STRINGSTRING
PSMD12 PSMD12 TCF7L1 TCF7L1 PSMD14 PSMD14 PSMA3 PSMA3 PSMB1 PSMB1 CTGF CTGF PSMB4 PSMB4 PSMD4 PSMD4 SNW1 SNW1 Y1Q_0010680 Y1Q_0010680 TCF7 TCF7 HYKK HYKK PSMC3 PSMC3 CCND1 CCND1 Y1Q_0000641 Y1Q_0000641 PSMA1 PSMA1 NOTCH1 NOTCH1 PSMD5-1 PSMD5-1 PSMB7 PSMB7 FNDC3A FNDC3A RPS27A RPS27A FNDC3A-2 FNDC3A-2 LEF1 LEF1 PSMD6 PSMD6 PSMB8 PSMB8 PSMB9 PSMB9 CBFB CBFB Y1Q_0003734 Y1Q_0003734 KAT2B KAT2B TP53 TP53 Y1Q_0009747 Y1Q_0009747 PSMD1 PSMD1 Y1Q_0005128 Y1Q_0005128 SMURF1 SMURF1 SMURF2 SMURF2 Y1Q_0019034 Y1Q_0019034 MAMLD1 MAMLD1 TEAD3 TEAD3 Y1Q_0014891 Y1Q_0014891 PSMA5 PSMA5 PSMC5 PSMC5 MAML3 MAML3 MAML3-2 MAML3-2 PSMC4 PSMC4 CREBBPA CREBBPA CREBBP CREBBP Y1Q_0024039 Y1Q_0024039 NINJ2 NINJ2 PSMA6 PSMA6 PSME2 PSME2 PSME1 PSME1 PSMD10 PSMD10 Y1Q_0015649 Y1Q_0015649 ZFHX4 ZFHX4 PSMD7 PSMD7 ZFHX2 ZFHX2 PSMC2 PSMC2 PSMB5 PSMB5 Y1Q_0023903 Y1Q_0023903 PSMD9-1 PSMD9-1 HES1 HES1 PSMB6 PSMB6 KXD1 KXD1 TCF7L2 TCF7L2 PSMD13 PSMD13 RBPJL RBPJL TGFB1 TGFB1 MAML2 MAML2 PSMF1 PSMF1 CTNNB1 CTNNB1 PSMD3 PSMD3 PSMB3 PSMB3 TEAD1 TEAD1 PSMD2 PSMD2 PSMC1 PSMC1 RBPJ RBPJ PSMD11 PSMD11 DHX58 DHX58 PSMC6 PSMC6 MDM2 MDM2 PSMB2 PSMB2 SMAD4 SMAD4 PSMD8 PSMD8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD1226S proteasome non-ATPase regulatory subunit 12. (441 aa)
TCF7L1Transcription factor 7-like 1 isoform D. (567 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (460 aa)
PSMA3Proteasome subunit alpha type. (256 aa)
PSMB1Proteasome subunit beta. (240 aa)
CTGFConnective tissue growth factor. (341 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
SNW1SNW domain-containing protein 1. (536 aa)
Y1Q_0010680Uncharacterized protein. (176 aa)
TCF7Transcription factor 7 isoform A. (452 aa)
HYKKProteasome endopeptidase complex. (600 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
Y1Q_0000641TEA domain-containing protein. (455 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
NOTCH1Uncharacterized protein. (2308 aa)
PSMD5-126S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
PSMB7Proteasome subunit beta. (274 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1011 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
FNDC3A-2Uncharacterized protein. (1195 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform B. (391 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (348 aa)
PSMB8Proteasome subunit beta. (282 aa)
PSMB9Proteasome subunit beta. (216 aa)
CBFBCore-binding factor subunit beta. (187 aa)
Y1Q_0003734Uncharacterized protein. (2484 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (783 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
Y1Q_0009747Mothers against decapentaplegic homolog. (517 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
Y1Q_0005128Proteasome subunit beta. (277 aa)
SMURF1E3 ubiquitin-protein ligase. (732 aa)
SMURF2E3 ubiquitin-protein ligase. (786 aa)
Y1Q_0019034RPN1_C domain-containing protein. (356 aa)
MAMLD1Mastermind-like domain-containing protein 1. (914 aa)
TEAD3Transcriptional enhancer factor TEF-5. (322 aa)
Y1Q_0014891TEA domain-containing protein. (161 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
MAML3Mastermind-like protein 3 isoform B. (652 aa)
MAML3-2MamL-1 domain-containing protein. (164 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
CREBBPACREB-binding protein isoform A. (1756 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
NINJ2Ninjurin-2. (154 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
PSME1Proteasome activator complex subunit 1. (150 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
Y1Q_0015649Uncharacterized protein. (1191 aa)
ZFHX4Zinc finger homeobox protein 4 isoform B. (3538 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
ZFHX2Zinc finger homeobox protein 2 isoform A. (1500 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB5Proteasome subunit beta type-5. (211 aa)
Y1Q_0023903C2H2-type domain-containing protein. (475 aa)
PSMD9-126S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
HES1Transcription factor HES-1. (262 aa)
PSMB6Proteasome subunit beta. (227 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
TCF7L2Transcription factor 7-like 2 isoform A. (411 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
RBPJLRecombining binding protein suppressor of hairless-like protein isoform A. (494 aa)
TGFB1TGF_BETA_2 domain-containing protein. (242 aa)
MAML2Mastermind-like protein 2. (451 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
CTNNB1Catenin beta-1 isoform B. (783 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (521 aa)
PSMB3Proteasome subunit beta. (205 aa)
TEAD1Transcriptional enhancer factor TEF-1; Belongs to the TUB family. (911 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2. (513 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
RBPJRecombining binding protein suppressor of hairless isoform B. (498 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (518 aa)
DHX58Putative ATP-dependent RNA helicase DHX58 isoform E; Belongs to the small heat shock protein (HSP20) family. (1743 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (494 aa)
PSMB2Proteasome subunit beta. (201 aa)
SMAD4Mothers against decapentaplegic homolog. (559 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (257 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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