59 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	STAM	Signal transducing adapter molecule 1 isoform C. (582 aa)
	TNS1	Tensin-1 isoform B. (709 aa)
	SOS1-2	Son of sevenless-like protein. (1379 aa)
	RAB4A	Ras-related protein Rab-4A. (218 aa)
	LAMB2	Uncharacterized protein. (1523 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Y1Q_0010680	Uncharacterized protein. (176 aa)
	GAB1	GRB2-associated-binding protein 1 isoform A. (720 aa)
	MEGF11	Uncharacterized protein. (1144 aa)
	SH3GL3	Endophilin-A3. (353 aa)
	USP8	Ubiquitin carboxyl-terminal hydrolase 8 isoform A; Belongs to the peptidase C19 family. (1133 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta isoform A. (1187 aa)
	Y1Q_0005628	Fibrillar collagen NC1 domain-containing protein. (1950 aa)
	LAMC3-2	Uncharacterized protein. (1535 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1071 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1011 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	FNDC3A-2	Uncharacterized protein. (1195 aa)
	LAMC1	Laminin subunit gamma-1. (1184 aa)
	LAMC3	Laminin subunit gamma-3. (1574 aa)
	LAMA4	Laminin subunit alpha-4. (1825 aa)
	LRIG1	Uncharacterized protein. (1031 aa)
	CRK	Adapter molecule crk. (291 aa)
	HPN	Serine protease hepsin; Belongs to the peptidase S1 family. (424 aa)
	Y1Q_0018542	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (627 aa)
	RANBP10	Ran-binding protein 10 isoform A. (641 aa)
	STAM-2	Uncharacterized protein. (335 aa)
	Y1Q_0019087	Uncharacterized protein. (152 aa)
	SPINT1	Kunitz-type protease inhibitor 1. (473 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate isoform B. (853 aa)
	SH3GL1	Uncharacterized protein. (367 aa)
	SH3KBP1	SH3 domain-containing kinase-binding protein 1 isoform A. (661 aa)
	ARF6	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	GGA1L	ADP-ribosylation factor-binding protein GGA1. (752 aa)
	Y1Q_0006103	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (429 aa)
	KRAS-2	GTPase KRas. (219 aa)
	COL24A1	Collagen alpha-1(XXIV) chain. (1311 aa)
	RANBP10-2	Uncharacterized protein. (608 aa)
	KRAS-1	GTPase KRas. (215 aa)
	Y1Q_0015649	Uncharacterized protein. (1191 aa)
	LAMB1-2	Uncharacterized protein. (1788 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (723 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	Y1Q_0006325	Uncharacterized protein. (188 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	SH3GL2	Endophilin-A1 isoform A. (352 aa)
	ITGA3-2	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1085 aa)
	STAT4	Signal transducer and activator of transcription. (849 aa)
	TNS4	Tensin-4 isoform A. (764 aa)
	RAB4B	Ras-related protein Rab-4B. (210 aa)
	SPINT2	Kunitz-type protease inhibitor 2. (92 aa)
	MET-2	Uncharacterized protein. (1348 aa)
	RAP1B	Ras-related protein Rap-1b. (245 aa)
	TNS3	Tensin-3 isoform E. (1563 aa)
	NRAS	GTPase NRas. (189 aa)
	CD2AP	CD2-associated protein isoform C. (658 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	CRK	A0A151N3F8	A0A151MLC9	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Adapter molecule crk.	0.686
ARF6	GAB1	A0A151N3F8	A0A151M7H7	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	GRB2-associated-binding protein 1 isoform A.	0.622
ARF6	GGA1L	A0A151N3F8	A0A151N3I7	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-binding protein GGA1.	0.925
ARF6	GRB2	A0A151N3F8	A0A151N2T8	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Growth factor receptor-bound protein 2.	0.652
ARF6	HGF	A0A151N3F8	A0A151NPX2	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.606
ARF6	MET-2	A0A151N3F8	A0A151PES3	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.743
ARF6	RAB4A	A0A151N3F8	A0A151M2Q2	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein Rab-4A.	0.512
ARF6	RAB4B	A0A151N3F8	A0A151PE10	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein Rab-4B.	0.512
CD2AP	GRB2	A0A151PJ31	A0A151N2T8	CD2-associated protein isoform C.	Growth factor receptor-bound protein 2.	0.692
CD2AP	HGF	A0A151PJ31	A0A151NPX2	CD2-associated protein isoform C.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.440
CD2AP	HGS	A0A151PJ31	A0A151MW83	CD2-associated protein isoform C.	Hepatocyte growth factor-regulated tyrosine kinase substrate isoform B.	0.608
CD2AP	KXD1	A0A151PJ31	A0A151NUA6	CD2-associated protein isoform C.	KxDL motif-containing protein 1.	0.790
CD2AP	MET-2	A0A151PJ31	A0A151PES3	CD2-associated protein isoform C.	Uncharacterized protein.	0.724
CD2AP	RPS27A	A0A151PJ31	A0A151MGG2	CD2-associated protein isoform C.	Ubiquitin-40S ribosomal protein S27a.	0.821
CD2AP	SH3GL1	A0A151PJ31	A0A151MZY7	CD2-associated protein isoform C.	Uncharacterized protein.	0.570
CD2AP	SH3GL2	A0A151PJ31	A0A151P1N8	CD2-associated protein isoform C.	Endophilin-A1 isoform A.	0.570
CD2AP	SH3GL3	A0A151PJ31	A0A151M9D3	CD2-associated protein isoform C.	Endophilin-A3.	0.570
CD2AP	SOS1-2	A0A151PJ31	A0A151M1Q1	CD2-associated protein isoform C.	Son of sevenless-like protein.	0.646
CD2AP	STAM	A0A151PJ31	A0A151M0F9	CD2-associated protein isoform C.	Signal transducing adapter molecule 1 isoform C.	0.541
CD2AP	STAM-2	A0A151PJ31	A0A151MPX3	CD2-associated protein isoform C.	Uncharacterized protein.	0.443