STRINGSTRING
TIAM2 TIAM2 PSEN1-1 PSEN1-1 TRIO TRIO ARHGEF39 ARHGEF39 OTULIN OTULIN ARHGEF1L ARHGEF1L MAG MAG FAM105A FAM105A Y1Q_0000250 Y1Q_0000250 UBE2D1 UBE2D1 FAS FAS ARHGEF28 ARHGEF28 BIRC7-1 BIRC7-1 ARHGEF1A ARHGEF1A MCF2L MCF2L Y1Q_0006163 Y1Q_0006163 ARHGEF6 ARHGEF6 RBCK1 RBCK1 Y1Q_0013240 Y1Q_0013240 TAB3 TAB3 SPATA13 SPATA13 KXD1 KXD1 NGEF NGEF SCARB1 SCARB1 ULK1A ULK1A PSENEN PSENEN Y1Q_0002396 Y1Q_0002396 ARHGEF40 ARHGEF40 UBE2D2 UBE2D2 ARHGEF12 ARHGEF12 NET1-2 NET1-2 OPTN OPTN ARHGEF9 ARHGEF9 CCDC71L-1 CCDC71L-1 XIAP XIAP RNF31 RNF31 ARHGEF10 ARHGEF10 VAV3 VAV3 ARHGEF11 ARHGEF11 NFKBIA NFKBIA ITGB3BP ITGB3BP TAB1 TAB1 FGD4 FGD4 PRDM4 PRDM4 RIPK1 RIPK1 Y1Q_0014883 Y1Q_0014883 IKBKB-2 IKBKB-2 SPPL2B SPPL2B BAG4 BAG4 ARHGEF26 ARHGEF26 CASP8-1 CASP8-1 CASP10 CASP10 Y1Q_0013741 Y1Q_0013741 ULK2 ULK2 CASP18 CASP18 CFLAR CFLAR FGD2 FGD2 SMPD2 SMPD2 ADAM17 ADAM17 SHRPRBCK1R SHRPRBCK1R Y1Q_0010566 Y1Q_0010566 MCF2-2 MCF2-2 ARHGEF6-2 ARHGEF6-2 STUB1 STUB1 AATF AATF Y1Q_0012019 Y1Q_0012019 MIB2 MIB2 Y1Q_0006107 Y1Q_0006107 ARHGEF16 ARHGEF16 SOS1-1 SOS1-1 GNA13 GNA13 FGD3 FGD3 NET1 NET1 C1GALT1A C1GALT1A TGM3-2 TGM3-2 NRADD NRADD GNB2L1 GNB2L1 TGM3 TGM3 MAP3K7 MAP3K7 Y1Q_0016612 Y1Q_0016612 CYLD CYLD TAX1BP1 TAX1BP1 IKBKG IKBKG NSMAF NSMAF SMPD3 SMPD3 CLIP3-2 CLIP3-2 TRADD TRADD RIPK3L RIPK3L Y1Q_0020784 Y1Q_0020784 Y1Q_0023273 Y1Q_0023273 ARHGEF19 ARHGEF19 ARHGEF10L ARHGEF10L ARHGEF38 ARHGEF38 RPS27A RPS27A Y1Q_0020621 Y1Q_0020621 TRAF1-1 TRAF1-1 VAV2 VAV2 TRAF2 TRAF2 WDR31 WDR31 ITSN1-2 ITSN1-2 TIAM1 TIAM1 TNFRSF1A TNFRSF1A TNFRSFA TNFRSFA TRAF6 TRAF6 MADD MADD IKBKE IKBKE MAPKAPK3 MAPKAPK3 APH1A-1 APH1A-1 LINGO1 LINGO1 SPPL2A SPPL2A AKAP13-1 AKAP13-1 ARHGEF2 ARHGEF2 NCSTN NCSTN SQSTM1 SQSTM1 ARHGEF37 ARHGEF37 ECT2 ECT2 TNFSF10 TNFSF10 MCF2 MCF2 ARHGEF25 ARHGEF25 UBE2L3 UBE2L3 USP21 USP21 VAV3-2 VAV3-2 TNFAIP3 TNFAIP3 ECT2L ECT2L SOS1-2 SOS1-2 BCL2L11-1 BCL2L11-1 ARHGEF33-1 ARHGEF33-1 KALRN KALRN Y1Q_0011504 Y1Q_0011504 SESTD1 SESTD1 Y1Q_0021018 Y1Q_0021018 TMEM198 TMEM198 CASP14-2 CASP14-2 ARHGEF40L ARHGEF40L ARHGEF17 ARHGEF17 NAIP NAIP Y1Q_0004030 Y1Q_0004030 Y1Q_0010619 Y1Q_0010619 IKBKB IKBKB NGF NGF RIPK2 RIPK2 TBK1 TBK1 ARHGEF11-2 ARHGEF11-2 MYD88 MYD88 OTUD1 OTUD1 CASP3 CASP3 CYLDL CYLDL ARHGEF5 ARHGEF5 Y1Q_0007346 Y1Q_0007346 BIRC2 BIRC2 TNFRSF10B TNFRSF10B NGFR NGFR USP2 USP2 CLIP3 CLIP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TIAM2Uncharacterized protein. (1768 aa)
PSEN1-1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
TRIOUncharacterized protein. (3024 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (342 aa)
OTULINUbiquitin thioesterase otulin isoform B. (480 aa)
ARHGEF1LRho guanine nucleotide exchange factor 1 isoform A. (930 aa)
MAGMyelin-associated glycoprotein. (663 aa)
FAM105AInactive ubiquitin thioesterase FAM105A. (371 aa)
Y1Q_0000250Uncharacterized protein. (718 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (197 aa)
FASTumor necrosis factor receptor superfamily member 6. (341 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28 isoform B. (1520 aa)
BIRC7-1Baculoviral IAP repeat-containing protein 7 isoform A. (309 aa)
ARHGEF1ARho guanine nucleotide exchange factor 2 isoform B. (970 aa)
MCF2LUncharacterized protein. (1170 aa)
Y1Q_0006163betaPIX_CC domain-containing protein. (231 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6 isoform B. (540 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1 isoform B. (521 aa)
Y1Q_0013240Uncharacterized protein. (82 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (368 aa)
SPATA13Spermatogenesis-associated protein 13. (1708 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
NGEFEphexin-1. (569 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
ULK1AUnc-51 like autophagy activating kinase 1a isoform A. (1048 aa)
PSENENGamma-secretase subunit PEN-2 isoform A. (81 aa)
Y1Q_0002396USP domain-containing protein; Belongs to the peptidase C19 family. (85 aa)
ARHGEF40Rho guanine nucleotide exchange factor 40. (294 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform A. (1601 aa)
NET1-2Uncharacterized protein. (556 aa)
OPTNOptineurin. (546 aa)
ARHGEF9Uncharacterized protein. (840 aa)
CCDC71L-1Coiled-coil domain-containing protein 71L isoform B. (79 aa)
XIAPE3 ubiquitin-protein ligase XIAP. (558 aa)
RNF31E3 ubiquitin-protein ligase RNF31. (955 aa)
ARHGEF10DH domain-containing protein. (1355 aa)
VAV3Guanine nucleotide exchange factor VAV3. (815 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11 isoform C. (1419 aa)
NFKBIANF-kappa-B inhibitor alpha. (299 aa)
ITGB3BPCentromere protein R. (181 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
FGD4Uncharacterized protein. (831 aa)
PRDM4PR domain zinc finger protein 4 isoform B. (863 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (699 aa)
Y1Q_0014883Transmembrane protein 198-like. (343 aa)
IKBKB-2Uncharacterized protein. (757 aa)
SPPL2BSignal peptide peptidase-like 2B. (607 aa)
BAG4BAG family molecular chaperone regulator 4. (387 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (590 aa)
CASP8-1Caspase-8 isoform B; Belongs to the peptidase C14A family. (462 aa)
CASP10Caspase-10 isoform B; Belongs to the peptidase C14A family. (489 aa)
Y1Q_0013741Ubiquitin carboxyl-terminal hydrolase 2-like; Belongs to the peptidase C19 family. (179 aa)
ULK2Serine/threonine-protein kinase ULK2. (1048 aa)
CASP18Initiator caspase; Belongs to the peptidase C14A family. (424 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (530 aa)
FGD2FYVE, RhoGEF and PH domain-containing protein 2. (696 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (409 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (836 aa)
SHRPRBCK1RRanBP-type and C3HC4-type zinc finger-containing protein 1 isoform A. (480 aa)
Y1Q_0010566RanBP-type and C3HC4-type zinc finger-containing protein 1-like. (155 aa)
MCF2-2Uncharacterized protein. (1034 aa)
ARHGEF6-2Uncharacterized protein. (785 aa)
STUB1E3 ubiquitin-protein ligase CHIP isoform A. (339 aa)
AATFProtein AATF. (571 aa)
Y1Q_0012019Uncharacterized protein. (105 aa)
MIB2Uncharacterized protein. (954 aa)
Y1Q_0006107Rho guanine nucleotide exchange factor 7. (376 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (628 aa)
SOS1-1Son of sevenless-like protein 1 isoform A. (1305 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (422 aa)
FGD3FYVE, RhoGEF and PH domain-containing protein 3. (917 aa)
NET1Neuroepithelial cell-transforming 1 protein isoform A. (591 aa)
C1GALT1AGlycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A. (432 aa)
TGM3-2Protein-glutamine gamma-glutamyltransferase E-like. (694 aa)
NRADDTumor necrosis factor receptor superfamily member 16. (408 aa)
GNB2L1Guanine nucleotide-binding protein subunit beta-2-like 1. (317 aa)
TGM3Protein-glutamine gamma-glutamyltransferase E isoform B. (757 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform A. (610 aa)
Y1Q_0016612Uncharacterized protein. (94 aa)
CYLDUncharacterized protein. (949 aa)
TAX1BP1Tax1-binding protein 1 isoform A. (904 aa)
IKBKGNF-kappa-B essential modulator. (542 aa)
NSMAFProtein FAN. (917 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (642 aa)
CLIP3-2Uncharacterized protein. (531 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (336 aa)
RIPK3LReceptor-interacting serine/threonine-protein kinase 2. (564 aa)
Y1Q_0020784Ubiquitin carboxyl-terminal hydrolase 2-like. (253 aa)
Y1Q_0023273Uncharacterized protein. (599 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (851 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10-like protein isoform B. (1322 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38 isoform B. (777 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
Y1Q_0020621DH domain-containing protein. (181 aa)
TRAF1-1TNF receptor-associated factor 1 isoform C. (723 aa)
VAV2Uncharacterized protein. (839 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (601 aa)
WDR31WD repeat-containing protein 31 isoform A. (363 aa)
ITSN1-2Uncharacterized protein. (492 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1471 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (412 aa)
TNFRSFATumor necrosis factor receptor superfamily member 6-like. (427 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
MADDMAP kinase-activating death domain protein isoform E. (1625 aa)
IKBKEUncharacterized protein. (1096 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (354 aa)
APH1A-1Gamma-secretase subunit APH-1A isoform A. (291 aa)
LINGO1Ig-like domain-containing protein. (606 aa)
SPPL2ASignal peptide peptidase-like 2A isoform B. (537 aa)
AKAP13-1A-kinase anchor protein 13 isoform B. (1730 aa)
ARHGEF2Rho guanine nucleotide exchange factor 2. (994 aa)
NCSTNNicastrin. (718 aa)
SQSTM1Sequestosome-1. (457 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (697 aa)
ECT2Protein ECT2 isoform A. (914 aa)
TNFSF10Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (295 aa)
MCF2Proto-oncogene DBL isoform D. (1306 aa)
ARHGEF25Rho guanine nucleotide exchange factor 25. (503 aa)
UBE2L3Ubiquitin-conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
USP21Ubiquitin carboxyl-terminal hydrolase. (458 aa)
VAV3-2Uncharacterized protein. (846 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (853 aa)
ECT2LEpithelial cell-transforming sequence 2 oncogene-like isoform A. (968 aa)
SOS1-2Son of sevenless-like protein. (1379 aa)
BCL2L11-1Bcl-2-like protein 11 isoform C. (178 aa)
ARHGEF33-1Rho guanine nucleotide exchange factor 33 isoform A. (769 aa)
KALRNTriple functional domain protein. (2926 aa)
Y1Q_0011504Uncharacterized protein. (742 aa)
SESTD1SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
Y1Q_0021018RanBP-type and C3HC4-type zinc finger-containing protein 1-like. (176 aa)
TMEM198Transmembrane protein 198. (250 aa)
CASP14-2Uncharacterized protein; Belongs to the peptidase C14A family. (249 aa)
ARHGEF40LRho guanine nucleotide exchange factor 40 isoform A. (1025 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17 isoform A. (1659 aa)
NAIPBaculoviral IAP repeat-containing protein 1 isoform A. (878 aa)
Y1Q_0004030Uncharacterized protein. (147 aa)
Y1Q_0010619Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (1690 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (730 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (329 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (561 aa)
TBK1Serine/threonine-protein kinase TBK1. (677 aa)
ARHGEF11-2Rho guanine nucleotide exchange factor 11-like. (99 aa)
MYD88Myeloid differentiation primary response protein MyD88. (203 aa)
OTUD1OTU domain-containing protein 1. (325 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (292 aa)
CYLDLUbiquitin carboxyl-terminal hydrolase CYLD-like; Belongs to the peptidase C19 family. (788 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5 isoform B. (1796 aa)
Y1Q_0007346TNF-related apoptosis inducing ligand-like protein; Belongs to the tumor necrosis factor family. (271 aa)
BIRC2Inhibitor of apoptosis protein. (493 aa)
TNFRSF10BTumor necrosis factor receptor superfamily member 10B. (394 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
USP2USP domain-containing protein. (105 aa)
CLIP3CAP-Gly domain-containing linker protein 3. (615 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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