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| | ANAPC7 | Anaphase-promoting complex subunit 7. (608 aa) |
| | PSMD5-1 | 26S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa) |
| | CDC26 | Anaphase-promoting complex subunit CDC26. (84 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (675 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (143 aa) |
| | Y1Q_0003135 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (127 aa) |
| | PSMA1 | Proteasome subunit alpha type. (261 aa) |
| | PSMC3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa) |
| | HYKK | Proteasome endopeptidase complex. (600 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa) |
| | CDC7-1 | Cell division cycle 7-related protein kinase isoform B. (672 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (949 aa) |
| | MCM9L | DNA helicase MCM9. (752 aa) |
| | MCM9 | DNA helicase MCM9; Belongs to the MCM family. (463 aa) |
| | KPNA5 | Importin subunit alpha; Belongs to the importin alpha family. (539 aa) |
| | PSMB1 | Proteasome subunit beta. (240 aa) |
| | PSMA3 | Proteasome subunit alpha type. (256 aa) |
| | KPNA1 | Importin subunit alpha; Belongs to the importin alpha family. (515 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1. (1942 aa) |
| | GINS1 | DNA replication complex GINS protein PSF1. (195 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (822 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (460 aa) |
| | HIST1H2BF | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | HIST2H2BE | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | Y1Q_0020100 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | Y1Q_0020098 | Histone H2B; Belongs to the histone H2B family. (166 aa) |
| | Y1Q_0022362 | Histone H2B.3-like. (135 aa) |
| | 44G24.1 | Histone H2B.3; Belongs to the histone H2B family. (142 aa) |
| | POLD1-2 | DNA polymerase delta catalytic subunit. (392 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa) |
| | PSMB7 | Proteasome subunit beta. (274 aa) |
| | Y1Q_0019041 | XPGI domain-containing protein. (343 aa) |
| | UBE2S | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (215 aa) |
| | PSME4 | Proteasome activator complex subunit 4. (1808 aa) |
| | RPS27A | Ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | MCM8 | DNA helicase MCM8; Belongs to the MCM family. (795 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1. (566 aa) |
| | RCBTB1-2 | BTB domain-containing protein. (595 aa) |
| | CDC23 | Cell division cycle 23-like protein isoform B. (585 aa) |
| | CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19. (205 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (888 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6. (348 aa) |
| | PSMB8 | Proteasome subunit beta. (282 aa) |
| | PSMB9 | Proteasome subunit beta. (216 aa) |
| | KPNA6 | Importin subunit alpha; Belongs to the importin alpha family. (551 aa) |
| | Y1Q_0003907 | MCM domain-containing protein. (120 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (581 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | CCNA1-1 | Cyclin-A1 isoform C; Belongs to the cyclin family. (445 aa) |
| | RPA3 | Replication protein A subunit. (120 aa) |
| | ORC6 | Origin recognition complex subunit 6. (267 aa) |
| | GINS3 | DNA replication complex GINS protein PSF3. (214 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (597 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform A. (713 aa) |
| | POLD4 | DNA polymerase delta subunit 4 isoform A. (206 aa) |
| | CDT1 | DNA replication factor Cdt1. (516 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (226 aa) |
| | SKP2 | S-phase kinase-associated protein 2. (419 aa) |
| | CCNE2-1 | G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (410 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (179 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa) |
| | Y1Q_0005128 | Proteasome subunit beta. (277 aa) |
| | POLA1 | DNA polymerase. (1498 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein isoform A. (516 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (441 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5. (1673 aa) |
| | CDK3 | Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (348 aa) |
| | RFC5 | Replication factor C subunit 5. (336 aa) |
| | RFC2 | Replication factor C subunit 2. (340 aa) |
| | Y1Q_0019034 | RPN1_C domain-containing protein. (356 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa) |
| | Y1Q_0009388 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) |
| | Y1Q_0008616 | HSA domain-containing protein. (1301 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PSMC5 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa) |
| | Y1Q_0008724 | Uncharacterized protein. (128 aa) |
| | ORC2 | Origin recognition complex subunit 2. (569 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (772 aa) |
| | GMNN | Geminin. (223 aa) |
| | FZR1 | Fizzy-related protein-like protein. (493 aa) |
| | PSMC4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (104 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (773 aa) |
| | Y1Q_0016099 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | Y1Q_0000842 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (917 aa) |
| | Y1Q_0000841 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (311 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1114 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | PSME2 | Proteasome activator complex subunit 2. (242 aa) |
| | PSME1 | Proteasome activator complex subunit 1. (150 aa) |
| | H2AFZ | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10. (226 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | HIST1H2B5L | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (322 aa) |
| | H2AFV | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | ORC5 | Origin recognition complex subunit 5. (420 aa) |
| | MCM10 | MCM10-like protein. (868 aa) |
| | PSMC2 | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | PSMB11 | Proteasome subunit beta. (261 aa) |
| | PSMB5 | Proteasome subunit beta type-5. (211 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11. (98 aa) |
| | PSMD9-1 | 26S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5. (756 aa) |
| | SCARB1 | Scavenger receptor class B member 1 isoform A. (959 aa) |
| | CDC45 | Cell division control 45-like protein. (501 aa) |
| | HIST1H4D | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | Y1Q_0006757 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa) |
| | PSMB6 | Proteasome subunit beta. (227 aa) |
| | KXD1 | KxDL motif-containing protein 1. (293 aa) |
| | CDC16 | Cell division cycle 16-like protein. (622 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (501 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | ANAPC16 | Anaphase-promoting complex subunit 16. (110 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1052 aa) |
| | Y1Q_0006787 | DNA polymerase delta catalytic subunit-like. (198 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit. (273 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (776 aa) |
| | Y1Q_0007595 | DNA_pol_B_exo1 domain-containing protein. (86 aa) |
| | GLTSCR1-1 | Glioma tumor suppressor candidate region 1 protein isoform C. (1814 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (521 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa) |
| | Y1Q_0014681 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (119 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2. (513 aa) |
| | PSMC1 | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa) |
| | RFC1 | Replication factor C subunit 1. (1130 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (796 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (456 aa) |
| | CDC27 | Cell division cycle 27-like protein. (834 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (518 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (549 aa) |
| | Y1Q_0018383 | Histone H2B-like; Belongs to the histone H2B family. (152 aa) |
| | Y1Q_0014479 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (503 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa) |
| | PSMC6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) |
| | Y1Q_0012805 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | CCNA2 | Cyclin-A2; Belongs to the cyclin family. (382 aa) |
| | UBE2C | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | LIG1 | DNA ligase. (954 aa) |
| | POLD3-1 | DNA polymerase delta subunit 3 isoform A. (466 aa) |
| | POLD1 | DNA polymerase. (439 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (257 aa) |
| | ANAPC15 | Anaphase-promoting complex subunit 15. (94 aa) |
