STRINGSTRING
ATM ATM EHMT1 EHMT1 JMY JMY L3MBTL1-2 L3MBTL1-2 MDM2 MDM2 SMYD2 SMYD2 L3MBTL1 L3MBTL1 KXD1 KXD1 Y1Q_0006637 Y1Q_0006637 Y1Q_0024039 Y1Q_0024039 CREBBP CREBBP PRMT5 PRMT5 L3MBTL1-1 L3MBTL1-1 TTC5 TTC5 MDM4 MDM4 EHMT2 EHMT2 RPS27A RPS27A TP53 TP53 SETD9-1 SETD9-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATMNon-specific serine/threonine protein kinase. (3063 aa)
EHMT1Histone-lysine N-methyltransferase EHMT1. (931 aa)
JMYJunction-mediating and-regulatory protein. (834 aa)
L3MBTL1-2Lethal(3)malignant brain tumor-like protein 1 isoform A. (807 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (494 aa)
SMYD2N-lysine methyltransferase SMYD2. (382 aa)
L3MBTL1SAM domain-containing protein. (897 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
Y1Q_0006637PRMT5_TIM domain-containing protein. (211 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
PRMT5Protein arginine N-methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (242 aa)
L3MBTL1-1Lethal(3)malignant brain tumor-like protein 1. (844 aa)
TTC5Tetratricopeptide repeat protein 5. (439 aa)
MDM4Protein Mdm4. (513 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2 isoform A. (1311 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
SETD9-1SET domain-containing protein 9 isoform A. (294 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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