STRINGSTRING
PPP4R4 PPP4R4 E2F5 E2F5 CCNH CCNH CDKN2C CDKN2C CDK4 CDK4 Y1Q_0010680 Y1Q_0010680 PPP2CA PPP2CA CKS2 CKS2 PRR5L PRR5L CCND1 CCND1 CDKN1C CDKN1C PPP2R1A PPP2R1A FNDC3A FNDC3A RPS27A RPS27A RBL1 RBL1 FNDC3A-2 FNDC3A-2 ITM2B ITM2B CDK2 CDK2 FNBP4 FNBP4 LYN LYN CDK6 CDK6 RBL2 RBL2 SKP2 SKP2 CCNE2-1 CCNE2-1 CDK3 CDK3 MNAT1 MNAT1 PPP2CB PPP2CB CCNE1 CCNE1 CDKN1A CDKN1A TFDP2 TFDP2 CCND3 CCND3 PPP4R1-2 PPP4R1-2 E2F2-1 E2F2-1 Y1Q_0008090 Y1Q_0008090 PPP2R3B PPP2R3B PPP2R3C PPP2R3C Y1Q_0015649 Y1Q_0015649 CKS1B CKS1B SCARB1 SCARB1 CDKN2D CDKN2D KXD1 KXD1 PPP2R3B-2 PPP2R3B-2 CDK7 CDK7 PPP4R1 PPP4R1 CUL1 CUL1 E2F1 E2F1 CCND2 CCND2 CDKN1B CDKN1B CDKN1D CDKN1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform A. (864 aa)
E2F5Transcription factor E2F5. (386 aa)
CCNHCyclin-H; Belongs to the cyclin family. (247 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (170 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Y1Q_0010680Uncharacterized protein. (176 aa)
PPP2CASerine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
PRR5LProline-rich protein 5-like. (349 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (223 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1011 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
RBL1Retinoblastoma-like protein 1 isoform A. (1076 aa)
FNDC3A-2Uncharacterized protein. (1195 aa)
ITM2BIntegral membrane protein 2B isoform B. (1151 aa)
CDK2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
FNBP4Formin-binding protein 4 isoform B. (904 aa)
LYNTyrosine-protein kinase. (562 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RBL2Uncharacterized protein. (1056 aa)
SKP2S-phase kinase-associated protein 2. (419 aa)
CCNE2-1G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (410 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (348 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (232 aa)
TFDP2Transcription factor. (447 aa)
CCND3G1/S-specific cyclin-D3; Belongs to the cyclin family. (293 aa)
PPP4R1-2WRNPLPNID domain-containing protein. (952 aa)
E2F2-1Transcription factor E2F2 isoform A. (382 aa)
Y1Q_0008090LisH domain-containing protein. (1143 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (1138 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (450 aa)
Y1Q_0015649Uncharacterized protein. (1191 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (167 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
PPP2R3B-2Uncharacterized protein. (569 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (956 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
E2F1Transcription factor E2F1. (426 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (291 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (131 aa)
CDKN1DCyclin-dependent kinase inhibitor 1D. (153 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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