45 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RBBP4	Histone-binding protein RBBP4. (424 aa)
	ERCC3	TFIIH basal transcription factor complex helicase XPB subunit. (779 aa)
	TBPL2	TATA box-binding protein-like protein 2. (331 aa)
	GTF2H5	General transcription factor IIH subunit 5. (115 aa)
	TBP	TATA-box-binding protein. (301 aa)
	MTA2	Uncharacterized protein. (676 aa)
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (161 aa)
	ZNRD1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (404 aa)
	GTF2H1	L-lactate dehydrogenase. (910 aa)
	POLR1B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1078 aa)
	CHD3	Chromodomain-helicase-DNA-binding protein 3. (1920 aa)
	TTF1	Transcription termination factor 1. (476 aa)
	POLR1C	DNA-directed RNA polymerases I and III subunit RPAC1. (346 aa)
	ERCC6	DNA excision repair protein ERCC-6. (1491 aa)
	GATAD2A	Transcriptional repressor p66-alpha isoform C. (621 aa)
	RBBP4-2	WD_REPEATS_REGION domain-containing protein. (425 aa)
	TWISTNB	DNA-directed RNA polymerase I subunit RPA43. (317 aa)
	ERCC2	TFIIH basal transcription factor complex helicase XPD subunit. (795 aa)
	CD3EAP	DNA-directed RNA polymerase I subunit RPA34. (226 aa)
	TAF1C	TATA box-binding protein-associated factor RNA polymerase I subunit C. (117 aa)
	RRN3	RNA polymerase I-specific transcription initiation factor RRN3. (617 aa)
	CHD5	Uncharacterized protein. (1864 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	CHD3-2	Uncharacterized protein. (1966 aa)
	TAF1B	TATA box-binding protein-associated factor RNA polymerase I subunit B. (592 aa)
	POLR1E	DNA-directed RNA polymerase I subunit RPA49. (417 aa)
	POLR2F	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
	POLR2L-2	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (74 aa)
	DMTF1	Cyclin-D-binding Myb-like transcription factor 1 isoform B. (804 aa)
	GTF2H3	General transcription factor IIH subunit 3. (328 aa)
	MTA1-2	Uncharacterized protein. (694 aa)
	ACRC-1	Acidic repeat-containing protein isoform B. (498 aa)
	AIRE	Autoimmune regulator isoform B. (519 aa)
	POLR2L-1	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (104 aa)
	POLR2E	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (231 aa)
	TAF1D	TATA box-binding protein-associated factor RNA polymerase I subunit D. (330 aa)
	TAF1A-1	TATA box-binding protein-associated factor RNA polymerase I subunit A isoform B. (454 aa)
	MTA1	Metastasis-associated protein MTA1. (590 aa)
	POLR1A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1689 aa)
	UBTF	Nucleolar transcription factor 1 isoform B. (711 aa)
	CDK7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	GTF2H2	General transcription factor IIH subunit. (395 aa)
	CCNH	Cyclin-H; Belongs to the cyclin family. (247 aa)
	GATAD2B	Transcriptional repressor p66-beta isoform B. (634 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACRC-1	CD3EAP	A0A151NSZ0	A0A151MYN9	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerase I subunit RPA34.	0.606
ACRC-1	DMTF1	A0A151NSZ0	A0A151NPK9	Acidic repeat-containing protein isoform B.	Cyclin-D-binding Myb-like transcription factor 1 isoform B.	0.445
ACRC-1	ERCC2	A0A151NSZ0	A0A151MYN4	Acidic repeat-containing protein isoform B.	TFIIH basal transcription factor complex helicase XPD subunit.	0.508
ACRC-1	ERCC6	A0A151NSZ0	A0A151MKX5	Acidic repeat-containing protein isoform B.	DNA excision repair protein ERCC-6.	0.524
ACRC-1	GTF2H4	A0A151NSZ0	A0A151M5U1	Acidic repeat-containing protein isoform B.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.534
ACRC-1	POLR1A	A0A151NSZ0	A0A151P9G1	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.664
ACRC-1	POLR1B	A0A151NSZ0	A0A151MCN9	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.636
ACRC-1	POLR1C	A0A151NSZ0	A0A151MHQ6	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerases I and III subunit RPAC1.	0.517
ACRC-1	POLR1E	A0A151NSZ0	A0A151NDY5	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerase I subunit RPA49.	0.671
ACRC-1	POLR2H	A0A151NSZ0	A0A151M5C7	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.525
ACRC-1	RRN3	A0A151NSZ0	A0A151N1M3	Acidic repeat-containing protein isoform B.	RNA polymerase I-specific transcription initiation factor RRN3.	0.718
ACRC-1	TAF1C	A0A151NSZ0	A0A151MZL2	Acidic repeat-containing protein isoform B.	TATA box-binding protein-associated factor RNA polymerase I subunit C.	0.664
ACRC-1	TAF1D	A0A151NSZ0	A0A151P295	Acidic repeat-containing protein isoform B.	TATA box-binding protein-associated factor RNA polymerase I subunit D.	0.880
ACRC-1	TBP	A0A151NSZ0	A0A151M2N1	Acidic repeat-containing protein isoform B.	TATA-box-binding protein.	0.717
ACRC-1	TBPL2	A0A151NSZ0	A0A151M1X8	Acidic repeat-containing protein isoform B.	TATA box-binding protein-like protein 2.	0.717
ACRC-1	TTF1	A0A151NSZ0	A0A151MFN5	Acidic repeat-containing protein isoform B.	Transcription termination factor 1.	0.445
ACRC-1	TWISTNB	A0A151NSZ0	A0A151MQG1	Acidic repeat-containing protein isoform B.	DNA-directed RNA polymerase I subunit RPA43.	0.518
AIRE	ERCC6	A0A151NUV3	A0A151MKX5	Autoimmune regulator isoform B.	DNA excision repair protein ERCC-6.	0.438
AIRE	GATAD2A	A0A151NUV3	A0A151MM98	Autoimmune regulator isoform B.	Transcriptional repressor p66-alpha isoform C.	0.765
AIRE	GATAD2B	A0A151NUV3	A0A151PIY7	Autoimmune regulator isoform B.	Transcriptional repressor p66-beta isoform B.	0.765