21 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Y1Q_0017424	Uncharacterized protein. (235 aa)
	SOS1-2	Son of sevenless-like protein. (1379 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SYK-2	Tyrosine-protein kinase. (608 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta isoform A. (1187 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	AKT3-2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	Y1Q_0018542	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (627 aa)
	NRAS	GTPase NRas. (189 aa)
	AKT2	Non-specific serine/threonine protein kinase. (270 aa)
	FLT3	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1110 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	GAB2	GRB2-associated-binding protein 2. (677 aa)
	SOCS6	Suppressor of cytokine signaling 6. (533 aa)
	GRAP2	GRB2-related adapter protein 2. (382 aa)
	KRAS-2	GTPase KRas. (219 aa)
	KRAS-1	GTPase KRas. (215 aa)
	SH2B3	SH2B adapter protein 3. (600 aa)
	SLA2	Src-like-adapter 2. (243 aa)
	Y1Q_0006325	Uncharacterized protein. (188 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	AKT3	A0A151MPY5	A0A151M239	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	AKT3-2	A0A151MPY5	A0A151MH49	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.902
AKT2	PIK3CB	A0A151MPY5	A0A151M6C3	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.948
AKT2	Y1Q_0017424	A0A151MPY5	A0A151PCN9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.899
AKT2	Y1Q_0018542	A0A151MPY5	A0A151MP29	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.509
AKT3	AKT2	A0A151M239	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3	AKT3-2	A0A151M239	A0A151MH49	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT3	PIK3CB	A0A151M239	A0A151M6C3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.963
AKT3	Y1Q_0018542	A0A151M239	A0A151MP29	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.509
AKT3-2	AKT2	A0A151MH49	A0A151MPY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.902
AKT3-2	AKT3	A0A151MH49	A0A151M239	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT3-2	PIK3CB	A0A151MH49	A0A151M6C3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.948
AKT3-2	Y1Q_0018542	A0A151MH49	A0A151MP29	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.509
FLT3	GRAP2	A0A151MSD7	A0A151NIE3	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	GRB2-related adapter protein 2.	0.540
FLT3	GRB2	A0A151MSD7	A0A151N2T8	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Growth factor receptor-bound protein 2.	0.920
FLT3	KRAS-1	A0A151MSD7	A0A151NK14	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	GTPase KRas.	0.416
FLT3	KRAS-2	A0A151MSD7	A0A151NIW9	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	GTPase KRas.	0.416
FLT3	NRAS	A0A151MSD7	A0A151PHE9	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	GTPase NRas.	0.416
FLT3	PIK3CB	A0A151MSD7	A0A151M6C3	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.636
FLT3	PTPRJ	A0A151MSD7	A0A151MCB1	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Receptor-type tyrosine-protein phosphatase eta isoform A.	0.697