23 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAK3	Non-specific serine/threonine protein kinase. (526 aa)
	ARVCF	Uncharacterized protein. (918 aa)
	CTNND1	Catenin delta-1 isoform B. (996 aa)
	CTNNB1	Catenin beta-1 isoform B. (783 aa)
	JUP	Uncharacterized protein. (718 aa)
	Y1Q_0017424	Uncharacterized protein. (235 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	STX12	Syntaxin-12; Belongs to the syntaxin family. (269 aa)
	C1GALT1A	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A. (432 aa)
	AKT2	Non-specific serine/threonine protein kinase. (270 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	PAK2-2	Non-specific serine/threonine protein kinase. (741 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1. (515 aa)
	AKT3-2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	VAV2	Uncharacterized protein. (839 aa)
	VAV3-2	Uncharacterized protein. (846 aa)
	PAK2	Non-specific serine/threonine protein kinase. (546 aa)
	STX7	Syntaxin-7; Belongs to the syntaxin family. (274 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	RICTOR	Rapamycin-insensitive companion of mTOR. (1439 aa)
	PRR5	Proline-rich protein 5 isoform B. (468 aa)
	CDH5	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (733 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (815 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	AKT3	A0A151MPY5	A0A151M239	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	AKT3-2	A0A151MPY5	A0A151MH49	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	CTNNB1	A0A151MPY5	A0A151P2N9	Non-specific serine/threonine protein kinase.	Catenin beta-1 isoform B.	0.586
AKT2	JUP	A0A151MPY5	A0A151PC76	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.537
AKT2	PDPK1	A0A151MPY5	A0A151MHZ4	Non-specific serine/threonine protein kinase.	3-phosphoinositide-dependent protein kinase 1.	0.851
AKT2	RICTOR	A0A151MPY5	A0A151MWZ3	Non-specific serine/threonine protein kinase.	Rapamycin-insensitive companion of mTOR.	0.784
AKT2	Y1Q_0017424	A0A151MPY5	A0A151PCN9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.899
AKT3	AKT2	A0A151M239	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3	AKT3-2	A0A151M239	A0A151MH49	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT3	CTNNB1	A0A151M239	A0A151P2N9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Catenin beta-1 isoform B.	0.586
AKT3	JUP	A0A151M239	A0A151PC76	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.537
AKT3	PDPK1	A0A151M239	A0A151MHZ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide-dependent protein kinase 1.	0.842
AKT3	RICTOR	A0A151M239	A0A151MWZ3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Rapamycin-insensitive companion of mTOR.	0.784
AKT3-2	AKT2	A0A151MH49	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3-2	AKT3	A0A151MH49	A0A151M239	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT3-2	CTNNB1	A0A151MH49	A0A151P2N9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Catenin beta-1 isoform B.	0.586
AKT3-2	JUP	A0A151MH49	A0A151PC76	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.537
AKT3-2	PDPK1	A0A151MH49	A0A151MHZ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide-dependent protein kinase 1.	0.842
AKT3-2	RICTOR	A0A151MH49	A0A151MWZ3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Rapamycin-insensitive companion of mTOR.	0.784
ARVCF	CDH5	A0A151NRN7	A0A151N7C5	Uncharacterized protein.	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	0.790