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RECQL4 | ATP-dependent DNA helicase Q4 isoform A. (1385 aa) | ||||
NUDC-1 | Nuclear migration protein nudC isoform A. (346 aa) | ||||
Y1Q_0016099 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
RANGAP1 | Ran GTPase-activating protein 1. (568 aa) | ||||
WEE2-1 | Wee1-like protein kinase. (592 aa) | ||||
NUP37 | Nucleoporin Nup37. (341 aa) | ||||
MCM5 | DNA helicase; Belongs to the MCM family. (773 aa) | ||||
CENPM | Centromere protein M. (177 aa) | ||||
PSMC4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) | ||||
CHEK1 | Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (471 aa) | ||||
CDCA8 | Borealin. (234 aa) | ||||
PIEZO2-2 | Piezo-type mechanosensitive ion channel component. (2595 aa) | ||||
SEH1L | Nucleoporin SEH1; Belongs to the WD repeat SEC13 family. (360 aa) | ||||
ANKRD12 | Ankyrin repeat domain-containing protein 12. (761 aa) | ||||
NDC80 | Kinetochore NDC80-like protein. (639 aa) | ||||
Y1Q_0001015 | Reverse transcriptase domain-containing protein. (170 aa) | ||||
BIRC5 | Baculoviral IAP repeat-containing protein 5. (140 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (772 aa) | ||||
CENPQ-1 | Centromere protein Q isoform A. (220 aa) | ||||
ATR | Serine/threonine-protein kinase ATR isoform A; Belongs to the PI3/PI4-kinase family. (2392 aa) | ||||
BARD1 | BRCA1-associated RING domain protein 1 isoform B. (792 aa) | ||||
BIRC5B | Baculoviral IAP repeat-containing 5b. (171 aa) | ||||
ORC2 | Origin recognition complex subunit 2. (569 aa) | ||||
SGOL2 | Shugoshin-like 2. (356 aa) | ||||
PSMC5 | Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
Y1Q_0008603 | Uncharacterized protein. (483 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1. (232 aa) | ||||
Y1Q_0009388 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) | ||||
YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (267 aa) | ||||
DYNC1LI2 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (489 aa) | ||||
CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa) | ||||
CLIP2 | Uncharacterized protein. (1015 aa) | ||||
MIS12 | MIS12-like protein. (188 aa) | ||||
DYNLL2 | Dynein light chain. (77 aa) | ||||
PAFAH1B1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa) | ||||
WRN | Werner syndrome ATP-dependent helicase. (1443 aa) | ||||
RFC2 | Replication factor C subunit 2. (340 aa) | ||||
YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
DYNLL1 | Dynein light chain. (123 aa) | ||||
YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (247 aa) | ||||
RFC5 | Replication factor C subunit 5. (336 aa) | ||||
CDK3 | Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (348 aa) | ||||
NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (620 aa) | ||||
PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (441 aa) | ||||
MEIOB | Meiosis-specific with OB domain-containing protein isoform A. (516 aa) | ||||
TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (983 aa) | ||||
MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1 isoform B. (1005 aa) | ||||
RMI2 | RecQ-mediated genome instability protein 2. (75 aa) | ||||
NDE1 | Nuclear distribution nudE-like protein 1. (323 aa) | ||||
Y1Q_0005128 | Proteasome subunit beta. (277 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa) | ||||
PIEZO1 | Piezo-type mechanosensitive ion channel component 1. (229 aa) | ||||
ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (179 aa) | ||||
Y1Q_0004667 | Uncharacterized protein. (92 aa) | ||||
CCNE2-1 | G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (410 aa) | ||||
YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (319 aa) | ||||
Y1Q_0017935 | Reverse transcriptase domain-containing protein. (228 aa) | ||||
CDC20B-1 | Cell division cycle 20-like protein B isoform A. (555 aa) | ||||
Y1Q_0009945 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa) | ||||
CENPK | Centromere protein K. (290 aa) | ||||
RAD1 | Cell cycle checkpoint protein RAD1. (253 aa) | ||||
SKA1-1 | Spindle and kinetochore-associated protein 1 isoform A. (315 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) | ||||
Y1Q_0014292 | Piezo_RRas_bdg domain-containing protein. (81 aa) | ||||
Y1Q_0020715 | Piezo_RRas_bdg domain-containing protein. (220 aa) | ||||
BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta. (997 aa) | ||||
CASC5 | Protein CASC5 isoform A. (2158 aa) | ||||
CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa) | ||||
PPP2R5B | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (493 aa) | ||||
RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (392 aa) | ||||
ORC3 | Origin recognition complex subunit 3 isoform A. (713 aa) | ||||
BLM | Bloom syndrome protein. (1213 aa) | ||||
MTUS2-1 | Microtubule-associated tumor suppressor candidate 2-like isoform A. (1045 aa) | ||||
ORC6 | Origin recognition complex subunit 6. (267 aa) | ||||
MAPRE3-1 | Microtubule-associated protein RP/EB family member 3 isoform B. (338 aa) | ||||
DYNC1LI1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (532 aa) | ||||
ZNF385D-2 | U1-type domain-containing protein. (92 aa) | ||||
SGOL1 | Shugoshin-like 1 isoform A. (447 aa) | ||||
RPA3 | Replication protein A subunit. (120 aa) | ||||
DYNC1I1 | WD_REPEATS_REGION domain-containing protein. (675 aa) | ||||
CNTD2 | Cyclin N-terminal domain-containing protein 2; Belongs to the cyclin family. (232 aa) | ||||
CCNA1-1 | Cyclin-A1 isoform C; Belongs to the cyclin family. (445 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (861 aa) | ||||
Y1Q_0003907 | MCM domain-containing protein. (120 aa) | ||||
Y1Q_0003896 | Reverse transcriptase domain-containing protein. (253 aa) | ||||
MAPRE2 | Microtubule-associated protein RP/EB family member 2. (325 aa) | ||||
UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2. (144 aa) | ||||
NUP160 | Nuclear pore complex protein Nup160. (1373 aa) | ||||
CKAP5 | Cytoskeleton-associated protein 5. (1360 aa) | ||||
PSMB9 | Proteasome subunit beta. (216 aa) | ||||
PSMB8 | Proteasome subunit beta. (282 aa) | ||||
YWHAE | 14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa) | ||||
TP53BP1-1 | Tumor suppressor p53-binding protein 1 isoform A. (2124 aa) | ||||
PSMD6 | 26S proteasome non-ATPase regulatory subunit 6. (348 aa) | ||||
SEC13 | SEC13-like protein; Belongs to the WD repeat SEC13 family. (320 aa) | ||||
RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (589 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (888 aa) | ||||
TM4SF19 | Transmembrane 4 L6 family member 19. (205 aa) | ||||
RCC2 | Protein RCC2. (435 aa) | ||||
CENPC | Centromere protein C. (613 aa) | ||||
Y1Q_0002109 | Uncharacterized protein. (179 aa) | ||||
CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) | ||||
NUF2 | Kinetochore protein Nuf2. (553 aa) | ||||
CENPL | Centromere protein L isoform A. (341 aa) | ||||
RFWD2 | E3 ubiquitin-protein ligase RFWD2 isoform A. (796 aa) | ||||
MAPRE1 | Microtubule-associated protein RP/EB family member 1. (286 aa) | ||||
CDC23 | Cell division cycle 23-like protein isoform B. (585 aa) | ||||
TDRD3 | Tudor domain-containing protein 3 isoform A. (743 aa) | ||||
RCBTB1-2 | BTB domain-containing protein. (595 aa) | ||||
RCBTB1 | RCC1 and BTB domain-containing protein 1. (566 aa) | ||||
AHCTF1 | Protein ELYS. (1901 aa) | ||||
EXO1 | Exonuclease 1. (775 aa) | ||||
MCM8 | DNA helicase MCM8; Belongs to the MCM family. (795 aa) | ||||
XPO1 | Exportin-1. (1001 aa) | ||||
RPS27A | Ubiquitin-40S ribosomal protein S27a. (156 aa) | ||||
PSME4 | Proteasome activator complex subunit 4. (1808 aa) | ||||
UBE2S | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (215 aa) | ||||
PSMB7 | Proteasome subunit beta. (274 aa) | ||||
PSMD5-1 | 26S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa) | ||||
CDC26 | Anaphase-promoting complex subunit CDC26. (84 aa) | ||||
ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (675 aa) | ||||
Y1Q_0003135 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (127 aa) | ||||
PPP2R5D | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (596 aa) | ||||
PPP2R1A | Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa) | ||||
CDKN1C | Cyclin-dependent kinase inhibitor 1C. (223 aa) | ||||
WEE1 | Wee1-like protein kinase. (1114 aa) | ||||
PSMA1 | Proteasome subunit alpha type. (261 aa) | ||||
KIF18A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa) | ||||
EXD2 | Exonuclease 3'-5' domain-containing protein 2 isoform A. (621 aa) | ||||
CKAP5-2 | Uncharacterized protein. (2029 aa) | ||||
PSMC3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa) | ||||
MDM4 | Protein Mdm4. (513 aa) | ||||
CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa) | ||||
Y1Q_0001599 | Reverse transcriptase domain-containing protein. (173 aa) | ||||
HYKK | Proteasome endopeptidase complex. (600 aa) | ||||
ZWILCH | Zwilch-like protein. (568 aa) | ||||
RMI1 | RecQ-mediated genome instability protein 1. (524 aa) | ||||
ERCC6L2 | DNA excision repair protein ERCC-6-like 2. (1396 aa) | ||||
RAD50 | DNA repair protein RAD50. (1448 aa) | ||||
PPP2CA | Serine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa) | ||||
RFC4 | Replication factor C subunit 4. (364 aa) | ||||
PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa) | ||||
CDC7-1 | Cell division cycle 7-related protein kinase isoform B. (672 aa) | ||||
ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (949 aa) | ||||
MCM9L | DNA helicase MCM9. (752 aa) | ||||
MCM9 | DNA helicase MCM9; Belongs to the MCM family. (463 aa) | ||||
NUP133 | Nuclear pore complex protein Nup133. (1154 aa) | ||||
PPP2R5E | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (515 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (256 aa) | ||||
BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1. (1069 aa) | ||||
ANAPC1 | Anaphase-promoting complex subunit 1. (1942 aa) | ||||
NUP98 | Nuclear pore complex protein Nup98-Nup96 isoform A. (1816 aa) | ||||
CLASP1 | CLIP-associating protein 1 isoform B. (1464 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (822 aa) | ||||
ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) | ||||
PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (460 aa) | ||||
DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2 isoform C. (726 aa) | ||||
SPC25 | Kinetochore protein Spc25. (269 aa) | ||||
ZNF385B | Zinc finger protein 385B isoform B. (505 aa) | ||||
Y1Q_0015745 | Uncharacterized protein. (257 aa) | ||||
HIST1H2BF | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
HIST2H2BE | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
Y1Q_0020100 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
Y1Q_0020098 | Histone H2B; Belongs to the histone H2B family. (166 aa) | ||||
UBE2N | Ubiquitin-conjugating enzyme E2 N. (112 aa) | ||||
Y1Q_0022362 | Histone H2B.3-like. (135 aa) | ||||
44G24.1 | Histone H2B.3; Belongs to the histone H2B family. (142 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa) | ||||
ANAPC15 | Anaphase-promoting complex subunit 15. (94 aa) | ||||
PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (257 aa) | ||||
FAM38B | Piezo-type mechanosensitive ion channel component 2. (797 aa) | ||||
RNF169 | E3 ubiquitin-protein ligase RNF169 isoform B. (626 aa) | ||||
RAD17 | Cell cycle checkpoint protein RAD17. (696 aa) | ||||
SLF1 | Ankyrin repeat domain-containing protein 32. (825 aa) | ||||
ANKRD31-1 | Putative ankyrin repeat domain-containing protein 31 isoform C. (1142 aa) | ||||
CENPH | Centromere protein H. (240 aa) | ||||
WDR41 | WD repeat-containing protein 41. (459 aa) | ||||
Y1Q_0010122 | Uncharacterized protein. (300 aa) | ||||
CCNB1 | G2/mitotic-specific cyclin-B1 isoform B; Belongs to the cyclin family. (411 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) | ||||
CLSPN | Claspin. (1316 aa) | ||||
RBBP8-1 | DNA endonuclease RBBP8 isoform B. (936 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
BABAM1 | BRISC and BRCA1-A complex member 1. (325 aa) | ||||
UBE2C | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) | ||||
MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (494 aa) | ||||
NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (859 aa) | ||||
CCNA2 | Cyclin-A2; Belongs to the cyclin family. (382 aa) | ||||
MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A. (205 aa) | ||||
PKMYT1 | Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase. (554 aa) | ||||
Y1Q_0012805 | Histone H2B; Belongs to the histone H2B family. (118 aa) | ||||
PSMC6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) | ||||
Y1Q_0014479 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa) | ||||
ZNF385C-1 | Zinc finger protein 385C isoform A. (1099 aa) | ||||
Y1Q_0018383 | Histone H2B-like; Belongs to the histone H2B family. (152 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (549 aa) | ||||
PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (518 aa) | ||||
HUS1 | Checkpoint protein; Belongs to the HUS1 family. (284 aa) | ||||
CDC27 | Cell division cycle 27-like protein. (834 aa) | ||||
KIF2C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (740 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein. (832 aa) | ||||
CENPPL | Centromere protein P. (82 aa) | ||||
CENPP | Centromere protein P. (150 aa) | ||||
ATRIP | ATR-interacting protein. (672 aa) | ||||
ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (796 aa) | ||||
NSD2 | Uncharacterized protein. (1370 aa) | ||||
PSMC1 | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa) | ||||
PPP2R5C-2 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (602 aa) | ||||
BRCC3 | Lys-63-specific deubiquitinase BRCC36. (261 aa) | ||||
DYNC1H1 | Uncharacterized protein. (4633 aa) | ||||
CCNB3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (435 aa) | ||||
Y1Q_0014681 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (119 aa) | ||||
ERCC6L | DNA excision repair protein ERCC-6-like. (694 aa) | ||||
ATM | Non-specific serine/threonine protein kinase. (3063 aa) | ||||
CDKN1D | Cyclin-dependent kinase inhibitor 1D. (153 aa) | ||||
CDKN1B | Cyclin-dependent kinase inhibitor 1B. (131 aa) | ||||
RHNO1 | RAD9. (261 aa) | ||||
CDC20 | Cell division cycle 20-like protein. (427 aa) | ||||
PSMB3 | Proteasome subunit beta. (205 aa) | ||||
PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (521 aa) | ||||
ANKRD11 | Ankyrin repeat domain-containing protein 11. (2899 aa) | ||||
CENPF | Centromere protein F. (2477 aa) | ||||
BUB3 | Mitotic checkpoint protein BUB3. (384 aa) | ||||
GLTSCR1-1 | Glioma tumor suppressor candidate region 1 protein isoform C. (1814 aa) | ||||
CTNNA3 | Catenin alpha-3. (157 aa) | ||||
CMTR1-1 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (521 aa) | ||||
PPP2R5C | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (479 aa) | ||||
NSL1 | Kinetochore-associated NSL1-like protein. (274 aa) | ||||
Y1Q_0007301 | Piezo-type mechanosensitive ion channel component 1-like. (506 aa) | ||||
BRE | BRCA1-A complex subunit BRE. (398 aa) | ||||
TOPBP1 | DNA topoisomerase 2-binding protein 1. (1514 aa) | ||||
CLASP2 | Uncharacterized protein. (1568 aa) | ||||
PSMF1 | Proteasome inhibitor PI31 subunit. (273 aa) | ||||
Y1Q_0016180 | Uncharacterized protein. (89 aa) | ||||
MRE11A | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (720 aa) | ||||
Y1Q_0012919 | Uncharacterized protein. (87 aa) | ||||
Y1Q_0018179 | PIEZO domain-containing protein. (254 aa) | ||||
CENPO | Centromere protein O. (351 aa) | ||||
DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1052 aa) | ||||
ZW10 | Centromere/kinetochore zw10-like protein. (751 aa) | ||||
ANAPC16 | Anaphase-promoting complex subunit 16. (110 aa) | ||||
YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (300 aa) | ||||
PIEZO2 | Piezo-type mechanosensitive ion channel component. (2510 aa) | ||||
PSMA7 | Proteasome subunit alpha type. (248 aa) | ||||
INCENPL | Inner centromere protein-like isoform D. (1075 aa) | ||||
NNF1 | Nnf1 protein. (197 aa) | ||||
INCENP | Inner centromere protein isoform A. (888 aa) | ||||
PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) | ||||
RANBP2 | E3 SUMO-protein ligase RanBP2. (2133 aa) | ||||
CDC16 | Cell division cycle 16-like protein. (622 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (664 aa) | ||||
PIAS4 | E3 SUMO-protein ligase PIAS4. (541 aa) | ||||
DSN1 | Kinetochore-associated DSN1-like protein. (350 aa) | ||||
NDEL1 | Nuclear distribution protein nudE-like 1. (369 aa) | ||||
KXD1 | KxDL motif-containing protein 1. (293 aa) | ||||
PSMB6 | Proteasome subunit beta. (227 aa) | ||||
Y1Q_0000043 | Uncharacterized protein. (73 aa) | ||||
KNTC1 | Kinetochore-associated protein 1. (2218 aa) | ||||
Y1Q_0006757 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa) | ||||
HIST1H4D | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
CLIP1 | CAP-Gly domain-containing linker protein 1 isoform A. (1893 aa) | ||||
CDC45 | Cell division control 45-like protein. (501 aa) | ||||
RAD9B-1 | Cell cycle checkpoint control protein RAD9B isoform B. (364 aa) | ||||
SCARB1 | Scavenger receptor class B member 1 isoform A. (959 aa) | ||||
ANAPC5 | Anaphase-promoting complex subunit 5. (756 aa) | ||||
ANAPC7 | Anaphase-promoting complex subunit 7. (608 aa) | ||||
PSMD9-1 | 26S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa) | ||||
ANAPC11 | Anaphase-promoting complex subunit 11. (98 aa) | ||||
SPDL1 | Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (626 aa) | ||||
PSMB5 | Proteasome subunit beta type-5. (211 aa) | ||||
ZWINT | ZW10 interactor. (352 aa) | ||||
PSMB11 | Proteasome subunit beta. (261 aa) | ||||
PSMC2 | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) | ||||
MCM10 | MCM10-like protein. (868 aa) | ||||
ORC5 | Origin recognition complex subunit 5. (420 aa) | ||||
GTSE1 | G2 and S phase-expressed protein 1. (747 aa) | ||||
PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (322 aa) | ||||
HIST1H2B5L | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
PSMD10 | 26S proteasome non-ATPase regulatory subunit 10. (226 aa) | ||||
CENPI | Centromere protein I. (736 aa) | ||||
CENPN | Centromere protein N. (347 aa) | ||||
PSME1 | Proteasome activator complex subunit 1. (150 aa) | ||||
PSME2 | Proteasome activator complex subunit 2. (242 aa) | ||||
NUP43 | Nucleoporin Nup43. (379 aa) | ||||
SPC24 | Kinetochore protein Spc24. (207 aa) | ||||
SFN | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (246 aa) | ||||
CHEK2 | Serine/threonine-protein kinase Chk2 isoform B. (433 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (252 aa) | ||||
ITGB3BP | Centromere protein R. (181 aa) |