STRINGSTRING
Y1Q_0017691 Y1Q_0017691 PTH2R PTH2R GNG3 GNG3 PDE11A PDE11A Y1Q_0011461 Y1Q_0011461 DPP4 DPP4 SCTR SCTR GPR39 GPR39 GPHB5 GPHB5 PDE10A PDE10A GNG4 GNG4 PDE7B PDE7B TSHR TSHR GNB4 GNB4 HTR4 HTR4 ADRB2 ADRB2 DRD1 DRD1 PDE8B PDE8B PTH PTH ADM ADM CALCA CALCA PDE3B PDE3B GNB3 GNB3 GPR15 GPR15 GPR21 GPR21 Y1Q_0011868 Y1Q_0011868 HTR6 HTR6 Y1Q_0023772 Y1Q_0023772 GPR27 GPR27 PRKAR2A PRKAR2A RLN3 RLN3 PDE2A PDE2A PDE7A PDE7A RXFP1 RXFP1 GLP2R GLP2R CALCRL CALCRL Y1Q_0015372 Y1Q_0015372 ITGA5 ITGA5 GRK2 GRK2 GPR176 GPR176 Y1Q_0005328 Y1Q_0005328 PTGER4 PTGER4 PDE4D PDE4D AVP AVP HTR7 HTR7 ARRB2 ARRB2 PRKAR1B PRKAR1B GNG13 GNG13 Y1Q_0020680 Y1Q_0020680 FAM83G FAM83G PRKAR1A PRKAR1A GNG2 GNG2 ADORA2A ADORA2A ADM2 ADM2 GIPR GIPR GPR25 GPR25 PTH2R-2 PTH2R-2 CNBD2-1 CNBD2-1 RAMP1-1 RAMP1-1 CALCRL-2 CALCRL-2 ADORA2B ADORA2B Y1Q_0018553 Y1Q_0018553 ADRB3 ADRB3 THAP1 THAP1 ADCYAP1 ADCYAP1 MC4R MC4R Y1Q_0024357 Y1Q_0024357 IAPP IAPP PDE3A PDE3A Y1Q_0017445 Y1Q_0017445 PRKACB PRKACB GNG12 GNG12 Y1Q_0016072 Y1Q_0016072 PDE4B-2 PDE4B-2 Y1Q_0006499 Y1Q_0006499 PTH2 PTH2 PDE4B PDE4B ARR3 ARR3 THAP7-1 THAP7-1 GPR83L GPR83L Y1Q_0015620 Y1Q_0015620 ARR3-2 ARR3-2 PRKAR2B PRKAR2B Y1Q_0015612 Y1Q_0015612 ADRBK1 ADRBK1 ADRB1 ADRB1 GCGR GCGR Y1Q_0016271 Y1Q_0016271 MC3R MC3R GHRH-1 GHRH-1 Y1Q_0002850 Y1Q_0002850 PTGIR PTGIR Y1Q_0022179 Y1Q_0022179 HTR7-2 HTR7-2 GPR84 GPR84 POMC POMC GNG8 GNG8 GPR83 GPR83 HRH2 HRH2 RAMP3 RAMP3 GLP1R GLP1R NPSR1 NPSR1 NPS NPS MC1R MC1R GIP GIP DRD5 DRD5 PTHLH PTHLH GPR20 GPR20 Y1Q_0007451 Y1Q_0007451 DRD5-2 DRD5-2 Y1Q_0021608 Y1Q_0021608 Y1Q_0021609 Y1Q_0021609 RAMP2 RAMP2 RXFP1-2 RXFP1-2 Y1Q_0018338 Y1Q_0018338 GHRHR2 GHRHR2 CRHR1-2 CRHR1-2 VIPR2-1 VIPR2-1 Y1Q_0014569 Y1Q_0014569 GHRHR GHRHR CRHR1 CRHR1 ADCYAP1R1 ADCYAP1R1 GHRH-LR GHRH-LR VIPR1 VIPR1 PTGER2 PTGER2 Y1Q_0014568 Y1Q_0014568 Y1Q_0019944 Y1Q_0019944 TSHB TSHB Y1Q_0003978 Y1Q_0003978
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Y1Q_0017691G_PROTEIN_RECEP_F1_2 domain-containing protein. (350 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (538 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (114 aa)
PDE11APhosphodiesterase. (591 aa)
Y1Q_0011461GAF domain-containing protein. (210 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (757 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (460 aa)
GPR39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (463 aa)
GPHB5Glycoprotein hormone beta-5. (130 aa)
PDE10APhosphodiesterase. (814 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
PDE7BPhosphodiesterase. (443 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (750 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
HTR45-hydroxytryptamine receptor 4 isoform A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
ADRB2Beta-2 adrenergic receptor. (392 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (451 aa)
PDE8BPhosphodiesterase. (768 aa)
PTHParathyroid hormone. (126 aa)
ADMADM. (283 aa)
CALCACalcitonin. (148 aa)
PDE3BPhosphodiesterase. (815 aa)
GNB3WD_REPEATS_REGION domain-containing protein. (340 aa)
GPR15G-protein coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (374 aa)
GPR21Putative G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
Y1Q_0011868Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (436 aa)
Y1Q_0023772Uncharacterized protein. (599 aa)
GPR27Putative G-protein coupled receptor 27. (389 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit. (355 aa)
RLN3Relaxin-3. (130 aa)
PDE2APhosphodiesterase. (925 aa)
PDE7APhosphodiesterase. (484 aa)
RXFP1Relaxin receptor 1 isoform A. (720 aa)
GLP2RGlucagon-like peptide 2 receptor isoform B; Belongs to the G-protein coupled receptor 2 family. (546 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (492 aa)
Y1Q_0015372PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (399 aa)
ITGA5Integrin alpha-5. (671 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
GPR176Putative G-protein coupled receptor 176 isoform B. (541 aa)
Y1Q_0005328Cyclic nucleotide-binding domain-containing protein. (578 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (488 aa)
PDE4DPhosphodiesterase. (678 aa)
AVPVasotocin-neurophysin VT; Belongs to the vasopressin/oxytocin family. (161 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (426 aa)
ARRB2Arrestin_C domain-containing protein. (407 aa)
PRKAR1BUncharacterized protein. (413 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
Y1Q_0020680cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like. (173 aa)
FAM83GProtein FAM83G. (760 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (228 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (436 aa)
ADM2ADM2 preproprotein. (121 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
GPR25Putative G-protein coupled receptor 25; Belongs to the G-protein coupled receptor 1 family. (357 aa)
PTH2R-2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (555 aa)
CNBD2-1Cyclic nucleotide-binding domain-containing protein 2 isoform B. (591 aa)
RAMP1-1Receptor activity-modifying protein 1 isoform A. (144 aa)
CALCRL-2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (451 aa)
ADORA2BAdenosine receptor A2b. (107 aa)
Y1Q_0018553Integrin alpha-5-like. (167 aa)
ADRB3Beta-3 adrenergic receptor. (439 aa)
THAP1THAP domain-containing protein 1. (169 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (184 aa)
MC4RMelanocortin receptor 4. (331 aa)
Y1Q_0024357Uncharacterized protein. (110 aa)
IAPPIslet amyloid polypeptide. (133 aa)
PDE3APhosphodiesterase. (799 aa)
Y1Q_0017445IlGF domain-containing protein. (120 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily. (368 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
Y1Q_0016072Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (437 aa)
PDE4B-2Phosphodiesterase. (644 aa)
Y1Q_0006499Uncharacterized protein; Belongs to the protein kinase superfamily. (401 aa)
PTH2Tuberoinfundibular peptide of 39 residues. (125 aa)
PDE4BPhosphodiesterase. (646 aa)
ARR3Arrestin-C isoform B. (428 aa)
THAP7-1THAP domain-containing protein 8 isoform A. (758 aa)
GPR83LPutative G-protein coupled receptor 83 isoform A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Y1Q_0015620G_PROTEIN_RECEP_F1_2 domain-containing protein. (722 aa)
ARR3-2Arrestin_C domain-containing protein. (394 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit isoform B. (408 aa)
Y1Q_0015612G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (385 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (695 aa)
ADRB1Beta-1 adrenergic receptor. (383 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (499 aa)
Y1Q_0016271cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like. (144 aa)
MC3RMelanocortin receptor 3. (326 aa)
GHRH-1Somatoliberin isoform A. (168 aa)
Y1Q_0002850Beta-1 adrenergic receptor-like; Belongs to the G-protein coupled receptor 1 family. (358 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (324 aa)
Y1Q_0022179D(1)-like dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (322 aa)
HTR7-2G_PROTEIN_RECEP_F1_2 domain-containing protein. (167 aa)
GPR84G-protein coupled receptor 84. (395 aa)
POMCPro-opiomelanocortin. (287 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (155 aa)
GPR83Putative G-protein coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (423 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (399 aa)
RAMP3Receptor activity-modifying protein 3. (159 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (438 aa)
NPSR1Neuropeptide S receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (372 aa)
NPSNeuropeptide S. (162 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (318 aa)
GIPGastric inhibitory polypeptide. (185 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (453 aa)
PTHLHParathyroid hormone-related protein isoform A. (229 aa)
GPR20G-protein coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (428 aa)
Y1Q_0007451Uncharacterized protein. (143 aa)
DRD5-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (388 aa)
Y1Q_0021608Cyclic nucleotide-binding domain-containing protein. (327 aa)
Y1Q_0021609Uncharacterized protein. (110 aa)
RAMP2Receptor activity-modifying protein 2. (169 aa)
RXFP1-2G_PROTEIN_RECEP_F1_2 domain-containing protein. (619 aa)
Y1Q_0018338Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (546 aa)
GHRHR2Growth hormone releasing hormone receptor 2 isoform B; Belongs to the G-protein coupled receptor 2 family. (457 aa)
CRHR1-2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (436 aa)
VIPR2-1Vasoactive intestinal polypeptide receptor 2 isoform B; Belongs to the G-protein coupled receptor 2 family. (441 aa)
Y1Q_0014569G_PROTEIN_RECEP_F2_3 domain-containing protein. (78 aa)
GHRHRGrowth hormone-releasing hormone receptor isoform A; Belongs to the G-protein coupled receptor 2 family. (424 aa)
CRHR1Corticotropin-releasing factor receptor 1 isoform B; Belongs to the G-protein coupled receptor 2 family. (413 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform B. (314 aa)
GHRH-LRVasoactive intestinal polypeptide receptor 1 isoform B; Belongs to the G-protein coupled receptor 2 family. (479 aa)
VIPR1Vasoactive intestinal polypeptide receptor 1 isoform B; Belongs to the G-protein coupled receptor 2 family. (446 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype. (285 aa)
Y1Q_0014568G_PROTEIN_RECEP_F2_3 domain-containing protein. (144 aa)
Y1Q_0019944Prostaglandin D2 receptor-like. (97 aa)
TSHBThyrotropin subunit beta. (146 aa)
Y1Q_0003978Phosphodiesterase. (876 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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