STRINGSTRING
ING2 ING2 TMEM55A-1 TMEM55A-1 PIP4K2C PIP4K2C PIP4K2A PIP4K2A PIP4K2B PIP4K2B FOXP4 FOXP4 ING1 ING1 PIN1 PIN1 Y1Q_0024039 Y1Q_0024039 CREBBP CREBBP TP53 TP53 TMEM55B TMEM55B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ING2Inhibitor of growth protein. (228 aa)
TMEM55A-1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (458 aa)
PIP4K2APIPK domain-containing protein. (405 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (411 aa)
FOXP4Fork-head domain-containing protein. (617 aa)
ING1Inhibitor of growth protein. (281 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (159 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
TMEM55BPhosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (208 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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