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| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (392 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa) |
| | ZNF385B | Zinc finger protein 385B isoform B. (505 aa) |
| | TBPL2 | TATA box-binding protein-like protein 2. (331 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TBP | TATA-box-binding protein. (301 aa) |
| | TAF5L | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor subunit 5L. (576 aa) |
| | L3MBTL1-1 | Lethal(3)malignant brain tumor-like protein 1. (844 aa) |
| | TBPL1 | TATA box-binding protein-like protein 1. (255 aa) |
| | TTC5 | Tetratricopeptide repeat protein 5. (439 aa) |
| | TMEM55B | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (208 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (527 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | CCNG1 | Cyclin-G1; Belongs to the cyclin family. (256 aa) |
| | POU4F3-1 | POU domain protein. (337 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa) |
| | RAD50 | DNA repair protein RAD50. (1448 aa) |
| | RMI1 | RecQ-mediated genome instability protein 1. (524 aa) |
| | PML | Protein PML isoform B. (586 aa) |
| | DYRK3 | Protein kinase domain-containing protein. (581 aa) |
| | NUAK2 | Protein kinase domain-containing protein. (615 aa) |
| | MDM4 | Protein Mdm4. (513 aa) |
| | EXD2 | Exonuclease 3'-5' domain-containing protein 2 isoform A. (621 aa) |
| | Y1Q_0000620 | Protein kinase domain-containing protein. (901 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa) |
| | CHD3 | Chromodomain-helicase-DNA-binding protein 3. (1920 aa) |
| | TAF13 | Transcription initiation factor TFIID subunit 13. (124 aa) |
| | EHMT2 | Histone-lysine N-methyltransferase EHMT2 isoform A. (1311 aa) |
| | RPS27A | Ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | EXO1 | Exonuclease 1. (775 aa) |
| | AKT3-2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TDRD3 | Tudor domain-containing protein 3 isoform A. (743 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1. (515 aa) |
| | CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | PRDM1 | PR domain zinc finger protein 1. (833 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (730 aa) |
| | HIPK4 | Homeodomain-interacting protein kinase 4. (514 aa) |
| | GATAD2A | Transcriptional repressor p66-alpha isoform C. (621 aa) |
| | RBBP4-2 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (372 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | CCNA1-1 | Cyclin-A1 isoform C; Belongs to the cyclin family. (445 aa) |
| | CDK5R1L | Cyclin-dependent kinase 5 activator 1. (295 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (270 aa) |
| | RPA3 | Replication protein A subunit. (120 aa) |
| | ZNF385D-2 | U1-type domain-containing protein. (92 aa) |
| | Y1Q_0020755 | 5'-AMP-activated protein kinase subunit gamma-3-like. (99 aa) |
| | BRPF1 | Uncharacterized protein. (1677 aa) |
| | TAF6-1 | Transcription initiation factor TFIID subunit 6 isoform A. (666 aa) |
| | BRD7 | Bromodomain-containing protein 7 isoform A. (664 aa) |
| | CSNK2A2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa) |
| | BLM | Bloom syndrome protein. (1213 aa) |
| | CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) |
| | RAD1 | Cell cycle checkpoint protein RAD1. (253 aa) |
| | RICTOR | Rapamycin-insensitive companion of mTOR. (1439 aa) |
| | PRKAA1-2 | Non-specific serine/threonine protein kinase. (547 aa) |
| | SETD9-1 | SET domain-containing protein 9 isoform A. (294 aa) |
| | TAF2 | Transcription initiation factor TFIID subunit 2. (1145 aa) |
| | TP53INP1-1 | Tumor protein p53-inducible nuclear protein 1 isoform B. (225 aa) |
| | PPP1R13L | RelA-associated inhibitor. (797 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10. (121 aa) |
| | MAPKAP1 | Target of rapamycin complex 2 subunit MAPKAP1. (540 aa) |
| | RBBP4 | Histone-binding protein RBBP4. (424 aa) |
| | Y1Q_0023549 | Uncharacterized protein. (378 aa) |
| | USP7 | Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1080 aa) |
| | TXNDC11 | Thioredoxin domain-containing protein 11. (901 aa) |
| | RMI2 | RecQ-mediated genome instability protein 2. (75 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (983 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein isoform A. (516 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (242 aa) |
| | CDK3 | Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (348 aa) |
| | CHD5 | Uncharacterized protein. (1864 aa) |
| | Y1Q_0006003 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (688 aa) |
| | MTOR | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa) |
| | NOC2L | Nucleolar complex 2-like protein. (785 aa) |
| | CHD3-2 | Uncharacterized protein. (1966 aa) |
| | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1. (302 aa) |
| | RFC5 | Replication factor C subunit 5. (336 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | RFC2 | Replication factor C subunit 2. (340 aa) |
| | WRN | Werner syndrome ATP-dependent helicase. (1443 aa) |
| | PRR5 | Proline-rich protein 5 isoform B. (468 aa) |
| | Y1Q_0012818 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (341 aa) |
| | RFFL | E3 ubiquitin-protein ligase rififylin. (348 aa) |
| | Y1Q_0007802 | Transcription initiation factor TFIID subunit 4-like. (750 aa) |
| | DAXX | Death domain-associated protein 6 isoform A. (758 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (1546 aa) |
| | BARD1 | BRCA1-associated RING domain protein 1 isoform B. (792 aa) |
| | ATR | Serine/threonine-protein kinase ATR isoform A; Belongs to the PI3/PI4-kinase family. (2392 aa) |
| | Y1Q_0004744 | Protein kinase domain-containing protein. (161 aa) |
| | BANP | Protein BANP. (508 aa) |
| | ANKRD12 | Ankyrin repeat domain-containing protein 12. (761 aa) |
| | CHEK1 | Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (471 aa) |
| | CREBBP | CREB-binding protein isoform C. (2208 aa) |
| | Y1Q_0024039 | KIX domain-containing protein. (131 aa) |
| | DCLRE1B | 5' exonuclease Apollo isoform B. (1619 aa) |
| | HIPK2 | Protein kinase domain-containing protein. (1175 aa) |
| | NUAK1 | NUAK family SNF1-like kinase 1. (651 aa) |
| | RECQL4 | ATP-dependent DNA helicase Q4 isoform A. (1385 aa) |
| | POU4F1 | POU domain protein. (193 aa) |
| | TAF7L | Transcription initiation factor TFIID subunit 7-like. (353 aa) |
| | TAF9B | Transcription initiation factor TFIID subunit 9B. (255 aa) |
| | Y1Q_0006637 | PRMT5_TIM domain-containing protein. (211 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa) |
| | SUPT16H | FACT complex subunit SPT16. (1044 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator 2. (278 aa) |
| | MAPKAPK5 | MAP kinase-activated protein kinase 5 isoform B. (510 aa) |
| | SCARB1 | Scavenger receptor class B member 1 isoform A. (959 aa) |
| | RNF34 | E3 ubiquitin-protein ligase RNF34. (345 aa) |
| | RAD9B-1 | Cell cycle checkpoint control protein RAD9B isoform B. (364 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1966 aa) |
| | KXD1 | KxDL motif-containing protein 1. (293 aa) |
| | TAF5 | Transcription initiation factor TFIID subunit 5. (655 aa) |
| | AIRE | Autoimmune regulator isoform B. (519 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (705 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (159 aa) |
| | PHF20 | PHD finger protein 20. (1058 aa) |
| | MLST8 | Target of rapamycin complex subunit LST8. (403 aa) |
| | ING1 | Inhibitor of growth protein. (281 aa) |
| | CSNK2A1 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (435 aa) |
| | TAF11 | Transcription initiation factor TFIID subunit 11. (153 aa) |
| | TAF4 | Transcription initiation factor TFIID subunit 4. (976 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (450 aa) |
| | TP53RK | TP53-regulating kinase. (383 aa) |
| | L3MBTL1 | SAM domain-containing protein. (897 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1052 aa) |
| | TP53INP2 | Tumor protein p53-inducible nuclear protein 2. (152 aa) |
| | STK11 | Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (418 aa) |
| | MRE11A | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (720 aa) |
| | Y1Q_0016784 | 5'-AMP-activated protein kinase subunit gamma-3-like. (129 aa) |
| | Y1Q_0016180 | Uncharacterized protein. (89 aa) |
| | TOPBP1 | DNA topoisomerase 2-binding protein 1. (1514 aa) |
| | SMYD2 | N-lysine methyltransferase SMYD2. (382 aa) |
| | PPP1R13B | Apoptosis-stimulating of p53 protein 1. (1153 aa) |
| | FOXP4 | Fork-head domain-containing protein. (617 aa) |
| | ANKRD11 | Ankyrin repeat domain-containing protein 11. (2899 aa) |
| | PIP4K2B | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (411 aa) |
| | RHNO1 | RAD9. (261 aa) |
| | DYRK4 | Dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform B. (710 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform A. (330 aa) |
| | Y1Q_0002398 | Uncharacterized protein. (72 aa) |
| | ATM | Non-specific serine/threonine protein kinase. (3063 aa) |
| | POU4F3-2 | POU domain protein. (316 aa) |
| | PPP1R13BB | Apoptosis-stimulating of p53 protein 1 isoform D. (1133 aa) |
| | ING2 | Inhibitor of growth protein. (228 aa) |
| | POU4F2 | POU domain protein. (316 aa) |
| | ATRIP | ATR-interacting protein. (672 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein. (832 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (306 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (284 aa) |
| | Y1Q_0017424 | Uncharacterized protein. (235 aa) |
| | PIP4K2A | PIPK domain-containing protein. (405 aa) |
| | ZNF385C-1 | Zinc finger protein 385C isoform A. (1099 aa) |
| | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2. (567 aa) |
| | CCNA2 | Cyclin-A2; Belongs to the cyclin family. (382 aa) |
| | BRD1 | Uncharacterized protein. (734 aa) |
| | DYRK2 | Dual specificity tyrosine-phosphorylation-regulated kinase 2. (526 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (494 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (361 aa) |
| | PIP4K2C | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (458 aa) |
| | L3MBTL1-2 | Lethal(3)malignant brain tumor-like protein 1 isoform A. (807 aa) |
| | TAF4B | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (1010 aa) |
| | TMEM55A-1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | RBBP8-1 | DNA endonuclease RBBP8 isoform B. (936 aa) |
| | BRD9 | Bromodomain-containing protein 9 isoform B. (673 aa) |
| | Y1Q_0010122 | Uncharacterized protein. (300 aa) |
| | JMY | Junction-mediating and-regulatory protein. (834 aa) |
| | ANKRD31-1 | Putative ankyrin repeat domain-containing protein 31 isoform C. (1142 aa) |
| | SLF1 | Ankyrin repeat domain-containing protein 32. (825 aa) |
| | RAD17 | Cell cycle checkpoint protein RAD17. (696 aa) |
| | EHMT1 | Histone-lysine N-methyltransferase EHMT1. (931 aa) |
| | GATAD2B | Transcriptional repressor p66-beta isoform B. (634 aa) |
| | TAF3 | Transcription initiation factor TFIID subunit 3 isoform C. (1040 aa) |
