MYO1A MYO1A TAF1C TAF1C RBBP4 RBBP4 BAZ2A BAZ2A GSK3B GSK3B SUZ12 SUZ12 SAP30BP SAP30BP MYBBP1A MYBBP1A TAF1B TAF1B RRP8 RRP8 Y1Q_0009388 Y1Q_0009388 BAZ1B BAZ1B SF3B1 SF3B1 MYO1B-2 MYO1B-2 POLR1E POLR1E CREBBP CREBBP POLR2F POLR2F Y1Q_0024039 Y1Q_0024039 TDG TDG AEBP2-1 AEBP2-1 Y1Q_0016099 Y1Q_0016099 POLR2L-2 POLR2L-2 EED EED H2AFZ H2AFZ SMARCA5 SMARCA5 HIST1H2B5L HIST1H2B5L H2AFV H2AFV DNMT3B DNMT3B DNMT3L DNMT3L HIST1H4D HIST1H4D Y1Q_0006757 Y1Q_0006757 SAP130 SAP130 PHF1 PHF1 POLR2L-1 POLR2L-1 TET1 TET1 DDX50 DDX50 DDX50-2 DDX50-2 POLR2E POLR2E EZH2 EZH2 TAF1D TAF1D TAF1A-1 TAF1A-1 MYO1G MYO1G Y1Q_0014681 Y1Q_0014681 POLR1A POLR1A EZH1 EZH1 MYO1D MYO1D Y1Q_0018383 Y1Q_0018383 DHX58 DHX58 Y1Q_0014479 Y1Q_0014479 Y1Q_0012805 Y1Q_0012805 DNMT1 DNMT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TET3CXXC-type domain-containing protein. (2028 aa)
Y1Q_0020098Histone H2B; Belongs to the histone H2B family. (166 aa)
Y1Q_0020100Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST2H2BEHistone H2B; Belongs to the histone H2B family. (126 aa)
HIST1H2BFHistone H2B; Belongs to the histone H2B family. (126 aa)
BAZ2BBromodomain adjacent to zinc finger domain protein 2B. (2762 aa)
TBPL2TATA box-binding protein-like protein 2. (331 aa)
TBPTATA-box-binding protein. (301 aa)
MTF2Metal-response element-binding transcription factor 2. (595 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (161 aa)
ZNRD1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
SMARCA5-2Uncharacterized protein. (1027 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1078 aa)
GSK3B-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
Y1Q_0003135Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (127 aa)
PHF19PHD finger protein 19 isoform B. (588 aa)
POLR1CDNA-directed RNA polymerases I and III subunit RPAC1. (346 aa)
Y1Q_0012287Unconventional myosin-Ig-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (293 aa)
DNMT3B-2Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (858 aa)
TET2Methylcytosine dioxygenase TET2. (734 aa)
ERCC6DNA excision repair protein ERCC-6. (1491 aa)
MYO1CUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (977 aa)
Y1Q_0021955Unconventional myosin-Ic-like. (117 aa)
RBBP4-2WD_REPEATS_REGION domain-containing protein. (425 aa)
DEKProtein DEK. (367 aa)
JARID2Protein Jumonji. (1183 aa)
Y1Q_0012291TH1 domain-containing protein. (164 aa)
TWISTNBDNA-directed RNA polymerase I subunit RPA43. (317 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (783 aa)
Y1Q_0016948Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1238 aa)
CD3EAPDNA-directed RNA polymerase I subunit RPA34. (226 aa)
MYO1AUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (576 aa)
TAF1CTATA box-binding protein-associated factor RNA polymerase I subunit C. (117 aa)
RBBP4Histone-binding protein RBBP4. (424 aa)
BAZ2ABromodomain adjacent to zinc finger domain protein 2A. (1718 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (413 aa)
SUZ12Polycomb protein SUZ12. (667 aa)
SAP30BPSAP30-binding protein. (311 aa)
MYBBP1AMyb-binding protein 1A. (1143 aa)
TAF1BTATA box-binding protein-associated factor RNA polymerase I subunit B. (592 aa)
RRP8Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (108 aa)
Y1Q_0009388Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
BAZ1BTyrosine-protein kinase BAZ1B. (1489 aa)
SF3B1Splicing factor 3B subunit 1. (1301 aa)
MYO1B-2Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1181 aa)
POLR1EDNA-directed RNA polymerase I subunit RPA49. (417 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
TDGG/T mismatch-specific thymine DNA glycosylase. (404 aa)
AEBP2-1Zinc finger protein AEBP2 isoform B. (455 aa)
Y1Q_0016099Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2L-2DNA-directed RNA polymerases I, II, and III subunit RPABC5. (74 aa)
EEDPolycomb protein EED. (427 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1053 aa)
HIST1H2B5LHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AFVHistone H2A; Belongs to the histone H2A family. (128 aa)
DNMT3BDNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (727 aa)
DNMT3LDNA (Cytosine-5)-methyltransferase 3-like. (387 aa)
HIST1H4DHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Y1Q_0006757Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa)
SAP130Histone deacetylase complex subunit SAP130 isoform A. (1059 aa)
PHF1PHD finger protein 1 isoform B. (569 aa)
POLR2L-1DNA-directed RNA polymerases I, II, and III subunit RPABC5. (104 aa)
TET1Methylcytosine dioxygenase TET1 isoform A. (691 aa)
DDX50Nucleolar RNA helicase 2. (692 aa)
DDX50-2Uncharacterized protein. (684 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (231 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform A. (806 aa)
TAF1DTATA box-binding protein-associated factor RNA polymerase I subunit D. (330 aa)
TAF1A-1TATA box-binding protein-associated factor RNA polymerase I subunit A isoform B. (454 aa)
MYO1GMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (514 aa)
Y1Q_0014681Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (119 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1689 aa)
EZH1Uncharacterized protein. (751 aa)
MYO1DUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
Y1Q_0018383Histone H2B-like; Belongs to the histone H2B family. (152 aa)
DHX58Putative ATP-dependent RNA helicase DHX58 isoform E; Belongs to the small heat shock protein (HSP20) family. (1743 aa)
Y1Q_0014479Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
Y1Q_0012805Histone H2B; Belongs to the histone H2B family. (118 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1505 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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