STRINGSTRING
CENPO CENPO SPC25 SPC25 DYNC1I2 DYNC1I2 CLASP1 CLASP1 NUP98 NUP98 ANAPC1 ANAPC1 BUB1 BUB1 PPP2R5E PPP2R5E NUP133 NUP133 PPP2CA PPP2CA ERCC6L2 ERCC6L2 ZWILCH ZWILCH CKAP5-2 CKAP5-2 KIF18A KIF18A PPP2R1A PPP2R1A PPP2R5D PPP2R5D ANAPC2 ANAPC2 CDC26 CDC26 UBE2S UBE2S XPO1 XPO1 AHCTF1 AHCTF1 CDC23 CDC23 MAPRE1 MAPRE1 CENPL CENPL NUF2 NUF2 Y1Q_0002109 Y1Q_0002109 CENPC CENPC NDEL1 NDEL1 DSN1 DSN1 PLK1 PLK1 CDC16 CDC16 RANBP2 RANBP2 INCENP INCENP NNF1 NNF1 INCENPL INCENPL ANAPC16 ANAPC16 ZW10 ZW10 RCC2 RCC2 CLASP2 CLASP2 NSL1 NSL1 PPP2R5C PPP2R5C GLTSCR1-1 GLTSCR1-1 BUB3 BUB3 CENPF CENPF CDC20 CDC20 ERCC6L ERCC6L DYNC1H1 DYNC1H1 PPP2R5C-2 PPP2R5C-2 ANAPC4 ANAPC4 CENPP CENPP CENPPL CENPPL KIF2C KIF2C CDC27 CDC27 MAD2L1 MAD2L1 NUP107 NUP107 UBE2C UBE2C CENPH CENPH ANAPC15 ANAPC15 ITGB3BP ITGB3BP SPC24 SPC24 NUP43 NUP43 CENPN CENPN CENPI CENPI ZWINT ZWINT SPDL1 SPDL1 ANAPC11 ANAPC11 ANAPC7 ANAPC7 ANAPC5 ANAPC5 CLIP1 CLIP1 KNTC1 KNTC1 NUDC-1 NUDC-1 RANGAP1 RANGAP1 NUP37 NUP37 CENPM CENPM CDCA8 CDCA8 SEH1L SEH1L NDC80 NDC80 BIRC5 BIRC5 CENPQ-1 CENPQ-1 BIRC5B BIRC5B SGOL2 SGOL2 Y1Q_0008603 Y1Q_0008603 DYNC1LI2 DYNC1LI2 CLIP2 CLIP2 MIS12 MIS12 DYNLL2 DYNLL2 PAFAH1B1 PAFAH1B1 PPP2CB PPP2CB DYNLL1 DYNLL1 NUP85 NUP85 MAD1L1 MAD1L1 NDE1 NDE1 ANAPC10 ANAPC10 CDC20B-1 CDC20B-1 Y1Q_0009945 Y1Q_0009945 CENPK CENPK SKA1-1 SKA1-1 BUB1B BUB1B CASC5 CASC5 PPP2R5B PPP2R5B MTUS2-1 MTUS2-1 MAPRE3-1 MAPRE3-1 DYNC1LI1 DYNC1LI1 SGOL1 SGOL1 DYNC1I1 DYNC1I1 MAPRE2 MAPRE2 NUP160 NUP160 CKAP5 CKAP5 SEC13 SEC13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CENPOCentromere protein O. (351 aa)
SPC25Kinetochore protein Spc25. (269 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2 isoform C. (726 aa)
CLASP1CLIP-associating protein 1 isoform B. (1464 aa)
NUP98Nuclear pore complex protein Nup98-Nup96 isoform A. (1816 aa)
ANAPC1Anaphase-promoting complex subunit 1. (1942 aa)
BUB1Mitotic checkpoint serine/threonine-protein kinase BUB1. (1069 aa)
PPP2R5ESerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (515 aa)
NUP133Nuclear pore complex protein Nup133. (1154 aa)
PPP2CASerine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa)
ERCC6L2DNA excision repair protein ERCC-6-like 2. (1396 aa)
ZWILCHZwilch-like protein. (568 aa)
CKAP5-2Uncharacterized protein. (2029 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa)
PPP2R5DSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (596 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (675 aa)
CDC26Anaphase-promoting complex subunit CDC26. (84 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (215 aa)
XPO1Exportin-1. (1001 aa)
AHCTF1Protein ELYS. (1901 aa)
CDC23Cell division cycle 23-like protein isoform B. (585 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (286 aa)
CENPLCentromere protein L isoform A. (341 aa)
NUF2Kinetochore protein Nuf2. (553 aa)
Y1Q_0002109Uncharacterized protein. (179 aa)
CENPCCentromere protein C. (613 aa)
NDEL1Nuclear distribution protein nudE-like 1. (369 aa)
DSN1Kinetochore-associated DSN1-like protein. (350 aa)
PLK1Serine/threonine-protein kinase PLK. (664 aa)
CDC16Cell division cycle 16-like protein. (622 aa)
RANBP2E3 SUMO-protein ligase RanBP2. (2133 aa)
INCENPInner centromere protein isoform A. (888 aa)
NNF1Nnf1 protein. (197 aa)
INCENPLInner centromere protein-like isoform D. (1075 aa)
ANAPC16Anaphase-promoting complex subunit 16. (110 aa)
ZW10Centromere/kinetochore zw10-like protein. (751 aa)
RCC2Protein RCC2. (435 aa)
CLASP2Uncharacterized protein. (1568 aa)
NSL1Kinetochore-associated NSL1-like protein. (274 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (479 aa)
GLTSCR1-1Glioma tumor suppressor candidate region 1 protein isoform C. (1814 aa)
BUB3Mitotic checkpoint protein BUB3. (384 aa)
CENPFCentromere protein F. (2477 aa)
CDC20Cell division cycle 20-like protein. (427 aa)
ERCC6LDNA excision repair protein ERCC-6-like. (694 aa)
DYNC1H1Uncharacterized protein. (4633 aa)
PPP2R5C-2Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (602 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (796 aa)
CENPPCentromere protein P. (150 aa)
CENPPLCentromere protein P. (82 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (740 aa)
CDC27Cell division cycle 27-like protein. (834 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (859 aa)
UBE2CUbiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
CENPHCentromere protein H. (240 aa)
ANAPC15Anaphase-promoting complex subunit 15. (94 aa)
ITGB3BPCentromere protein R. (181 aa)
SPC24Kinetochore protein Spc24. (207 aa)
NUP43Nucleoporin Nup43. (379 aa)
CENPNCentromere protein N. (347 aa)
CENPICentromere protein I. (736 aa)
ZWINTZW10 interactor. (352 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (626 aa)
ANAPC11Anaphase-promoting complex subunit 11. (98 aa)
ANAPC7Anaphase-promoting complex subunit 7. (608 aa)
ANAPC5Anaphase-promoting complex subunit 5. (756 aa)
CLIP1CAP-Gly domain-containing linker protein 1 isoform A. (1893 aa)
KNTC1Kinetochore-associated protein 1. (2218 aa)
NUDC-1Nuclear migration protein nudC isoform A. (346 aa)
RANGAP1Ran GTPase-activating protein 1. (568 aa)
NUP37Nucleoporin Nup37. (341 aa)
CENPMCentromere protein M. (177 aa)
CDCA8Borealin. (234 aa)
SEH1LNucleoporin SEH1; Belongs to the WD repeat SEC13 family. (360 aa)
NDC80Kinetochore NDC80-like protein. (639 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (140 aa)
CENPQ-1Centromere protein Q isoform A. (220 aa)
BIRC5BBaculoviral IAP repeat-containing 5b. (171 aa)
SGOL2Shugoshin-like 2. (356 aa)
Y1Q_0008603Uncharacterized protein. (483 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (489 aa)
CLIP2Uncharacterized protein. (1015 aa)
MIS12MIS12-like protein. (188 aa)
DYNLL2Dynein light chain. (77 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
DYNLL1Dynein light chain. (123 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (620 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform B. (1005 aa)
NDE1Nuclear distribution nudE-like protein 1. (323 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (179 aa)
CDC20B-1Cell division cycle 20-like protein B isoform A. (555 aa)
Y1Q_0009945Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
CENPKCentromere protein K. (290 aa)
SKA1-1Spindle and kinetochore-associated protein 1 isoform A. (315 aa)
BUB1BMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (997 aa)
CASC5Protein CASC5 isoform A. (2158 aa)
PPP2R5BSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (493 aa)
MTUS2-1Microtubule-associated tumor suppressor candidate 2-like isoform A. (1045 aa)
MAPRE3-1Microtubule-associated protein RP/EB family member 3 isoform B. (338 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (532 aa)
SGOL1Shugoshin-like 1 isoform A. (447 aa)
DYNC1I1WD_REPEATS_REGION domain-containing protein. (675 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2. (325 aa)
NUP160Nuclear pore complex protein Nup160. (1373 aa)
CKAP5Cytoskeleton-associated protein 5. (1360 aa)
SEC13SEC13-like protein; Belongs to the WD repeat SEC13 family. (320 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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