STRINGSTRING
SYT4 SYT4 TGOLN2 TGOLN2 Y1Q_0011539 Y1Q_0011539 LRP6 LRP6 STAM STAM IGF2R IGF2R REPS1 REPS1 Y1Q_0024416 Y1Q_0024416 EPS15-2 EPS15-2 STON2 STON2 Y1Q_0006860 Y1Q_0006860 VAMP2-1 VAMP2-1 GPS1 GPS1 UBQLN4 UBQLN4 NEDD8 NEDD8 MCTP1 MCTP1 SH3GL3 SH3GL3 COPS2 COPS2 UBL7 UBL7 LRP4 LRP4 SYT9-2 SYT9-2 SYT8 SYT8 COPS7A COPS7A CD4 CD4 ITSN1-2 ITSN1-2 Y1Q_0005686 Y1Q_0005686 TOR1A TOR1A TOR1B TOR1B Y1Q_0005689 Y1Q_0005689 GPR21 GPR21 RPS27A RPS27A CLHC1 CLHC1 NECAP2 NECAP2 CLTCL1 CLTCL1 COPS7B COPS7B LDLRAP1 LDLRAP1 SCARB2 SCARB2 PPP1R42 PPP1R42 COPS5 COPS5 PPP1R42L PPP1R42L STAM-2 STAM-2 Y1Q_0019087 Y1Q_0019087 BMP2K-2 BMP2K-2 Y1Q_0020670 Y1Q_0020670 NETO2 NETO2 SLC18A3 SLC18A3 VAMP2-2 VAMP2-2 SNAP91 SNAP91 GRK2 GRK2 ZFYVE19 ZFYVE19 ZFYVE1 ZFYVE1 HGS HGS IL7R-1 IL7R-1 LMBRD2 LMBRD2 AVP AVP ARRB2 ARRB2 CLTB-1 CLTB-1 SH3GL1 SH3GL1 REPS2 REPS2 SH3KBP1 SH3KBP1 AP2A2 AP2A2 Y1Q_0008175 Y1Q_0008175 COPS3 COPS3 EPN2 EPN2 GRB2 GRB2 LRP13 LRP13 AP2A2-2 AP2A2-2 BTC BTC EREG EREG EPGN EPGN SYT11 SYT11 CLTC CLTC SYT2 SYT2 AGFG1 AGFG1 CLTA CLTA Y1Q_0008015 Y1Q_0008015 NETO1 NETO1 ENTHD1-1 ENTHD1-1 FCHO1 FCHO1 VTG1 VTG1 Y1Q_0020858 Y1Q_0020858 CHRM4 CHRM4 SGIP1 SGIP1 SYT5-2 SYT5-2 ARR3 ARR3 FZD4 FZD4 PICALM-2 PICALM-2 EPN1 EPN1 PICALM PICALM ARR3-2 ARR3-2 HBEGF-1 HBEGF-1 SCARB1 SCARB1 ADRBK1 ADRBK1 VAMP4 VAMP4 VAMP8 VAMP8 KXD1 KXD1 STON1 STON1 EPS15 EPS15 Y1Q_0004499 Y1Q_0004499 Y1Q_0022375 Y1Q_0022375 SH3GL2 SH3GL2 COPS4 COPS4 AP2S1 AP2S1 TGFA TGFA BMP2K BMP2K Y1Q_0016694 Y1Q_0016694 Y1Q_0016695 Y1Q_0016695 M6PR M6PR NECAP1 NECAP1 Y1Q_0016697 Y1Q_0016697 Y1Q_0023041 Y1Q_0023041 VAMP7 VAMP7 AP2M1 AP2M1 CFTR CFTR CD3D CD3D KIAA0319L KIAA0319L SYT5 SYT5 FCHO2 FCHO2 COPS6 COPS6 Y1Q_0004099 Y1Q_0004099 ITSN1 ITSN1 APOB APOB AGFG2 AGFG2 CD2AP CD2AP CLPB CLPB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYT4Synaptotagmin-4. (425 aa)
TGOLN2Trans-Golgi network integral membrane protein 2. (267 aa)
Y1Q_0011539Low-density lipoprotein receptor-related protein 1-like. (1403 aa)
LRP6Low-density lipoprotein receptor-related protein 6 isoform B. (3130 aa)
STAMSignal transducing adapter molecule 1 isoform C. (582 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2470 aa)
REPS1RalBP1-associated Eps domain-containing protein 1 isoform A. (802 aa)
Y1Q_0024416Uncharacterized protein. (127 aa)
EPS15-2Uncharacterized protein. (915 aa)
STON2Stonin-2 isoform B; Belongs to the Stoned B family. (910 aa)
Y1Q_0006860Uncharacterized protein. (1364 aa)
VAMP2-1Vesicle-associated membrane protein 2. (166 aa)
GPS1COP9 signalosome complex subunit 1 isoform A. (465 aa)
UBQLN4Ubiquilin-4 isoform B. (581 aa)
NEDD8NEDD8. (79 aa)
MCTP1Multiple C2 and transmembrane domain-containing protein 1 isoform C. (1003 aa)
SH3GL3Endophilin-A3. (353 aa)
COPS2COP9 signalosome complex subunit 2 isoform B. (436 aa)
UBL7Ubiquitin-like protein 7. (519 aa)
LRP4Uncharacterized protein. (1838 aa)
SYT9-2Uncharacterized protein. (524 aa)
SYT8Synaptotagmin-8. (396 aa)
COPS7ACOP9 signalosome complex subunit 7a. (291 aa)
CD4T-cell surface glycoprotein CD4. (551 aa)
ITSN1-2Uncharacterized protein. (492 aa)
Y1Q_0005686Torsin-1A-like. (335 aa)
TOR1ATorsin. (323 aa)
TOR1BTorsin. (332 aa)
Y1Q_0005689Torsin. (334 aa)
GPR21Putative G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (587 aa)
NECAP2Adaptin ear-binding coat-associated protein 2. (263 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1672 aa)
COPS7BCOP9 signalosome complex subunit 7b. (293 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (302 aa)
SCARB2Lysosome membrane protein 2; Belongs to the CD36 family. (482 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (171 aa)
COPS5COP9 signalosome complex subunit 5. (149 aa)
PPP1R42LProtein phosphatase 1 regulatory subunit 42. (308 aa)
STAM-2Uncharacterized protein. (335 aa)
Y1Q_0019087Uncharacterized protein. (152 aa)
BMP2K-2Protein kinase domain-containing protein. (1055 aa)
Y1Q_0020670COP9 signalosome complex subunit 4-like. (104 aa)
NETO2Neuropilin and tolloid-like protein 2 isoform C. (550 aa)
SLC18A3Vesicular acetylcholine transporter. (510 aa)
VAMP2-2Vesicle-associated membrane protein 2. (122 aa)
SNAP91Clathrin coat assembly protein AP180 isoform A. (857 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
ZFYVE19Abscission/NoCut checkpoint regulator. (429 aa)
ZFYVE1Zinc finger FYVE domain-containing protein 1. (697 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate isoform B. (853 aa)
IL7R-1Interleukin-7 receptor subunit alpha isoform A. (431 aa)
LMBRD2LMBR1 domain-containing protein 2. (690 aa)
AVPVasotocin-neurophysin VT; Belongs to the vasopressin/oxytocin family. (161 aa)
ARRB2Arrestin_C domain-containing protein. (407 aa)
CLTB-1Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
SH3GL1Uncharacterized protein. (367 aa)
REPS2RalBP1-associated Eps domain-containing protein 2 isoform C. (683 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform A. (661 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (959 aa)
Y1Q_0008175Vitellogenin-like. (3859 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
EPN2Epsin-2. (583 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LRP13Low-density lipoprotein receptor-related protein 2. (2157 aa)
AP2A2-2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (911 aa)
BTCProbetacellulin. (170 aa)
EREGProepiregulin. (159 aa)
EPGNEpigen isoform B. (150 aa)
SYT11Synaptotagmin-11. (429 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1744 aa)
SYT2Synaptotagmin-2. (398 aa)
AGFG1Arf-GAP domain and FG repeat-containing protein 1 isoform A. (564 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
Y1Q_0008015Uncharacterized protein. (1066 aa)
NETO1Neuropilin and tolloid-like protein 1. (533 aa)
ENTHD1-1ENTH domain-containing protein 1 isoform C. (602 aa)
FCHO1F-BAR domain only protein 1. (919 aa)
VTG1Vitellogenin-1. (1746 aa)
Y1Q_0020858Vitellogenin-1-like. (2014 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (469 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1 isoform D. (861 aa)
SYT5-2Uncharacterized protein. (451 aa)
ARR3Arrestin-C isoform B. (428 aa)
FZD4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (465 aa)
PICALM-2ENTH domain-containing protein. (609 aa)
EPN1Epsin-1. (639 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform A. (669 aa)
ARR3-2Arrestin_C domain-containing protein. (394 aa)
HBEGF-1Proheparin-binding EGF-like growth factor isoform B. (205 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (695 aa)
VAMP4Vesicle-associated membrane protein 4. (165 aa)
VAMP8Vesicle-associated membrane protein 8. (94 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
STON1Stonin-1; Belongs to the Stoned B family. (448 aa)
EPS15Epidermal growth factor receptor substrate 15 isoform A. (1267 aa)
Y1Q_0004499Uncharacterized protein. (568 aa)
Y1Q_0022375Vesicle-associated membrane protein 8-like. (102 aa)
SH3GL2Endophilin-A1 isoform A. (352 aa)
COPS4COP9 signalosome complex subunit 4. (190 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
TGFAProtransforming growth factor alpha. (159 aa)
BMP2KBMP-2-inducible protein kinase isoform B. (1003 aa)
Y1Q_0016694Ubiquilin-1-like. (588 aa)
Y1Q_0016695Ubiquitin-like domain-containing protein. (515 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (308 aa)
NECAP1Adaptin ear-binding coat-associated protein 1. (256 aa)
Y1Q_0016697Ubiquilin-1-like. (432 aa)
Y1Q_0023041MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (350 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
AP2M1AP-2 complex subunit mu isoform B; Belongs to the peptidase M10A family. (835 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1500 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (198 aa)
KIAA0319LDyslexia-associated KIAA0319-like protein-like protein. (951 aa)
SYT5Synaptotagmin-5 isoform B. (426 aa)
FCHO2F-BAR domain only protein 2 isoform B. (876 aa)
COPS6COP9 signalosome complex subunit 6. (297 aa)
Y1Q_0004099Uncharacterized protein. (720 aa)
ITSN1Intersectin-1. (1767 aa)
APOBApolipoprotein B-100. (4482 aa)
AGFG2Arf-GAP domain and FG repeat-containing protein 2 isoform A. (419 aa)
CD2APCD2-associated protein isoform C. (658 aa)
CLPBCaseinolytic peptidase B protein-like protein. (610 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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