19 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SH3GL2	Endophilin-A1 isoform A. (352 aa)
	STAM	Signal transducing adapter molecule 1 isoform C. (582 aa)
	SH3GL3	Endophilin-A3. (353 aa)
	USP8	Ubiquitin carboxyl-terminal hydrolase 8 isoform A; Belongs to the peptidase C19 family. (1133 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta isoform A. (1187 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	LRIG1	Uncharacterized protein. (1031 aa)
	STAM-2	Uncharacterized protein. (335 aa)
	Y1Q_0019087	Uncharacterized protein. (152 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate isoform B. (853 aa)
	SH3GL1	Uncharacterized protein. (367 aa)
	SH3KBP1	SH3 domain-containing kinase-binding protein 1 isoform A. (661 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (429 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (723 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	MET-2	Uncharacterized protein. (1348 aa)
	CD2AP	CD2-associated protein isoform C. (658 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD2AP	GRB2	A0A151PJ31	A0A151N2T8	CD2-associated protein isoform C.	Growth factor receptor-bound protein 2.	0.692
CD2AP	HGF	A0A151PJ31	A0A151NPX2	CD2-associated protein isoform C.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.440
CD2AP	HGS	A0A151PJ31	A0A151MW83	CD2-associated protein isoform C.	Hepatocyte growth factor-regulated tyrosine kinase substrate isoform B.	0.608
CD2AP	KXD1	A0A151PJ31	A0A151NUA6	CD2-associated protein isoform C.	KxDL motif-containing protein 1.	0.790
CD2AP	MET-2	A0A151PJ31	A0A151PES3	CD2-associated protein isoform C.	Uncharacterized protein.	0.724
CD2AP	RPS27A	A0A151PJ31	A0A151MGG2	CD2-associated protein isoform C.	Ubiquitin-40S ribosomal protein S27a.	0.821
CD2AP	SH3GL1	A0A151PJ31	A0A151MZY7	CD2-associated protein isoform C.	Uncharacterized protein.	0.570
CD2AP	SH3GL2	A0A151PJ31	A0A151P1N8	CD2-associated protein isoform C.	Endophilin-A1 isoform A.	0.570
CD2AP	SH3GL3	A0A151PJ31	A0A151M9D3	CD2-associated protein isoform C.	Endophilin-A3.	0.570
CD2AP	STAM	A0A151PJ31	A0A151M0F9	CD2-associated protein isoform C.	Signal transducing adapter molecule 1 isoform C.	0.541
CD2AP	STAM-2	A0A151PJ31	A0A151MPX3	CD2-associated protein isoform C.	Uncharacterized protein.	0.443
CD2AP	Y1Q_0019087	A0A151PJ31	A0A151MPX8	CD2-associated protein isoform C.	Uncharacterized protein.	0.443
GRB2	CD2AP	A0A151N2T8	A0A151PJ31	Growth factor receptor-bound protein 2.	CD2-associated protein isoform C.	0.692
GRB2	HGF	A0A151N2T8	A0A151NPX2	Growth factor receptor-bound protein 2.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.631
GRB2	HGS	A0A151N2T8	A0A151MW83	Growth factor receptor-bound protein 2.	Hepatocyte growth factor-regulated tyrosine kinase substrate isoform B.	0.633
GRB2	KXD1	A0A151N2T8	A0A151NUA6	Growth factor receptor-bound protein 2.	KxDL motif-containing protein 1.	0.641
GRB2	LRIG1	A0A151N2T8	A0A151MKF4	Growth factor receptor-bound protein 2.	Uncharacterized protein.	0.588
GRB2	MET-2	A0A151N2T8	A0A151PES3	Growth factor receptor-bound protein 2.	Uncharacterized protein.	0.977
GRB2	PTPN1	A0A151N2T8	A0A151NYZ9	Growth factor receptor-bound protein 2.	Tyrosine-protein phosphatase non-receptor type.	0.600
GRB2	PTPN2	A0A151N2T8	A0A151NF96	Growth factor receptor-bound protein 2.	Tyrosine-protein phosphatase non-receptor type.	0.478