STRINGSTRING
ERCC6 ERCC6 POLR2I POLR2I POLR2L-2 POLR2L-2 PPIE PPIE SPOCD1 SPOCD1 TCEA1 TCEA1 RFC3 RFC3 POLR2B POLR2B RPA3 RPA3 POLR2C POLR2C POLR2G POLR2G POLD4 POLD4 Y1Q_0011106 Y1Q_0011106 POLD3-1 POLD3-1 CCNH CCNH GTF2H2 GTF2H2 CDK7 CDK7 POLK POLK ZNF830 ZNF830 LIG1 LIG1 XAB2 XAB2 POLE2 POLE2 PHF3 PHF3 RFC1 RFC1 UVSSA UVSSA NRDE2 NRDE2 PCNA PCNA Y1Q_0007595 Y1Q_0007595 POLR2E POLR2E Y1Q_0006787 Y1Q_0006787 DDB1 DDB1 POLR2L-1 POLR2L-1 PRPF19 PRPF19 POLD2 POLD2 CUL4A CUL4A KXD1 KXD1 SCARB1 SCARB1 GTF2H3 GTF2H3 Y1Q_0005435 Y1Q_0005435 Y1Q_0015515 Y1Q_0015515 XRCC1 XRCC1 AQR AQR ERCC8 ERCC8 ERCC2 ERCC2 POLR2A POLR2A CUL4B CUL4B ISY1 ISY1 TCEA2 TCEA2 USP7 USP7 MEIOB MEIOB ATAD5 ATAD5 MNAT1 MNAT1 RFC5 RFC5 POLR2J POLR2J RFC2 RFC2 LIG3 LIG3 USP40 USP40 Y1Q_0008724 Y1Q_0008724 TCEA3 TCEA3 CREBBP CREBBP RBX1 RBX1 POLR2F POLR2F Y1Q_0024039 Y1Q_0024039 Y1Q_0000842 Y1Q_0000842 POLE POLE HMGN2 HMGN2 RPA1 RPA1 POLD1-2 POLD1-2 ERCC3 ERCC3 GTF2H5 GTF2H5 TCEANC2 TCEANC2 POLR2H POLR2H GTF2H4 GTF2H4 RFC4 RFC4 GTF2H1 GTF2H1 HMGN1 HMGN1 POLE3 POLE3 RPS27A RPS27A RCBTB1 RCBTB1 RCBTB1-2 RCBTB1-2 POLD1 POLD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERCC6DNA excision repair protein ERCC-6. (1491 aa)
POLR2IDNA-directed RNA polymerase II subunit RPB9; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
POLR2L-2DNA-directed RNA polymerases I, II, and III subunit RPABC5. (74 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (300 aa)
SPOCD1SPOC domain-containing protein 1 isoform A. (1200 aa)
TCEA1Transcription elongation factor A protein 1. (304 aa)
RFC3Replication factor C subunit 3. (356 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
RPA3Replication protein A subunit. (120 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (275 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (137 aa)
POLD4DNA polymerase delta subunit 4 isoform A. (206 aa)
Y1Q_0011106Short transient receptor potential channel 2-like. (506 aa)
POLD3-1DNA polymerase delta subunit 3 isoform A. (466 aa)
CCNHCyclin-H; Belongs to the cyclin family. (247 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
POLKDNA polymerase kappa isoform A. (651 aa)
ZNF830Zinc finger protein 830. (327 aa)
LIG1DNA ligase. (954 aa)
XAB2Pre-mRNA-splicing factor SYF1. (747 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
PHF3PHD finger protein 3. (884 aa)
RFC1Replication factor C subunit 1. (1130 aa)
UVSSAUV-stimulated scaffold protein A. (761 aa)
NRDE2NRDE2-like protein. (1173 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
Y1Q_0007595DNA_pol_B_exo1 domain-containing protein. (86 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (231 aa)
Y1Q_0006787DNA polymerase delta catalytic subunit-like. (198 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
POLR2L-1DNA-directed RNA polymerases I, II, and III subunit RPABC5. (104 aa)
PRPF19Pre-mRNA-processing factor 19. (492 aa)
POLD2DNA polymerase delta subunit 2. (501 aa)
CUL4ACULLIN_2 domain-containing protein; Belongs to the cullin family. (763 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
GTF2H3General transcription factor IIH subunit 3. (328 aa)
Y1Q_0005435Pre-mRNA-splicing factor SYF1-like. (113 aa)
Y1Q_0015515Cullin domain-containing protein; Belongs to the cullin family. (160 aa)
XRCC1DNA repair protein XRCC1-like. (608 aa)
AQRIntron-binding protein aquarius isoform A. (1428 aa)
ERCC8DNA excision repair protein ERCC-8. (399 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (795 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1897 aa)
CUL4BCullin-4B; Belongs to the cullin family. (614 aa)
ISY1Pre-mRNA-splicing factor ISY1-like protein. (281 aa)
TCEA2Transcription elongation factor A protein 2. (300 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1080 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform A. (516 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1673 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
RFC5Replication factor C subunit 5. (336 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
RFC2Replication factor C subunit 2. (340 aa)
LIG3DNA ligase. (906 aa)
USP40Ubiquitin carboxyl-terminal hydrolase 40; Belongs to the peptidase C19 family. (1246 aa)
Y1Q_0008724Uncharacterized protein. (128 aa)
TCEA3Transcription elongation factor A protein 3. (457 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (104 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
Y1Q_0000842DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (917 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1114 aa)
HMGN2Non-histone chromosomal protein HMG-17. (72 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
POLD1-2DNA polymerase delta catalytic subunit. (392 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (779 aa)
GTF2H5General transcription factor IIH subunit 5. (115 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (461 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (161 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (404 aa)
RFC4Replication factor C subunit 4. (364 aa)
GTF2H1L-lactate dehydrogenase. (910 aa)
HMGN1Non-histone chromosomal protein HMG-14. (102 aa)
POLE3DNA polymerase epsilon subunit 3. (143 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (566 aa)
RCBTB1-2BTB domain-containing protein. (595 aa)
POLD1DNA polymerase. (439 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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