STRINGSTRING
PSMD1 PSMD1 HYKK HYKK PSMC3 PSMC3 CCND1 CCND1 PSMA1 PSMA1 CDKN1C CDKN1C PSMD5-1 PSMD5-1 PSMB7 PSMB7 RPS27A RPS27A AKT3-2 AKT3-2 ITM2B ITM2B CDK2 CDK2 PSMD6 PSMD6 PSMB8 PSMB8 PSMB9 PSMB9 CCNA1-1 CCNA1-1 AKT2 AKT2 SKP2 SKP2 CCNE2-1 CCNE2-1 Y1Q_0005128 Y1Q_0005128 PSMD12 PSMD12 CDK3 CDK3 MNAT1 MNAT1 Y1Q_0019034 Y1Q_0019034 CCNE1 CCNE1 CDKN1A CDKN1A Y1Q_0008616 Y1Q_0008616 PSMA5 PSMA5 PSMC5 PSMC5 PSMC4 PSMC4 WEE2-1 WEE2-1 PSMA6 PSMA6 PSME2 PSME2 PSME1 PSME1 PSMD10 PSMD10 CKS1B CKS1B PSMD7 PSMD7 PSMC2 PSMC2 PSMB5 PSMB5 PSMD9-1 PSMD9-1 SCARB1 SCARB1 PSMB6 PSMB6 KXD1 KXD1 PSMD13 PSMD13 RBBP8NL RBBP8NL PSMF1 PSMF1 CUL1 CUL1 PSMD3 PSMD3 PSMB3 PSMB3 CDKN1B CDKN1B CDKN1D CDKN1D PSMD2 PSMD2 PSMC1 PSMC1 PSMD11 PSMD11 Y1Q_0017424 Y1Q_0017424 PSMC6 PSMC6 CCNA2 CCNA2 PSMB2 PSMB2 CABLES1 CABLES1 CDK7 CDK7 CCNH CCNH PSMD8 PSMD8 PSMD14 PSMD14 PSMA3 PSMA3 AKT3 AKT3 PSMB1 PSMB1 PSMB4 PSMB4 PSMD4 PSMD4 CKS2 CKS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
HYKKProteasome endopeptidase complex. (600 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (223 aa)
PSMD5-126S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
PSMB7Proteasome subunit beta. (274 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
AKT3-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ITM2BIntegral membrane protein 2B isoform B. (1151 aa)
CDK2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (348 aa)
PSMB8Proteasome subunit beta. (282 aa)
PSMB9Proteasome subunit beta. (216 aa)
CCNA1-1Cyclin-A1 isoform C; Belongs to the cyclin family. (445 aa)
AKT2Non-specific serine/threonine protein kinase. (270 aa)
SKP2S-phase kinase-associated protein 2. (419 aa)
CCNE2-1G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (410 aa)
Y1Q_0005128Proteasome subunit beta. (277 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (441 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (348 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
Y1Q_0019034RPN1_C domain-containing protein. (356 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (232 aa)
Y1Q_0008616HSA domain-containing protein. (1301 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
WEE2-1Wee1-like protein kinase. (592 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
PSME1Proteasome activator complex subunit 1. (150 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB5Proteasome subunit beta type-5. (211 aa)
PSMD9-126S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
PSMB6Proteasome subunit beta. (227 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
RBBP8NLRBBP8 N-terminal-like protein. (691 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (521 aa)
PSMB3Proteasome subunit beta. (205 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (131 aa)
CDKN1DCyclin-dependent kinase inhibitor 1D. (153 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2. (513 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (518 aa)
Y1Q_0017424Uncharacterized protein. (235 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (382 aa)
PSMB2Proteasome subunit beta. (201 aa)
CABLES1CDK5 and ABL1 enzyme substrate 1. (397 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
CCNHCyclin-H; Belongs to the cyclin family. (247 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (257 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (460 aa)
PSMA3Proteasome subunit alpha type. (256 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PSMB1Proteasome subunit beta. (240 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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