86 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Y1Q_0016093	Uncharacterized protein. (165 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (757 aa)
	DPP4-2	Uncharacterized protein; Belongs to the peptidase S9B family. (992 aa)
	DPP10	Inactive dipeptidyl peptidase 10 isoform A; Belongs to the peptidase S9B family. (801 aa)
	INHBB	Uncharacterized protein. (132 aa)
	EXOC5	Exocyst complex component 5. (708 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (474 aa)
	EXOC8	Exocyst complex component 8. (727 aa)
	ERO1B-2	Uncharacterized protein. (471 aa)
	SLC30A7	Zinc transporter 7. (348 aa)
	Y1Q_0006822	COesterase domain-containing protein. (200 aa)
	Y1Q_0006823	COesterase domain-containing protein. (211 aa)
	EXOC3L2	Exocyst complex component 3-like protein 2 isoform B. (761 aa)
	Y1Q_0006815	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (563 aa)
	CDX1-1	Homeobox protein CDX-1 isoform A. (258 aa)
	CUNH9orf3	Aminopeptidase O. (836 aa)
	DPP9	Dipeptidyl peptidase 9 isoform B; Belongs to the peptidase S9B family. (928 aa)
	SLC30A4	Zinc transporter 4. (307 aa)
	ISL2	Insulin enhancer protein ISL-2. (346 aa)
	SEC11A	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	PAX6	Paired box protein Pax-6. (516 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (147 aa)
	GNB3	WD_REPEATS_REGION domain-containing protein. (340 aa)
	PCSK2	Neuroendocrine convertase 2; Belongs to the peptidase S8 family. (637 aa)
	SLC30A6	Zinc transporter 6. (461 aa)
	ENPEP	Aminopeptidase. (970 aa)
	GHRL-1	Appetite-regulating hormone isoform B. (145 aa)
	CPA6	Carboxypeptidase A6. (438 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (168 aa)
	Y1Q_0005149	Free fatty acid receptor 1-like. (285 aa)
	SEC11C	Signal peptidase complex catalytic subunit SEC11. (177 aa)
	GRP	Gastrin-releasing peptide. (98 aa)
	SLC30A8	Zinc transporter 8. (384 aa)
	EXOC3L1	Exocyst complex component 3-like protein. (744 aa)
	EXOC6B-2	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (825 aa)
	P4HB	Protein disulfide-isomerase. (512 aa)
	INHA	Inhibin alpha chain. (283 aa)
	PHEX	Phosphate-regulating neutral endopeptidase. (751 aa)
	ACE2	Angiotensin-converting enzyme. (805 aa)
	TMEM27	Collectrin. (251 aa)
	Y1Q_0018485	Paired box protein Pax-6-like. (281 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	EXOC7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (705 aa)
	TTC34-1	Tetratricopeptide repeat protein 34 isoform C. (1711 aa)
	CPO	Carboxypeptidase O. (295 aa)
	ALX3-1	Homeobox protein aristaless-like 3 isoform B. (203 aa)
	CPB1	Carboxypeptidase B preproprotein. (414 aa)
	MME	Neprilysin. (794 aa)
	GPR119	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (346 aa)
	BCHE	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (619 aa)
	CPA3	Mast cell carboxypeptidase A preproprotein. (418 aa)
	EXOC3	Exocyst complex component 3. (753 aa)
	INHBE	Inhibin beta E chain. (352 aa)
	EXOC2	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (922 aa)
	SPCS1	Signal peptidase complex subunit 1. (100 aa)
	IGF1	Insulin-like growth factor I. (153 aa)
	CDX4L	Homeobox protein CDX-4. (277 aa)
	CDX4	Homeobox protein CDX-4. (248 aa)
	EXOC4-2	Uncharacterized protein. (587 aa)
	EXOC4	Exocyst complex component 4. (357 aa)
	ATP6AP2	Renin receptor. (352 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	EXOC6B	Exocyst complex component 6B. (1322 aa)
	FFAR4	Free fatty acid receptor 4. (353 aa)
	POMC	Pro-opiomelanocortin. (287 aa)
	DPP9-2	Uncharacterized protein; Belongs to the peptidase S9B family. (860 aa)
	Y1Q_0017506	TGF_BETA_2 domain-containing protein. (424 aa)
	GIP	Gastric inhibitory polypeptide. (185 aa)
	PDIA2	Protein disulfide-isomerase. (539 aa)
	Y1Q_0007359	Sec3-PIP2_bind domain-containing protein. (667 aa)
	Y1Q_0015062	Uncharacterized protein. (497 aa)
	EXOC3L4	Exocyst complex component 3-like protein 4. (748 aa)
	TNFAIP2	Tumor necrosis factor alpha-induced protein 2. (659 aa)
	CEP135	Centrosomal protein of isoform B. (2028 aa)
	SPCS3	Signal peptidase complex subunit 3. (180 aa)
	CPE	Carboxypeptidase E. (403 aa)
	ACE	Angiotensin-converting enzyme. (1244 aa)
	GH	Somatotropin. (231 aa)
	DPP6	Uncharacterized protein; Belongs to the peptidase S9B family. (801 aa)
	ACHE	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (891 aa)
	LHB	Luteinizing hormone, beta polypeptide. (87 aa)
	TSHB	Thyrotropin subunit beta. (146 aa)
	PCSK1-2	Uncharacterized protein; Belongs to the peptidase S8 family. (422 aa)
	SLC30A5	Zinc transporter 5. (771 aa)
	Y1Q_0013974	Sialic acid-binding Ig-like lectin 5. (329 aa)
	SPCS2	Signal peptidase complex subunit 2. (201 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE	ACE2	A0A151PC80	A0A151N089	Angiotensin-converting enzyme.	Angiotensin-converting enzyme.	0.433
ACE	ACHE	A0A151PC80	A0A151PFY5	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family.	0.456
ACE	AGT	A0A151PC80	A0A151M2N2	Angiotensin-converting enzyme.	Angiotensinogen; Belongs to the serpin family.	0.968
ACE	CDX4	A0A151PC80	A0A151NNB3	Angiotensin-converting enzyme.	Homeobox protein CDX-4.	0.400
ACE	CDX4L	A0A151PC80	A0A151NNA4	Angiotensin-converting enzyme.	Homeobox protein CDX-4.	0.400
ACE	DPP4-2	A0A151PC80	A0A151M0D2	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.540
ACE	INS	A0A151PC80	A0A151MCB0	Angiotensin-converting enzyme.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.504
ACE	TMEM27	A0A151PC80	A0A151N0G6	Angiotensin-converting enzyme.	Collectrin.	0.514
ACE2	ACE	A0A151N089	A0A151PC80	Angiotensin-converting enzyme.	Angiotensin-converting enzyme.	0.433
ACE2	AGT	A0A151N089	A0A151M2N2	Angiotensin-converting enzyme.	Angiotensinogen; Belongs to the serpin family.	0.924
ACE2	DPP4	A0A151N089	A0A151M0A4	Angiotensin-converting enzyme.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.708
ACE2	DPP4-2	A0A151N089	A0A151M0D2	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.790
ACE2	INS	A0A151N089	A0A151MCB0	Angiotensin-converting enzyme.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.404
ACHE	ACE	A0A151PFY5	A0A151PC80	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family.	Angiotensin-converting enzyme.	0.456
ACHE	GHRL-1	A0A151PFY5	A0A151MK48	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family.	Appetite-regulating hormone isoform B.	0.623
ACHE	Y1Q_0006815	A0A151PFY5	A0A151M601	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.905
AGT	ACE	A0A151M2N2	A0A151PC80	Angiotensinogen; Belongs to the serpin family.	Angiotensin-converting enzyme.	0.968
AGT	ACE2	A0A151M2N2	A0A151N089	Angiotensinogen; Belongs to the serpin family.	Angiotensin-converting enzyme.	0.924
AGT	ATP6AP2	A0A151M2N2	A0A151NQQ9	Angiotensinogen; Belongs to the serpin family.	Renin receptor.	0.844
AGT	CPA6	A0A151M2N2	A0A151MNA9	Angiotensinogen; Belongs to the serpin family.	Carboxypeptidase A6.	0.449