STRINGSTRING
RFC3 RFC3 RPA1 RPA1 RFC4 RFC4 RPS27A RPS27A RCBTB1 RCBTB1 RCBTB1-2 RCBTB1-2 REV3L REV3L RPA3 RPA3 POLI POLI MEIOB MEIOB ATAD5 ATAD5 MAD2L2 MAD2L2 RFC5 RFC5 RFC2 RFC2 SCARB1 SCARB1 KXD1 KXD1 REV1 REV1 PCNA PCNA RFC1 RFC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC3Replication factor C subunit 3. (356 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
RFC4Replication factor C subunit 4. (364 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (566 aa)
RCBTB1-2BTB domain-containing protein. (595 aa)
REV3LDNA polymerase. (1917 aa)
RPA3Replication protein A subunit. (120 aa)
POLIDNA polymerase iota isoform A. (755 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform A. (516 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1673 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (228 aa)
RFC5Replication factor C subunit 5. (336 aa)
RFC2Replication factor C subunit 2. (340 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1160 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
RFC1Replication factor C subunit 1. (1130 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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