STRINGSTRING
LRRK2 LRRK2 ELMOD3-1 ELMOD3-1 TGFB1I1 TGFB1I1 NRG4 NRG4 CCND1 CCND1 RPS27A RPS27A CRK CRK KHDRBS1 KHDRBS1 GPNMB GPNMB NRG3 NRG3 Y1Q_0005265 Y1Q_0005265 ERBB3 ERBB3 ELMO3-2 ELMO3-2 STAP2 STAP2 PXN PXN CCNE1 CCNE1 ERBB4 ERBB4 NRG1-1 NRG1-1 ELMOD2 ELMOD2 ELMO3 ELMO3 KRAS-2 KRAS-2 KRAS-1 KRAS-1 HBEGF-1 HBEGF-1 NRG2-2 NRG2-2 NRG2 NRG2 SCARB1 SCARB1 NONO NONO KXD1 KXD1 LPXN LPXN RNF222 RNF222 SOCS3 SOCS3 Y1Q_0006325 Y1Q_0006325 PTPN1 PTPN1 Y1Q_0017492 Y1Q_0017492 Y1Q_0017491 Y1Q_0017491 ELMO1-2 ELMO1-2 EGFR EGFR ELMO1-1 ELMO1-1 ARHGAP35 ARHGAP35 ERBB2 ERBB2 Y1Q_0011001 Y1Q_0011001 ELMOD1 ELMOD1 PSPC1 PSPC1 KHDRBS3-1 KHDRBS3-1 KHDRBS2 KHDRBS2 SFPQ SFPQ NRAS NRAS RASA1 RASA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2528 aa)
ELMOD3-1ELMO domain-containing protein 3 isoform A. (404 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein. (387 aa)
NRG4Pro-neuregulin-4, membrane-bound. (115 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
CRKAdapter molecule crk. (291 aa)
KHDRBS1KH domain-containing, RNA-binding, signal transduction-associated protein 1. (352 aa)
GPNMBTransmembrane glycoprotein NMB. (575 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform A. (353 aa)
Y1Q_0005265Uncharacterized protein. (212 aa)
ERBB3Protein kinase domain-containing protein. (1303 aa)
ELMO3-2ELMO domain-containing protein. (1145 aa)
STAP2Signal-transducing adaptor protein 2 isoform A. (416 aa)
PXNPaxillin isoform C. (614 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa)
ERBB4Receptor protein-tyrosine kinase. (1335 aa)
NRG1-1Pro-neuregulin-1, membrane-bound isoform C. (636 aa)
ELMOD2ELMO domain-containing protein 2. (299 aa)
ELMO3Engulfment and cell motility protein 3 isoform A. (673 aa)
KRAS-2GTPase KRas. (219 aa)
KRAS-1GTPase KRas. (215 aa)
HBEGF-1Proheparin-binding EGF-like growth factor isoform B. (205 aa)
NRG2-2Uncharacterized protein. (261 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform isoform D. (675 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
NONONon-POU domain-containing octamer-binding protein. (618 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
LPXNLeupaxin. (388 aa)
RNF222RING finger protein 222. (238 aa)
SOCS3Suppressor of cytokine signaling 3. (196 aa)
Y1Q_0006325Uncharacterized protein. (188 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
Y1Q_0017492Protein kinase domain-containing protein. (493 aa)
Y1Q_0017491Uncharacterized protein. (138 aa)
ELMO1-2Engulfment and cell motility protein 1. (239 aa)
EGFRUncharacterized protein. (633 aa)
ELMO1-1Engulfment and cell motility protein 1. (519 aa)
ARHGAP35Rho GTPase-activating protein 35. (1196 aa)
ERBB2Receptor protein-tyrosine kinase. (1262 aa)
Y1Q_0011001Suppressor of cytokine signaling 3-like. (189 aa)
ELMOD1ELMO domain-containing protein 1 isoform A. (326 aa)
PSPC1Paraspeckle component 1 isoform A. (526 aa)
KHDRBS3-1KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform A. (416 aa)
KHDRBS2KH domain-containing, RNA-binding, signal transduction-associated protein 2. (348 aa)
SFPQSplicing factor, proline-and glutamine-rich isoform B. (717 aa)
NRASGTPase NRas. (189 aa)
RASA1Ras GTPase-activating protein 1. (904 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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