STRINGSTRING
ERCC3 ERCC3 GTF2H5 GTF2H5 Y1Q_0024416 Y1Q_0024416 TCEANC2 TCEANC2 POLR2H POLR2H GTF2H4 GTF2H4 GPS1 GPS1 COPS2 COPS2 GTF2H1 GTF2H1 COPS7A COPS7A HMGN1 HMGN1 RPS27A RPS27A ERCC6 ERCC6 POLR2I POLR2I COPS7B COPS7B PPIE PPIE PPP1R42 PPP1R42 COPS5 COPS5 PPP1R42L PPP1R42L TCEA1 TCEA1 POLR2B POLR2B Y1Q_0020670 Y1Q_0020670 POLR2C POLR2C POLR2G POLR2G AQR AQR ERCC8 ERCC8 ERCC2 ERCC2 POLR2A POLR2A ISY1 ISY1 TCEA2 TCEA2 USP7 USP7 COPS3 COPS3 MNAT1 MNAT1 POLR2J POLR2J XPA XPA TCEA3 TCEA3 CREBBP CREBBP RBX1 RBX1 POLR2F POLR2F Y1Q_0024039 Y1Q_0024039 HMGN2 HMGN2 POLR2L-2 POLR2L-2 CUL4B CUL4B Y1Q_0015515 Y1Q_0015515 Y1Q_0005435 Y1Q_0005435 GTF2H3 GTF2H3 SCARB1 SCARB1 KXD1 KXD1 CUL4A CUL4A PRPF19 PRPF19 POLR2L-1 POLR2L-1 DDB1 DDB1 POLR2E POLR2E COPS4 COPS4 NRDE2 NRDE2 UVSSA UVSSA XAB2 XAB2 ZNF830 ZNF830 CDK7 CDK7 GTF2H2 GTF2H2 COPS6 COPS6 CCNH CCNH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (779 aa)
GTF2H5General transcription factor IIH subunit 5. (115 aa)
Y1Q_0024416Uncharacterized protein. (127 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (461 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (161 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (404 aa)
GPS1COP9 signalosome complex subunit 1 isoform A. (465 aa)
COPS2COP9 signalosome complex subunit 2 isoform B. (436 aa)
GTF2H1L-lactate dehydrogenase. (910 aa)
COPS7ACOP9 signalosome complex subunit 7a. (291 aa)
HMGN1Non-histone chromosomal protein HMG-14. (102 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
ERCC6DNA excision repair protein ERCC-6. (1491 aa)
POLR2IDNA-directed RNA polymerase II subunit RPB9; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
COPS7BCOP9 signalosome complex subunit 7b. (293 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (300 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (171 aa)
COPS5COP9 signalosome complex subunit 5. (149 aa)
PPP1R42LProtein phosphatase 1 regulatory subunit 42. (308 aa)
TCEA1Transcription elongation factor A protein 1. (304 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
Y1Q_0020670COP9 signalosome complex subunit 4-like. (104 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (275 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (137 aa)
AQRIntron-binding protein aquarius isoform A. (1428 aa)
ERCC8DNA excision repair protein ERCC-8. (399 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (795 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1897 aa)
ISY1Pre-mRNA-splicing factor ISY1-like protein. (281 aa)
TCEA2Transcription elongation factor A protein 2. (300 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1080 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
XPADNA repair protein complementing XP-A cells. (244 aa)
TCEA3Transcription elongation factor A protein 3. (457 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (104 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
HMGN2Non-histone chromosomal protein HMG-17. (72 aa)
POLR2L-2DNA-directed RNA polymerases I, II, and III subunit RPABC5. (74 aa)
CUL4BCullin-4B; Belongs to the cullin family. (614 aa)
Y1Q_0015515Cullin domain-containing protein; Belongs to the cullin family. (160 aa)
Y1Q_0005435Pre-mRNA-splicing factor SYF1-like. (113 aa)
GTF2H3General transcription factor IIH subunit 3. (328 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
CUL4ACULLIN_2 domain-containing protein; Belongs to the cullin family. (763 aa)
PRPF19Pre-mRNA-processing factor 19. (492 aa)
POLR2L-1DNA-directed RNA polymerases I, II, and III subunit RPABC5. (104 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (231 aa)
COPS4COP9 signalosome complex subunit 4. (190 aa)
NRDE2NRDE2-like protein. (1173 aa)
UVSSAUV-stimulated scaffold protein A. (761 aa)
XAB2Pre-mRNA-splicing factor SYF1. (747 aa)
ZNF830Zinc finger protein 830. (327 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
COPS6COP9 signalosome complex subunit 6. (297 aa)
CCNHCyclin-H; Belongs to the cyclin family. (247 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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