STRINGSTRING
XIAP XIAP CASP14-2 CASP14-2 DBNL DBNL CAPG CAPG APC APC NAIP NAIP Y1Q_0004030 Y1Q_0004030 CHMP4C CHMP4C CLSPN CLSPN RIPK3 RIPK3 APC2 APC2 Y1Q_0012433 Y1Q_0012433 NMT1 NMT1 MAPT-1 MAPT-1 PRKCD PRKCD HMGB2 HMGB2 CASP3 CASP3 IRF2 IRF2 Y1Q_0021348 Y1Q_0021348 CHMP3 CHMP3 BIRC2 BIRC2 CHMP4B CHMP4B TNFRSF10B TNFRSF10B CHMP7-1 CHMP7-1 Y1Q_0012030 Y1Q_0012030 GSDMA GSDMA CHMP2A CHMP2A BAK1 BAK1 CHMP6 CHMP6 CTNNB1 CTNNB1 PDCD6IP PDCD6IP UNC5B UNC5B FAS FAS BIRC7-1 BIRC7-1 Y1Q_0004491 Y1Q_0004491 LMNTD2 LMNTD2 DAPK3 DAPK3 CASP7 CASP7 OPA1 OPA1 KXD1 KXD1 SEPT4 SEPT4 CASP1 CASP1 OGT OGT DIABLO DIABLO SCARB1 SCARB1 SEPT5 SEPT5 STK24 STK24 Y1Q_0019911 Y1Q_0019911 CD14 CD14 ACIN1-1 ACIN1-1 PRKCQ PRKCQ BCAP29 BCAP29 SFN SFN TTC6 TTC6 BAX BAX Y1Q_0008411 Y1Q_0008411 Y1Q_0017176 Y1Q_0017176 BID BID DNM1L DNM1L APPL2 APPL2 H1F0 H1F0 IL18 IL18 RIPK1 RIPK1 ROCK1 ROCK1 FNTA FNTA Y1Q_0014883 Y1Q_0014883 TJP2 TJP2 LMNB1 LMNB1 CFLAR CFLAR MAP2-1 MAP2-1 PKP1 PKP1 YWHAQ YWHAQ STK26 STK26 HMGB3 HMGB3 STUB1 STUB1 DYNLL2 DYNLL2 YWHAG YWHAG Y1Q_0018846 Y1Q_0018846 DYNLL1 DYNLL1 Y1Q_0012019 Y1Q_0012019 YWHAH YWHAH DFFA DFFA DFFB DFFB FLOT1 FLOT1 APPL1 APPL1 YWHAZ YWHAZ DCC DCC AVEN AVEN BMF BMF NPVF NPVF Y1Q_0019264 Y1Q_0019264 DFNA5 DFNA5 SCIN SCIN Y1Q_0005053 Y1Q_0005053 LMNTD1-1 LMNTD1-1 DSG1 DSG1 DSG2 DSG2 LY96 LY96 Y1Q_0003728 Y1Q_0003728 IL1B IL1B Y1Q_0001844 Y1Q_0001844 IL1BL IL1BL TRADD TRADD NEO1 NEO1 H1FOO H1FOO STK25 STK25 BOK BOK CASP9 CASP9 CASP6 CASP6 BCAP31 BCAP31 BCL2L1 BCL2L1 PELI1-2 PELI1-2 RPS27A RPS27A GSN GSN SH3GLB2 SH3GLB2 SPTA1 SPTA1 TLR4 TLR4 CHMP2B CHMP2B FILIP1L-2 FILIP1L-2 TNFRSFA TNFRSFA GAS2 GAS2 APIP APIP FLOT2 FLOT2 Y1Q_0001619 Y1Q_0001619 Y1Q_0001622 Y1Q_0001622 TJP1-2 TJP1-2 DAPK2 DAPK2 NR13 NR13 LMNA LMNA PRTG PRTG MDP1 MDP1 TJP1 TJP1 DAPK1 DAPK1 LMNAL LMNAL IRF1 IRF1 TNFSF10 TNFSF10 UBE2L3 UBE2L3 SH3GLB1 SH3GLB1 OMA1 OMA1 BCL2L11-1 BCL2L11-1 KPNA1 KPNA1 Y1Q_0011460 Y1Q_0011460 APAF1 APAF1 HIST1H1T HIST1H1T Y1Q_0020094 Y1Q_0020094 HIST1H110 HIST1H110 TMEM198 TMEM198
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XIAPE3 ubiquitin-protein ligase XIAP. (558 aa)
CASP14-2Uncharacterized protein; Belongs to the peptidase C14A family. (249 aa)
DBNLDrebrin-like protein isoform B. (481 aa)
CAPGMacrophage-capping protein. (369 aa)
APCAdenomatous polyposis coli protein. (2841 aa)
NAIPBaculoviral IAP repeat-containing protein 1 isoform A. (878 aa)
Y1Q_0004030Uncharacterized protein. (147 aa)
CHMP4CCharged multivesicular body protein 4c. (221 aa)
CLSPNClaspin. (1316 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3. (508 aa)
APC2Uncharacterized protein. (2467 aa)
Y1Q_0012433Death-associated protein kinase 2; Belongs to the protein kinase superfamily. (409 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (495 aa)
MAPT-1Microtubule-associated protein. (573 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
HMGB2High mobility group protein B2. (271 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (292 aa)
IRF2Interferon regulatory factor 2 isoform B. (446 aa)
Y1Q_0021348Aldolase_II domain-containing protein. (867 aa)
CHMP3Charged multivesicular body protein 3. (220 aa)
BIRC2Inhibitor of apoptosis protein. (493 aa)
CHMP4BCharged multivesicular body protein 4b. (211 aa)
TNFRSF10BTumor necrosis factor receptor superfamily member 10B. (394 aa)
CHMP7-1Charged multivesicular body protein 7 isoform A. (398 aa)
Y1Q_0012030Gasdermin-A2-like. (524 aa)
GSDMAGasdermin-A. (671 aa)
CHMP2ACharged multivesicular body protein 2a. (220 aa)
BAK1Bcl-2-like proteinous antagonist/killer. (222 aa)
CHMP6Charged multivesicular body protein 6. (187 aa)
CTNNB1Catenin beta-1 isoform B. (783 aa)
PDCD6IPProgrammed cell death 6-interacting protein. (820 aa)
UNC5BUncharacterized protein. (949 aa)
FASTumor necrosis factor receptor superfamily member 6. (341 aa)
BIRC7-1Baculoviral IAP repeat-containing protein 7 isoform A. (309 aa)
Y1Q_0004491Lamin-A; Belongs to the intermediate filament family. (1098 aa)
LMNTD2Lamin tail domain-containing protein 2 isoform A. (718 aa)
DAPK3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (456 aa)
CASP7Caspase-7; Belongs to the peptidase C14A family. (319 aa)
OPA1Dynamin-like protein, mitochondrial isoform A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (905 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
SEPT4Septin-4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (466 aa)
CASP1Caspase-1; Belongs to the peptidase C14A family. (395 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase subunit isoform B. (1075 aa)
DIABLODiablo-like protein, mitochondrial. (190 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
SEPT5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (579 aa)
STK24Protein kinase domain-containing protein. (431 aa)
Y1Q_0019911Drebrin-like. (419 aa)
CD14Monocyte differentiation antigen CD14. (461 aa)
ACIN1-1Apoptotic chromatin condensation inducer in the nucleus isoform B. (783 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (751 aa)
BCAP29B-cell receptor-associated protein 29. (245 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (246 aa)
TTC6Tetratricopeptide repeat protein 6 isoform C. (1556 aa)
BAXApoptosis regulator BAX. (209 aa)
Y1Q_0008411Apoptosis regulator BAX-like. (187 aa)
Y1Q_0017176Bap31 domain-containing protein. (114 aa)
BIDBH3-interacting domain death agonist. (137 aa)
DNM1LDynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa)
APPL2Uncharacterized protein. (659 aa)
H1F0Histone H5. (187 aa)
IL18Interleukin-18. (239 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (699 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
FNTAProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha isoform B. (380 aa)
Y1Q_0014883Transmembrane protein 198-like. (343 aa)
TJP2Tight junction protein ZO-2 isoform B; Belongs to the MAGUK family. (1039 aa)
LMNB1Lamin-B1; Belongs to the intermediate filament family. (591 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (530 aa)
MAP2-1Microtubule-associated protein. (1922 aa)
PKP1Plakophilin-1 isoform A. (731 aa)
YWHAQ14-3-3 protein theta; Belongs to the 14-3-3 family. (267 aa)
STK26Serine/threonine-protein kinase 26. (416 aa)
HMGB3High mobility group protein B3. (280 aa)
STUB1E3 ubiquitin-protein ligase CHIP isoform A. (339 aa)
DYNLL2Dynein light chain. (77 aa)
YWHAG14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
Y1Q_0018846Uncharacterized protein. (422 aa)
DYNLL1Dynein light chain. (123 aa)
Y1Q_0012019Uncharacterized protein. (105 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (247 aa)
DFFADNAation factor subunit alpha. (328 aa)
DFFBDNAation factor subunit beta. (333 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (501 aa)
APPL1DCC-interacting protein 13-alpha. (708 aa)
YWHAZ14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (319 aa)
DCCNetrin receptor DCC isoform B. (1436 aa)
AVENCell death regulator Aven. (276 aa)
BMFBcl-2-modifying factor. (217 aa)
NPVFPro-FMRFamide-related neuropeptide VF. (159 aa)
Y1Q_0019264Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (129 aa)
DFNA5Non-syndromic hearing impairment protein 5. (486 aa)
SCINAdseverin. (717 aa)
Y1Q_0005053Uncharacterized protein. (172 aa)
LMNTD1-1Lamin tail domain-containing protein 1 isoform A. (321 aa)
DSG1Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1032 aa)
DSG2Desmoglein-2. (1142 aa)
LY96Lymphocyte antigen 96. (131 aa)
Y1Q_0003728Uncharacterized protein. (100 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (448 aa)
Y1Q_0001844Interleukin-1. (129 aa)
IL1BLInterleukin-1. (280 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (336 aa)
NEO1Uncharacterized protein. (1428 aa)
H1FOOHistone H1oo. (313 aa)
STK25Serine/threonine-protein kinase 25. (433 aa)
BOKBcl-2-related ovarian killer protein. (199 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (423 aa)
CASP6Caspase-6; Belongs to the peptidase C14A family. (302 aa)
BCAP31B-cell receptor-associated protein 31. (144 aa)
BCL2L1Bcl-2-like protein 1. (281 aa)
PELI1-2Uncharacterized protein. (418 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
GSNUncharacterized protein. (762 aa)
SH3GLB2Endophilin-B2. (405 aa)
SPTA1Spectrin alpha chain, erythrocytic 1 isoform B. (3247 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
CHMP2BCharged multivesicular body protein 2b. (214 aa)
FILIP1L-2CortBP2 domain-containing protein. (1024 aa)
TNFRSFATumor necrosis factor receptor superfamily member 6-like. (427 aa)
GAS2Growth arrest-specific protein 2. (280 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (240 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (451 aa)
Y1Q_0001619ZU5 domain-containing protein. (497 aa)
Y1Q_0001622Uncharacterized protein. (71 aa)
TJP1-2Uncharacterized protein; Belongs to the MAGUK family. (1154 aa)
DAPK2Death-associated protein kinase 2 isoform B; Belongs to the protein kinase superfamily. (447 aa)
NR13Anti-apoptotic protein NR13. (76 aa)
LMNALamin-L(III)-like; Belongs to the intermediate filament family. (625 aa)
PRTGProtogenin. (1310 aa)
MDP1Magnesium-dependent phosphatase 1. (160 aa)
TJP1Tight junction protein ZO-1 isoform A; Belongs to the MAGUK family. (1182 aa)
DAPK1Death-associated protein kinase 1. (1431 aa)
LMNALLamin; Belongs to the intermediate filament family. (587 aa)
IRF1Interferon regulatory factor 1 isoform A. (430 aa)
TNFSF10Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (295 aa)
UBE2L3Ubiquitin-conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
SH3GLB1Endophilin-B1 isoform B. (524 aa)
OMA1Metalloendopeptidase OMA1, mitochondrial. (504 aa)
BCL2L11-1Bcl-2-like protein 11 isoform C. (178 aa)
KPNA1Importin subunit alpha; Belongs to the importin alpha family. (515 aa)
Y1Q_0011460Uncharacterized protein. (103 aa)
APAF1Apoptotic protease-activating factor 1. (1276 aa)
HIST1H1THistone H1t. (203 aa)
Y1Q_0020094Histone H1.01-like. (168 aa)
HIST1H110Histone H1.10. (124 aa)
TMEM198Transmembrane protein 198. (250 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (30%) [HD]