27 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (114 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (873 aa)
	Y1Q_0011506	Rap guanine nucleotide exchange factor 4-like. (169 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (757 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
	RAPGEF3	Uncharacterized protein. (874 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	Y1Q_0011868	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (1680 aa)
	Y1Q_0023796	Uncharacterized protein. (1088 aa)
	ITPR2-2	Uncharacterized protein. (2702 aa)
	RAPGEF5A	Rap guanine nucleotide exchange factor 5 isoform A. (865 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (228 aa)
	THAP1	THAP domain-containing protein 1. (169 aa)
	KCNG2-2	BTB domain-containing protein; Belongs to the potassium channel family. (517 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily. (368 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	Y1Q_0006499	Uncharacterized protein; Belongs to the protein kinase superfamily. (401 aa)
	THAP7-1	THAP domain-containing protein 8 isoform A. (758 aa)
	Y1Q_0002754	Potassium voltage-gated channel subfamily B member 1-like. (206 aa)
	KCNB2	Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (674 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (155 aa)
	GLP1R	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (438 aa)
	ITPR3	Uncharacterized protein. (2667 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor-like 1. (562 aa)
	KCNS3A	Potassium voltage-gated channel subfamily S member 3; Belongs to the potassium channel family. (555 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DPP4	GLP1R	A0A151M0A4	A0A151P334	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.956
DPP4	GNB4	A0A151M0A4	A0A151M6J3	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit beta-4.	0.687
DPP4	GNG12	A0A151M0A4	A0A151NJB1	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.545
DPP4	GNG13	A0A151M0A4	A0A151N235	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.609
DPP4	GNG2	A0A151M0A4	A0A151N3B0	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.590
DPP4	GNG3	A0A151M0A4	A0A151LZJ9	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.475
DPP4	GNG4	A0A151M0A4	A0A151M2U9	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.590
DPP4	GNG8	A0A151M0A4	A0A151P1V9	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.475
DPP4	Y1Q_0011868	A0A151M0A4	A0A151MHW5	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.474
GLP1R	DPP4	A0A151P334	A0A151M0A4	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.956
GLP1R	GNB4	A0A151P334	A0A151M6J3	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-4.	0.906
GLP1R	GNG12	A0A151P334	A0A151NJB1	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.601
GLP1R	GNG13	A0A151P334	A0A151N235	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.657
GLP1R	GNG2	A0A151P334	A0A151N3B0	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.634
GLP1R	GNG3	A0A151P334	A0A151LZJ9	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
GLP1R	GNG4	A0A151P334	A0A151M2U9	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.634
GLP1R	GNG8	A0A151P334	A0A151P1V9	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
GLP1R	Y1Q_0011868	A0A151P334	A0A151MHW5	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.539
GNB4	DPP4	A0A151M6J3	A0A151M0A4	Guanine nucleotide-binding protein subunit beta-4.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.687
GNB4	GLP1R	A0A151M6J3	A0A151P334	Guanine nucleotide-binding protein subunit beta-4.	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.906