163 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMC1	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
	PSMA1	Proteasome subunit alpha type. (261 aa)
	Y1Q_0000685	Tubby-like protein; Belongs to the TUB family. (523 aa)
	GAS8	Growth arrest-specific protein 8. (458 aa)
	GPR161	G-protein coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (489 aa)
	BOC	Brother of CDO. (1192 aa)
	GSK3B-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
	IFT57	Intraflagellar transport 57-like protein. (390 aa)
	PSMD5-1	26S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
	PSMB7	Proteasome subunit beta. (274 aa)
	ERLEC1	Endoplasmic reticulum lectin 1. (537 aa)
	PSME4	Proteasome activator complex subunit 4. (1808 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	SEL1L2	Uncharacterized protein. (658 aa)
	Y1Q_0013291	Death ligand signal enhancer. (483 aa)
	ADCY10	Adenylate cyclase type 10 isoform C. (1746 aa)
	IFT122	Intraflagellar transport 122-like protein. (1184 aa)
	Y1Q_0023772	Uncharacterized protein. (599 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6. (348 aa)
	PRKAR2A	cAMP-dependent protein kinase type II-alpha regulatory subunit. (355 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform B. (626 aa)
	PSMB8	Proteasome subunit beta. (282 aa)
	PSMB9	Proteasome subunit beta. (216 aa)
	GLI1	Zinc finger protein GLI1. (476 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1074 aa)
	RPGRIP1L	Protein fantom. (1273 aa)
	NUMBL	PID domain-containing protein. (157 aa)
	ADCY6	Uncharacterized protein. (1272 aa)
	DISP2	Dispatched-like protein 2 isoform A. (973 aa)
	NUMB	Numb-like protein isoform A. (629 aa)
	Y1Q_0019558	Protein OS-9-like. (118 aa)
	Y1Q_0005328	Cyclic nucleotide-binding domain-containing protein. (578 aa)
	OS9	Protein OS-9. (461 aa)
	ARRB2	Arrestin_C domain-containing protein. (407 aa)
	P4HB	Protein disulfide-isomerase. (512 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
	Y1Q_0005128	Proteasome subunit beta. (277 aa)
	OFD1	Oral-facial-digital syndrome 1 protein isoform B. (1020 aa)
	FUZ	Fuzzy-like protein isoform A. (439 aa)
	GSK3B	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (413 aa)
	FOPNL	LisH domain-containing protein FOPNL. (175 aa)
	Y1Q_0008226	Uncharacterized protein. (490 aa)
	SMURF1	E3 ubiquitin-protein ligase. (732 aa)
	PRKAR1B	Uncharacterized protein. (413 aa)
	IQCE	IQ domain-containing protein E. (748 aa)
	PSMD12	26S proteasome non-ATPase regulatory subunit 12. (441 aa)
	PRKAR1A	cAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)
	SMURF2	E3 ubiquitin-protein ligase. (786 aa)
	PTCHD2	Patched domain-containing protein 2 isoform A. (1339 aa)
	ADCY9	Adenylate cyclase type 9 isoform B; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (993 aa)
	IFT140	Intraflagellar transport 140-like protein isoform B. (1483 aa)
	Y1Q_0019034	RPN1_C domain-containing protein. (356 aa)
	TULP1	Tubby-like protein; Belongs to the TUB family. (430 aa)
	MKS1	Meckel syndrome type 1 protein isoform B. (559 aa)
	Y1Q_0014893	Uncharacterized protein. (172 aa)
	CNBD2-1	Cyclic nucleotide-binding domain-containing protein 2 isoform B. (591 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMC5	Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
	CUL3	Cullin-3; Belongs to the cullin family. (768 aa)
	IFT172	Intraflagellar transport 172-like protein. (1389 aa)
	ADCY2-2	Guanylate cyclase domain-containing protein. (226 aa)
	THAP1	THAP domain-containing protein 1. (169 aa)
	CDON	Cell adhesion molecule-related/down-regulated by oncogenes. (1256 aa)
	DZIP1L	Zinc finger protein DZIP1L isoform C. (1022 aa)
	PSMC4	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (104 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily. (368 aa)
	EFCAB7	EF-hand calcium-binding domain-containing protein 7. (611 aa)
	TULP2	Tubby-related protein 2; Belongs to the TUB family. (526 aa)
	PSMA6	Proteasome subunit alpha type. (252 aa)
	Y1Q_0006499	Uncharacterized protein; Belongs to the protein kinase superfamily. (401 aa)
	HHIP	Hedgehog-interacting protein isoform A. (683 aa)
	ARR3	Arrestin-C isoform B. (428 aa)
	CDC73	Parafibromin. (531 aa)
	PSME2	Proteasome activator complex subunit 2. (242 aa)
	PSME1	Proteasome activator complex subunit 1. (150 aa)
	Y1Q_0019461	Uncharacterized protein. (120 aa)
	THAP7-1	THAP domain-containing protein 8 isoform A. (758 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10. (226 aa)
	ARR3-2	Arrestin_C domain-containing protein. (394 aa)
	Y1Q_0015615	Uncharacterized protein. (89 aa)
	PSMD7	26S proteasome non-ATPase regulatory subunit 7. (322 aa)
	PRKAR2B	cAMP-dependent protein kinase type II-beta regulatory subunit isoform B. (408 aa)
	SMO	Smoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family. (804 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	PSMB11	Proteasome subunit beta. (261 aa)
	PSMB5	Proteasome subunit beta type-5. (211 aa)
	DZIP1	Zinc finger protein DZIP1 isoform C. (815 aa)
	PSMD9-1	26S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
	SCARB1	Scavenger receptor class B member 1 isoform A. (959 aa)
	PSMB6	Proteasome subunit beta. (227 aa)
	VCP	Uncharacterized protein; Belongs to the AAA ATPase family. (880 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	SUFU	Suppressor of fused homolog. (469 aa)
	PSMD13	26S proteasome non-ATPase regulatory subunit 13. (376 aa)
	IFT52	Intraflagellar transport 52-like protein. (441 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	ITCH-2	E3 ubiquitin-protein ligase. (832 aa)
	ADCY3-2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (119 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
	GLI3	Uncharacterized protein. (1572 aa)
	PSMF1	Proteasome inhibitor PI31 subunit. (273 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	DISP1	Dispatched-like protein 1. (534 aa)
	HHAT	Protein-cysteine N-palmitoyltransferase HHAT; Belongs to the membrane-bound acyltransferase family. (487 aa)
	ADCY10-2	Adenylate cyclase type 10-like. (1672 aa)
	PSMD3	26S proteasome non-ATPase regulatory subunit 3. (521 aa)
	PSMB3	Proteasome subunit beta. (205 aa)
	SPOP-2	Uncharacterized protein. (400 aa)
	PDIA2	Protein disulfide-isomerase. (539 aa)
	Y1Q_0016804	Uncharacterized protein. (155 aa)
	IFT88	Intraflagellar transport 88-like protein. (817 aa)
	DYNC2H1	Uncharacterized protein. (4284 aa)
	Y1Q_0014655	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1059 aa)
	DHH	Desert hedgehog protein. (359 aa)
	PSMD2	26S proteasome non-ATPase regulatory subunit 2. (513 aa)
	ULK3	Serine/threonine-protein kinase ULK3 isoform B. (786 aa)
	EVC	Ellis-van Creveld syndrome protein isoform A. (995 aa)
	EVC2	Limbin isoform B. (1247 aa)
	SEL1L3	Sel-1-like protein 3. (1070 aa)
	Y1Q_0021608	Cyclic nucleotide-binding domain-containing protein. (327 aa)
	LRP2BP-1	LRP2-binding protein isoform B. (322 aa)
	Y1Q_0021609	Uncharacterized protein. (110 aa)
	WDR19	WD repeat-containing protein 19 isoform A. (1423 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (518 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (435 aa)
	HHATL	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Belongs to the membrane-bound acyltransferase family. (503 aa)
	TTC21A	Uncharacterized protein. (1316 aa)
	CCDC13	Coiled-coil domain-containing protein 13 isoform A. (661 aa)
	Y1Q_0014584	Uncharacterized protein. (90 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
	SPATA5	Spermatogenesis-associated protein 5. (871 aa)
	INTU	Protein inturned isoform B. (921 aa)
	Y1Q_0015744	Intraflagellar transport 172-like protein. (385 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (959 aa)
	Y1Q_0022623	SWIM-type domain-containing protein. (573 aa)
	WDR35	WD repeat-containing protein 35. (1186 aa)
	PSMD8	26S proteasome non-ATPase regulatory subunit 8. (257 aa)
	HYKK	Proteasome endopeptidase complex. (600 aa)
	SPATA5L1	Spermatogenesis-associated protein 5-like protein 1. (763 aa)
	GLIS3	Zinc finger protein GLIS3. (567 aa)
	PTCH1	Patched-like protein 1. (1479 aa)
	GAS1	Growth arrest-specific protein 1. (113 aa)
	KIF3B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (703 aa)
	CSNK1A1	Casein kinase I isoform C; Belongs to the protein kinase superfamily. (365 aa)
	Y1Q_0020706	Uncharacterized protein. (294 aa)
	SEL1L	Sel-1-like protein 1. (791 aa)
	PSMD4	26S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
	GLIS1	Zinc finger protein GLIS1 isoform B. (784 aa)
	Y1Q_0019052	NumbF domain-containing protein. (153 aa)
	PSMB1	Proteasome subunit beta. (240 aa)
	PDCD2	Programmed cell death protein 2. (311 aa)
	PSMA3	Proteasome subunit alpha type. (256 aa)
	GLI2	Zinc finger protein GLI2. (1511 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1017 aa)
	SPOP	Speckle-type POZ protein. (392 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14. (460 aa)
	TTC21B	Tetratricopeptide repeat protein 21B. (1317 aa)
	NOTUM	Palmitoleoyl-protein carboxylesterase NOTUM. (395 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	A0A151P235	A0A151PGT0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.449
ADCY1	ADCY2-2	A0A151P235	A0A151NCX3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein.	0.429
ADCY1	ADCY3	A0A151P235	A0A151M126	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.459
ADCY1	ADCY3-2	A0A151P235	A0A151P1B5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.948
ADCY1	ADCY6	A0A151P235	A0A151MUF3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.460
ADCY1	ADCY7	A0A151P235	A0A151MRZ2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.455
ADCY1	ADCY9	A0A151P235	A0A151N6G1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9 isoform B; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.674
ADCY1	PRKACB	A0A151P235	A0A151NJ28	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily.	0.961
ADCY1	PTRHD1	A0A151P235	A0A151P1V8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.509
ADCY1	Y1Q_0006499	A0A151P235	A0A151NKT3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.961
ADCY1	Y1Q_0014655	A0A151P235	A0A151P8F6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.606
ADCY1	Y1Q_0015615	A0A151P235	A0A151NNY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.429
ADCY2	ADCY1	A0A151PGT0	A0A151P235	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.449
ADCY2	ADCY3	A0A151PGT0	A0A151M126	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.638
ADCY2	ADCY6	A0A151PGT0	A0A151MUF3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.640
ADCY2	ADCY9	A0A151PGT0	A0A151N6G1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9 isoform B; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.576
ADCY2	PRKACB	A0A151PGT0	A0A151NJ28	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily.	0.930
ADCY2	PSMA1	A0A151PGT0	A0A151MC38	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Proteasome subunit alpha type.	0.404
ADCY2	Y1Q_0006499	A0A151PGT0	A0A151NKT3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.930
ADCY2	Y1Q_0014655	A0A151PGT0	A0A151P8F6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458