STRINGSTRING
PSMB2 PSMB2 CCNB1 CCNB1 PSMD8 PSMD8 PSMA3 PSMA3 PSMB4 PSMB4 PSMD4 PSMD4 HYKK HYKK CCNB2 CCNB2 PSMC3 PSMC3 PSMA1 PSMA1 PSMD5-1 PSMD5-1 PSMB7 PSMB7 PSME4 PSME4 RPS27A RPS27A MAPRE1 MAPRE1 PSMD6 PSMD6 PSMB8 PSMB8 PSMB9 PSMB9 CNTD2 CNTD2 CDK1 CDK1 TP53 TP53 PSMD1 PSMD1 Y1Q_0005128 Y1Q_0005128 PSMD12 PSMD12 TUBA1C TUBA1C PSMA5 PSMA5 TUBAL3 TUBAL3 PSMC5 PSMC5 Y1Q_0024551 Y1Q_0024551 PSMC4 PSMC4 Y1Q_0024323 Y1Q_0024323 Y1Q_0024324 Y1Q_0024324 PSMA6 PSMA6 PSME2 PSME2 PSME1 PSME1 PSMD10 PSMD10 PSMD7 PSMD7 GTSE1 GTSE1 ARHGEF3 ARHGEF3 TUBA8B TUBA8B PSMC2 PSMC2 Y1Q_0023492 Y1Q_0023492 PSMB11 PSMB11 PSMB5 PSMB5 Y1Q_0023503 Y1Q_0023503 Y1Q_0020178 Y1Q_0020178 PSMD14 PSMD14 Y1Q_0020177 Y1Q_0020177 PSMD9-1 PSMD9-1 PSMB6 PSMB6 PLK1 PLK1 PSMD13 PSMD13 PSMA7 PSMA7 PSMF1 PSMF1 PSMD3 PSMD3 PSMB3 PSMB3 PSMC1 PSMC1 PSMD11 PSMD11 PSMC6 PSMC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB2Proteasome subunit beta. (201 aa)
CCNB1G2/mitotic-specific cyclin-B1 isoform B; Belongs to the cyclin family. (411 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (257 aa)
PSMA3Proteasome subunit alpha type. (256 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
HYKKProteasome endopeptidase complex. (600 aa)
CCNB2G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
PSMD5-126S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
PSMB7Proteasome subunit beta. (274 aa)
PSME4Proteasome activator complex subunit 4. (1808 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (286 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (348 aa)
PSMB8Proteasome subunit beta. (282 aa)
PSMB9Proteasome subunit beta. (216 aa)
CNTD2Cyclin N-terminal domain-containing protein 2; Belongs to the cyclin family. (232 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
Y1Q_0005128Proteasome subunit beta. (277 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (441 aa)
TUBA1CTubulin alpha chain. (127 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
Y1Q_0024551Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
Y1Q_0024323Tubulin alpha-8 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (229 aa)
Y1Q_0024324Tubulin alpha-8 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (222 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
PSME1Proteasome activator complex subunit 1. (150 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
GTSE1G2 and S phase-expressed protein 1. (747 aa)
ARHGEF3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (223 aa)
TUBA8BTubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (295 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
Y1Q_0023492Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (206 aa)
PSMB11Proteasome subunit beta. (261 aa)
PSMB5Proteasome subunit beta type-5. (211 aa)
Y1Q_0023503Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (193 aa)
Y1Q_0020178Tubulin alpha chain-like. (151 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (460 aa)
Y1Q_0020177Uncharacterized protein. (70 aa)
PSMD9-126S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
PSMB6Proteasome subunit beta. (227 aa)
PLK1Serine/threonine-protein kinase PLK. (664 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (521 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (518 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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