45 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HIST1H2B5L	Histone H2B; Belongs to the histone H2B family. (126 aa)
	DDX50	Nucleolar RNA helicase 2. (692 aa)
	POLR2L-1	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (104 aa)
	HIST1H4D	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	H2AFV	Histone H2A; Belongs to the histone H2A family. (128 aa)
	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1053 aa)
	H2AFZ	Histone H2A; Belongs to the histone H2A family. (128 aa)
	POLR2L-2	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (74 aa)
	Y1Q_0016099	Histone H2B; Belongs to the histone H2B family. (126 aa)
	Y1Q_0024039	KIX domain-containing protein. (131 aa)
	POLR2F	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
	CREBBP	CREB-binding protein isoform C. (2208 aa)
	POLR1E	DNA-directed RNA polymerase I subunit RPA49. (417 aa)
	SF3B1	Splicing factor 3B subunit 1. (1301 aa)
	BAZ1B	Tyrosine-protein kinase BAZ1B. (1489 aa)
	Y1Q_0020098	Histone H2B; Belongs to the histone H2B family. (166 aa)
	HIST2H2BE	Histone H2B; Belongs to the histone H2B family. (126 aa)
	HIST1H2BF	Histone H2B; Belongs to the histone H2B family. (126 aa)
	TBPL2	TATA box-binding protein-like protein 2. (331 aa)
	TBP	TATA-box-binding protein. (301 aa)
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (161 aa)
	ZNRD1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	SMARCA5-2	Uncharacterized protein. (1027 aa)
	POLR1B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1078 aa)
	GSK3B-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
	POLR1C	DNA-directed RNA polymerases I and III subunit RPAC1. (346 aa)
	ERCC6	DNA excision repair protein ERCC-6. (1491 aa)
	MYO1C	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (977 aa)
	Y1Q_0021955	Unconventional myosin-Ic-like. (117 aa)
	DEK	Protein DEK. (367 aa)
	TWISTNB	DNA-directed RNA polymerase I subunit RPA43. (317 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (783 aa)
	CD3EAP	DNA-directed RNA polymerase I subunit RPA34. (226 aa)
	TAF1C	TATA box-binding protein-associated factor RNA polymerase I subunit C. (117 aa)
	GSK3B	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (413 aa)
	MYBBP1A	Myb-binding protein 1A. (1143 aa)
	TAF1B	TATA box-binding protein-associated factor RNA polymerase I subunit B. (592 aa)
	Y1Q_0012805	Histone H2B; Belongs to the histone H2B family. (118 aa)
	DHX58	Putative ATP-dependent RNA helicase DHX58 isoform E; Belongs to the small heat shock protein (HSP20) family. (1743 aa)
	Y1Q_0018383	Histone H2B-like; Belongs to the histone H2B family. (152 aa)
	POLR1A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1689 aa)
	TAF1A-1	TATA box-binding protein-associated factor RNA polymerase I subunit A isoform B. (454 aa)
	TAF1D	TATA box-binding protein-associated factor RNA polymerase I subunit D. (330 aa)
	POLR2E	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (231 aa)
	DDX50-2	Uncharacterized protein. (684 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAZ1B	CD3EAP	A0A151N9J8	A0A151MYN9	Tyrosine-protein kinase BAZ1B.	DNA-directed RNA polymerase I subunit RPA34.	0.455
BAZ1B	CREBBP	A0A151N9J8	A0A151NHH3	Tyrosine-protein kinase BAZ1B.	CREB-binding protein isoform C.	0.545
BAZ1B	DDX50	A0A151N9J8	A0A151P006	Tyrosine-protein kinase BAZ1B.	Nucleolar RNA helicase 2.	0.677
BAZ1B	DDX50-2	A0A151N9J8	A0A151P008	Tyrosine-protein kinase BAZ1B.	Uncharacterized protein.	0.677
BAZ1B	DEK	A0A151N9J8	A0A151MP67	Tyrosine-protein kinase BAZ1B.	Protein DEK.	0.740
BAZ1B	DHX58	A0A151N9J8	A0A151PCM0	Tyrosine-protein kinase BAZ1B.	Putative ATP-dependent RNA helicase DHX58 isoform E; Belongs to the small heat shock protein (HSP20) family.	0.527
BAZ1B	ERCC6	A0A151N9J8	A0A151MKX5	Tyrosine-protein kinase BAZ1B.	DNA excision repair protein ERCC-6.	0.775
BAZ1B	GSK3B	A0A151N9J8	A0A151N132	Tyrosine-protein kinase BAZ1B.	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily.	0.436
BAZ1B	GSK3B-2	A0A151N9J8	A0A151MD62	Tyrosine-protein kinase BAZ1B.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.436
BAZ1B	H2AFV	A0A151N9J8	A0A151NP39	Tyrosine-protein kinase BAZ1B.	Histone H2A; Belongs to the histone H2A family.	0.504
BAZ1B	H2AFZ	A0A151N9J8	A0A151NMC8	Tyrosine-protein kinase BAZ1B.	Histone H2A; Belongs to the histone H2A family.	0.504
BAZ1B	HIST1H4D	A0A151N9J8	A0A151NSZ8	Tyrosine-protein kinase BAZ1B.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.612
BAZ1B	KAT2B	A0A151N9J8	A0A151MQU0	Tyrosine-protein kinase BAZ1B.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.527
BAZ1B	MYBBP1A	A0A151N9J8	A0A151N5H9	Tyrosine-protein kinase BAZ1B.	Myb-binding protein 1A.	0.773
BAZ1B	MYO1C	A0A151N9J8	A0A151MLE5	Tyrosine-protein kinase BAZ1B.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.648
BAZ1B	POLR1B	A0A151N9J8	A0A151MCN9	Tyrosine-protein kinase BAZ1B.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.602
BAZ1B	POLR1C	A0A151N9J8	A0A151MHQ6	Tyrosine-protein kinase BAZ1B.	DNA-directed RNA polymerases I and III subunit RPAC1.	0.602
BAZ1B	POLR1E	A0A151N9J8	A0A151NDY5	Tyrosine-protein kinase BAZ1B.	DNA-directed RNA polymerase I subunit RPA49.	0.723
BAZ1B	POLR2F	A0A151N9J8	A0A151NHP8	Tyrosine-protein kinase BAZ1B.	DNA-directed RNA polymerases I, II, and III subunit RPABC2.	0.600
BAZ1B	SF3B1	A0A151N9J8	A0A151N9Z7	Tyrosine-protein kinase BAZ1B.	Splicing factor 3B subunit 1.	0.724