111 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMB5	Proteasome subunit beta type-5. (211 aa)
	IL18BP	Interleukin-18-binding protein. (158 aa)
	PSMD8	26S proteasome non-ATPase regulatory subunit 8. (257 aa)
	NFKBIB	NF-kappa-B inhibitor beta. (109 aa)
	IKBKB	Inhibitor of nuclear factor kappa-B kinase subunit beta. (730 aa)
	KHNYN	Protein KHNYN. (890 aa)
	NFKB2	Uncharacterized protein. (937 aa)
	IRAK4	Interleukin-1 receptor-associated kinase 4. (468 aa)
	LRRC71	Leucine-rich repeat-containing protein 71 isoform B. (526 aa)
	ACAA1	3-ketoacyl-CoA thiolase, peroxisomal isoform B. (1024 aa)
	Y1Q_0022090	Ig-like domain-containing protein. (187 aa)
	MYD88	Myeloid differentiation primary response protein MyD88. (203 aa)
	NKIRAS2	NF-kappa-B inhibitor-interacting Ras-like protein 2. (191 aa)
	MAP3K3-2	Uncharacterized protein. (657 aa)
	STAT4	Signal transducer and activator of transcription. (849 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1181 aa)
	Y1Q_0013419	Uncharacterized protein. (77 aa)
	Y1Q_0012030	Gasdermin-A2-like. (524 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1182 aa)
	Y1Q_0013534	NACHT, LRR and PYD domains-containing protein 3-like. (739 aa)
	Y1Q_0013331	Protein S100; Belongs to the S-100 family. (100 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	VWC2	Brorin. (265 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	UBE2V1	UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa)
	Y1Q_0006366	Pyrin domain-containing protein. (469 aa)
	NLRP3	NACHT, LRR and PYD domains-containing protein 12. (901 aa)
	Y1Q_0006330	Synaptotagmin-2-like. (234 aa)
	Y1Q_0006368	Ribonuclease inhibitor-like. (770 aa)
	IL1R2	Interleukin-1 receptor type 2. (409 aa)
	SIGIRR	Single Ig IL-1-related receptor isoform B. (561 aa)
	IL1R1	Interleukin-1 receptor type 1. (1039 aa)
	IL1RL1-1	Interleukin-1 receptor-like 1 isoform A. (548 aa)
	IL1RN	Interleukin-1. (177 aa)
	TONSLL	Tonsoku-like protein. (924 aa)
	TAB3	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (368 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	Y1Q_0000053	Ig-like domain-containing protein. (196 aa)
	IL1RAPL1	TIR domain-containing protein. (213 aa)
	SCARB1	Scavenger receptor class B member 1 isoform A. (959 aa)
	PSMB11	Proteasome subunit beta. (261 aa)
	CCDC71L-1	Coiled-coil domain-containing protein 71L isoform B. (79 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10. (226 aa)
	NFKB1	Nuclear factor NF-kappa-B p105 subunit isoform B. (1031 aa)
	PSME1	Proteasome activator complex subunit 1. (150 aa)
	UBE2N	Ubiquitin-conjugating enzyme E2 N. (112 aa)
	IKBIP	Inhibitor of nuclear factor kappa-B kinase-interacting protein. (334 aa)
	Y1Q_0011504	Uncharacterized protein. (742 aa)
	MAP3K2	Mitogen-activated protein kinase kinase kinase 2. (477 aa)
	MAP3K3	Mitogen-activated protein kinase kinase kinase 3. (674 aa)
	PELI1	E3 ubiquitin-ligase pellino-like protein 1. (397 aa)
	TONSL	Tonsoku-like protein. (412 aa)
	Y1Q_0022506	Uncharacterized protein. (167 aa)
	SQSTM1	Sequestosome-1. (457 aa)
	LRRC45	Leucine-rich repeat-containing protein 45. (777 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
	PSMA1	Proteasome subunit alpha type. (261 aa)
	PTPN5	Tyrosine-protein phosphatase non-receptor type 5. (448 aa)
	HPS5L	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (126 aa)
	TOLLIP	Toll-interacting protein. (274 aa)
	APP	BPTI/Kunitz inhibitor domain-containing protein. (743 aa)
	PSME4	Proteasome activator complex subunit 4. (1808 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	PELI1-2	Uncharacterized protein. (418 aa)
	IRAK2	Interleukin-1 receptor-associated kinase-like 2. (732 aa)
	LRRC74A	Leucine-rich repeat-containing protein 74A isoform A. (478 aa)
	Y1Q_0020759	Uncharacterized protein. (171 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform B. (626 aa)
	PSMB8	Proteasome subunit beta. (282 aa)
	PSMB9	Proteasome subunit beta. (216 aa)
	IL1RAP-1	Interleukin-1 receptor accessory protein isoform B. (852 aa)
	Y1Q_0001846	Uncharacterized protein. (71 aa)
	IL1BL	Interleukin-1. (280 aa)
	Y1Q_0001844	Interleukin-1. (129 aa)
	IL1B	Interleukin-1; Belongs to the IL-1 family. (448 aa)
	PTPN23	Tyrosine-protein phosphatase non-receptor type 23. (1589 aa)
	Y1Q_0012288	Uncharacterized protein. (180 aa)
	IKBKG	NF-kappa-B essential modulator. (542 aa)
	NLRC5	Protein NLRC5 isoform B. (1891 aa)
	NKIRAS1	NF-kappa-B inhibitor-interacting Ras-like protein 1. (192 aa)
	CARD8-2	Caspase recruitment domain-containing protein 8. (317 aa)
	N4BP1	NEDD4-binding protein 1. (938 aa)
	Y1Q_0021221	TMEM189_B_dmain domain-containing protein. (76 aa)
	Y1Q_0008580	Uncharacterized protein. (441 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7 isoform A. (610 aa)
	Y1Q_0013910	Uncharacterized protein. (179 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
	Y1Q_0018842	Uncharacterized protein. (192 aa)
	Y1Q_0018841	Ig-like domain-containing protein. (665 aa)
	Im:7160594	Major facilitator superfamily domain-containing protein 1. (511 aa)
	Y1Q_0020396	Uncharacterized protein. (1078 aa)
	Y1Q_0017347	NACHT, LRR and PYD domains-containing protein 3-like. (334 aa)
	VWC2L	Von Willebrand factor C domain-containing protein 2-like. (222 aa)
	MFSD1	Major facilitator superfamily domain-containing protein 1 isoform A. (520 aa)
	LRRC31	Leucine-rich repeat-containing protein 31. (587 aa)
	LRRC34	Leucine-rich repeat-containing protein 34. (417 aa)
	IKBKB-2	Uncharacterized protein. (757 aa)
	Y1Q_0020170	Pyrin domain-containing protein. (269 aa)
	Y1Q_0020172	NACHT, LRR and PYD domains-containing protein 12-like. (484 aa)
	Y1Q_0020171	Uncharacterized protein. (219 aa)
	IRAK1	Interleukin-1 receptor-associated kinase 1. (918 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase. (492 aa)
	NLRX1	NLR family member X1. (818 aa)
	IL18	Interleukin-18. (239 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (104 aa)
	TAB1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
	USP18	Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (359 aa)
	LRRC14	Leucine-rich repeat-containing protein 14. (511 aa)
	NFKBIA	NF-kappa-B inhibitor alpha. (299 aa)
	TAB2	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (276 aa)
	PSME2	Proteasome activator complex subunit 2. (242 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	MAP3K3-2	A0A151PDL2	A0A151PC36	3-ketoacyl-CoA thiolase, peroxisomal isoform B.	Uncharacterized protein.	0.900
ACAA1	SQSTM1	A0A151PDL2	A0A151M7D3	3-ketoacyl-CoA thiolase, peroxisomal isoform B.	Sequestosome-1.	0.681
ACAA1	TRAF6	A0A151PDL2	A0A151MBD1	3-ketoacyl-CoA thiolase, peroxisomal isoform B.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.767
APP	IL1BL	A0A151MDY4	A0A151MMB8	BPTI/Kunitz inhibitor domain-containing protein.	Interleukin-1.	0.455
APP	NFKB1	A0A151MDY4	A0A151NMD6	BPTI/Kunitz inhibitor domain-containing protein.	Nuclear factor NF-kappa-B p105 subunit isoform B.	0.482
APP	NFKB2	A0A151MDY4	A0A151PGF9	BPTI/Kunitz inhibitor domain-containing protein.	Uncharacterized protein.	0.482
BTRC	CUL1	A0A151MLH5	A0A151P2L7	F-box/WD repeat-containing protein 1A isoform B.	Cullin-1; Belongs to the cullin family.	0.995
BTRC	IKBKB	A0A151MLH5	A0A151PH37	F-box/WD repeat-containing protein 1A isoform B.	Inhibitor of nuclear factor kappa-B kinase subunit beta.	0.508
BTRC	IKBKB-2	A0A151MLH5	A0A151ND20	F-box/WD repeat-containing protein 1A isoform B.	Uncharacterized protein.	0.706
BTRC	KXD1	A0A151MLH5	A0A151NUA6	F-box/WD repeat-containing protein 1A isoform B.	KxDL motif-containing protein 1.	0.766
BTRC	MAP3K2	A0A151MLH5	A0A151M152	F-box/WD repeat-containing protein 1A isoform B.	Mitogen-activated protein kinase kinase kinase 2.	0.410
BTRC	NFKB1	A0A151MLH5	A0A151NMD6	F-box/WD repeat-containing protein 1A isoform B.	Nuclear factor NF-kappa-B p105 subunit isoform B.	0.659
BTRC	NFKB2	A0A151MLH5	A0A151PGF9	F-box/WD repeat-containing protein 1A isoform B.	Uncharacterized protein.	0.659
BTRC	NFKBIA	A0A151MLH5	A0A151NKE7	F-box/WD repeat-containing protein 1A isoform B.	NF-kappa-B inhibitor alpha.	0.987
BTRC	NFKBIB	A0A151MLH5	A0A151PIS4	F-box/WD repeat-containing protein 1A isoform B.	NF-kappa-B inhibitor beta.	0.692
BTRC	RBX1	A0A151MLH5	A0A151NHM4	F-box/WD repeat-containing protein 1A isoform B.	E3 ubiquitin-protein ligase RBX1.	0.976
BTRC	RPS27A	A0A151MLH5	A0A151MGG2	F-box/WD repeat-containing protein 1A isoform B.	Ubiquitin-40S ribosomal protein S27a.	0.768
BTRC	SCARB1	A0A151MLH5	A0A151NSC4	F-box/WD repeat-containing protein 1A isoform B.	Scavenger receptor class B member 1 isoform A.	0.745
BTRC	UBE2N	A0A151MLH5	A0A151LYX2	F-box/WD repeat-containing protein 1A isoform B.	Ubiquitin-conjugating enzyme E2 N.	0.529
CARD8-2	NLRP3	A0A151MRF7	A0A151NY81	Caspase recruitment domain-containing protein 8.	NACHT, LRR and PYD domains-containing protein 12.	0.900