STRINGSTRING
ELK1 ELK1 MAP2K3 MAP2K3 MAP2K6 MAP2K6 PPP2CB PPP2CB VRK3-1 VRK3-1 MAPK14 MAPK14 CREB1 CREB1 IRAK1 IRAK1 PPP4R1-2 PPP4R1-2 Y1Q_0008090 Y1Q_0008090 TAB1 TAB1 TAB2 TAB2 Y1Q_0019536 Y1Q_0019536 CCDC71L-1 CCDC71L-1 MAPK1 MAPK1 SCARB1 SCARB1 RPS6KA4 RPS6KA4 Y1Q_0020451 Y1Q_0020451 KXD1 KXD1 TAB3 TAB3 ATF7 ATF7 UBE2V1 UBE2V1 PPP4R1 PPP4R1 FOSL2 FOSL2 MAP2K4 MAP2K4 PPP4R4 PPP4R4 RPS6KA6 RPS6KA6 DUSP3 DUSP3 MAPK11 MAPK11 MAPK7 MAPK7 RIPK2 RIPK2 JUND JUND c-jun c-jun FNBP4 FNBP4 RIPK3L RIPK3L FOS FOS MAPK8 MAPK8 IRAK2 IRAK2 RPS27A RPS27A MAPKAPK3-2 MAPKAPK3-2 PPP2R1A PPP2R1A TRAF6 TRAF6 MAPKAPK3 MAPKAPK3 MAPK9 MAPK9 ATF2 ATF2 RPS6KA2 RPS6KA2 MAP2K7 MAP2K7 DUSP7 DUSP7 PPP2CA PPP2CA DUSP6 DUSP6 UBE2N UBE2N Y1Q_0011504 Y1Q_0011504 Y1Q_0013899 Y1Q_0013899 IKBKG IKBKG CREB5 CREB5 NOD1 NOD1 Y1Q_0021221 Y1Q_0021221 ATF1 ATF1 MAP3K7 MAP3K7 MAPK15 MAPK15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELK1ETS domain-containing protein Elk-1. (396 aa)
MAP2K3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (348 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
VRK3-1Inactive serine/threonine-protein kinase VRK3 isoform A. (407 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (918 aa)
PPP4R1-2WRNPLPNID domain-containing protein. (952 aa)
Y1Q_0008090LisH domain-containing protein. (1143 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (276 aa)
Y1Q_0019536Mitogen-activated protein kinase. (505 aa)
CCDC71L-1Coiled-coil domain-containing protein 71L isoform B. (79 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (887 aa)
Y1Q_0020451Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (281 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (368 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7. (482 aa)
UBE2V1UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (956 aa)
FOSL2Fos-related antigen 2. (253 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform A; Belongs to the protein kinase superfamily. (394 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform A. (864 aa)
RPS6KA6Ribosomal protein S6 kinase. (820 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (675 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (561 aa)
JUNDBZIP domain-containing protein. (87 aa)
c-junTranscription factor AP-1; Belongs to the bZIP family. (320 aa)
FNBP4Formin-binding protein 4 isoform B. (904 aa)
RIPK3LReceptor-interacting serine/threonine-protein kinase 2. (564 aa)
FOSProto-oncogene c-Fos isoform A. (530 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
IRAK2Interleukin-1 receptor-associated kinase-like 2. (732 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
MAPKAPK3-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (387 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (354 aa)
MAPK9Mitogen-activated protein kinase. (430 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (458 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform C. (488 aa)
DUSP7Dual specificity protein phosphatase 7. (289 aa)
PPP2CASerine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
UBE2NUbiquitin-conjugating enzyme E2 N. (112 aa)
Y1Q_0011504Uncharacterized protein. (742 aa)
Y1Q_0013899Uncharacterized protein. (103 aa)
IKBKGNF-kappa-B essential modulator. (542 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (552 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (951 aa)
Y1Q_0021221TMEM189_B_dmain domain-containing protein. (76 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (330 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform A. (610 aa)
MAPK15Mitogen-activated protein kinase. (807 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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