34 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKT3-2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	Y1Q_0003612	Rho-GAP domain-containing protein. (189 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (281 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (938 aa)
	Y1Q_0014440	Protein kinase domain-containing protein. (175 aa)
	Y1Q_0017424	Uncharacterized protein. (235 aa)
	SRC-2	Tyrosine-protein kinase. (546 aa)
	Y1Q_0023424	Ig-like domain-containing protein. (156 aa)
	PAK3	Non-specific serine/threonine protein kinase. (526 aa)
	Y1Q_0015649	Uncharacterized protein. (1191 aa)
	GRAP2	GRB2-related adapter protein 2. (382 aa)
	Y1Q_0003573	SH3 domain-containing protein. (167 aa)
	YES1	Tyrosine-protein kinase. (1013 aa)
	CD28	T-cell-specific surface glycoprotein CD28. (226 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha. (727 aa)
	PRR5	Proline-rich protein 5 isoform B. (468 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	CDC42	Cell division control 42-like protein. (235 aa)
	PIK3R1-2	Uncharacterized protein. (750 aa)
	RICTOR	Rapamycin-insensitive companion of mTOR. (1439 aa)
	C1GALT1A	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A. (432 aa)
	AKT2	Non-specific serine/threonine protein kinase. (270 aa)
	Y1Q_0018542	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (627 aa)
	LYN	Tyrosine-protein kinase. (562 aa)
	CD276	CD276 antigen isoform A. (338 aa)
	PAK2-2	Non-specific serine/threonine protein kinase. (741 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1. (515 aa)
	FNDC3A-2	Uncharacterized protein. (1195 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1011 aa)
	Y1Q_0010680	Uncharacterized protein. (176 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PAK2	Non-specific serine/threonine protein kinase. (546 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	CD86	T-lymphocyte activation antigen CD86. (344 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	AKT3	A0A151MPY5	A0A151M239	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	AKT3-2	A0A151MPY5	A0A151MH49	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	CDC42	A0A151MPY5	A0A151MZN3	Non-specific serine/threonine protein kinase.	Cell division control 42-like protein.	0.449
AKT2	LYN	A0A151MPY5	A0A151MNT0	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.411
AKT2	MAP3K8	A0A151MPY5	A0A151PD37	Non-specific serine/threonine protein kinase.	Mitogen-activated protein kinase kinase kinase 8.	0.460
AKT2	PDPK1	A0A151MPY5	A0A151MHZ4	Non-specific serine/threonine protein kinase.	3-phosphoinositide-dependent protein kinase 1.	0.851
AKT2	PIK3CB	A0A151MPY5	A0A151M6C3	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.948
AKT2	PIK3R1	A0A151MPY5	A0A151N8Y8	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.943
AKT2	PIK3R1-2	A0A151MPY5	A0A151MXN9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.943
AKT2	RICTOR	A0A151MPY5	A0A151MWZ3	Non-specific serine/threonine protein kinase.	Rapamycin-insensitive companion of mTOR.	0.784
AKT2	SRC-2	A0A151MPY5	A0A151NZW6	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.540
AKT2	Y1Q_0003573	A0A151MPY5	A0A151NGA7	Non-specific serine/threonine protein kinase.	SH3 domain-containing protein.	0.461
AKT2	Y1Q_0003612	A0A151MPY5	A0A151PFY9	Non-specific serine/threonine protein kinase.	Rho-GAP domain-containing protein.	0.461
AKT2	Y1Q_0014440	A0A151MPY5	A0A151PCS5	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.460
AKT2	Y1Q_0017424	A0A151MPY5	A0A151PCN9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.899
AKT2	Y1Q_0018542	A0A151MPY5	A0A151MP29	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.509
AKT2	YES1	A0A151MPY5	A0A151NF04	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.524
AKT3	AKT2	A0A151M239	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3	AKT3-2	A0A151M239	A0A151MH49	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT3	CDC42	A0A151M239	A0A151MZN3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division control 42-like protein.	0.449