STRINGSTRING
Y1Q_0008055 Y1Q_0008055 LAMTOR1 LAMTOR1 ATG7 ATG7 ATG12 ATG12 ATG10 ATG10 CETN3 CETN3 CHMP4C CHMP4C CFTR CFTR PRKAG2 PRKAG2 CRYGN CRYGN RHEB RHEB GFAP GFAP NBR1 NBR1 BECN1 BECN1 TOMM40 TOMM40 CHMP3 CHMP3 DYNC1H1 DYNC1H1 Y1Q_0004773 Y1Q_0004773 FUNDC2 FUNDC2 RRAGB RRAGB ATG5 ATG5 TUBE1 TUBE1 ATG4B ATG4B RB1CC1 RB1CC1 DYNC1I1 DYNC1I1 DYNC1LI1 DYNC1LI1 Y1Q_0020755 Y1Q_0020755 GABARAPL1 GABARAPL1 Y1Q_0021221 Y1Q_0021221 CSNK2A2 CSNK2A2 TUBB6 TUBB6 RRAGD-2 RRAGD-2 Y1Q_0010427 Y1Q_0010427 PIK3C3 PIK3C3 PRKAA1-2 PRKAA1-2 SLC38A9 SLC38A9 MTERF3 MTERF3 Y1Q_0023921 Y1Q_0023921 TUBB TUBB TXNDC11 TXNDC11 WIPI2 WIPI2 TSC2 TSC2 WIPI1 WIPI1 CUNH17orf75 CUNH17orf75 MTOR MTOR MFN2-2 MFN2-2 PRKAB1 PRKAB1 DYNLL1 DYNLL1 MTMR3 MTMR3 DYNLL2 DYNLL2 Y1Q_0012818 Y1Q_0012818 TUBA1C TUBA1C DYNC1LI2 DYNC1LI2 LAMTOR5 LAMTOR5 ZCCHC3 ZCCHC3 GABARAP GABARAP TUBAL3 TUBAL3 ULK2 ULK2 Y1Q_0024551 Y1Q_0024551 TM9SF1 TM9SF1 MAP1LC3B MAP1LC3B TUBB6-2 TUBB6-2 Y1Q_0008056 Y1Q_0008056 RRAGD RRAGD TOMM22 TOMM22 Y1Q_0024323 Y1Q_0024323 Y1Q_0024324 Y1Q_0024324 ATG4C ATG4C Y1Q_0008958 Y1Q_0008958 TUBB4A TUBB4A ATG16L2 ATG16L2 Y1Q_0011128 Y1Q_0011128 LAMTOR3 LAMTOR3 ATG4A ATG4A Y1Q_0015649 Y1Q_0015649 ARHGEF3 ARHGEF3 Y1Q_0023492 Y1Q_0023492 Y1Q_0023503 Y1Q_0023503 ATG9A ATG9A CSNK2B CSNK2B Y1Q_0020178 Y1Q_0020178 Y1Q_0020177 Y1Q_0020177 FUNDC1 FUNDC1 ULK1A ULK1A USP30 USP30 SCARB1 SCARB1 PRKAB2-1 PRKAB2-1 Y1Q_0004461 Y1Q_0004461 ATG101 ATG101 Y1Q_0018793 Y1Q_0018793 ATG16L1 ATG16L1 Y1Q_0006458 Y1Q_0006458 KXD1 KXD1 WDR45B WDR45B Y1Q_0013352 Y1Q_0013352 MLST8 MLST8 TUBB3 TUBB3 CSNK2A1 CSNK2A1 CUNH6orf106 CUNH6orf106 LAMTOR2 LAMTOR2 RHEBL1 RHEBL1 UBE2V1 UBE2V1 MAP1LC3A MAP1LC3A TUBB1 TUBB1 Y1Q_0016784 Y1Q_0016784 GABARAPL2 GABARAPL2 PLIN2 PLIN2 PIK3R4 PIK3R4 RPTOR RPTOR CHMP6 CHMP6 CHMP2A CHMP2A Y1Q_0016077 Y1Q_0016077 MTMR14 MTMR14 CHMP7-1 CHMP7-1 CHMP4B CHMP4B PRKAG1 PRKAG1 Y1Q_0002398 Y1Q_0002398 IFT88 IFT88 ATM ATM TUBA8B TUBA8B PARK7 PARK7 UBE2N UBE2N ATG4D ATG4D DYNC1I2 DYNC1I2 ATG14 ATG14 Y1Q_0009137 Y1Q_0009137 PARK2 PARK2 PARK2L PARK2L TOMM20 TOMM20 UVRAG UVRAG PRKAA1 PRKAA1 TOMM40L TOMM40L PEX5L PEX5L MFN2 MFN2 Y1Q_0010680 Y1Q_0010680 VDAC1 VDAC1 WDR45 WDR45 SQSTM1 SQSTM1 CHMP4A CHMP4A MDP1 MDP1 AMBRA1 AMBRA1 LAMTOR4 LAMTOR4 PEX5 PEX5 ATG3 ATG3 TOMM70A TOMM70A ARL13B ARL13B CHMP2B CHMP2B TSC1 TSC1 FNDC3A FNDC3A RPS27A RPS27A MAP1LC3C MAP1LC3C FNDC3A-2 FNDC3A-2 PINK1 PINK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Y1Q_0008055Tubulin domain-containing protein. (158 aa)
LAMTOR1Ragulator complex protein LAMTOR1. (161 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (815 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (150 aa)
ATG10Ubiquitin-like-conjugating enzyme ATG10. (263 aa)
CETN3Centrin-3. (167 aa)
CHMP4CCharged multivesicular body protein 4c. (221 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1500 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2. (567 aa)
CRYGNGamma-crystallin N; Belongs to the beta/gamma-crystallin family. (177 aa)
RHEBGTP-binding protein Rheb. (184 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (447 aa)
NBR1Next to BRCA1 1 protein isoform A. (1075 aa)
BECN1Beclin-1. (467 aa)
TOMM40Mitochondrial import receptor subunit TOM40-like protein. (351 aa)
CHMP3Charged multivesicular body protein 3. (220 aa)
DYNC1H1Uncharacterized protein. (4633 aa)
Y1Q_0004773Tubulin_C domain-containing protein. (148 aa)
FUNDC2FUN14 domain-containing protein 2. (208 aa)
RRAGBRas-related GTP-binding protein A. (327 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TUBE1Tubulin epsilon chain; Belongs to the tubulin family. (475 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (391 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform A. (1595 aa)
DYNC1I1WD_REPEATS_REGION domain-containing protein. (675 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (532 aa)
Y1Q_00207555'-AMP-activated protein kinase subunit gamma-3-like. (99 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
Y1Q_0021221TMEM189_B_dmain domain-containing protein. (76 aa)
CSNK2A2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (345 aa)
RRAGD-2Uncharacterized protein. (410 aa)
Y1Q_0010427Uncharacterized protein. (275 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
PRKAA1-2Non-specific serine/threonine protein kinase. (547 aa)
SLC38A9Sodium-coupled neutral amino acid transporter 9. (561 aa)
MTERF3Transcription termination factor 3, mitochondrial. (336 aa)
Y1Q_0023921Autophagy-related protein 16-like. (250 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
TXNDC11Thioredoxin domain-containing protein 11. (901 aa)
WIPI2WD repeat domain phosphoinositide-interacting protein 2 isoform B. (436 aa)
TSC2Tuberin isoform D. (1829 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1. (443 aa)
CUNH17orf75Protein Njmu-R1. (388 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
MFN2-2Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (302 aa)
DYNLL1Dynein light chain. (123 aa)
MTMR3Uncharacterized protein. (1166 aa)
DYNLL2Dynein light chain. (77 aa)
Y1Q_0012818Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (341 aa)
TUBA1CTubulin alpha chain. (127 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (489 aa)
LAMTOR5Ragulator complex protein LAMTOR5. (91 aa)
ZCCHC3Zinc finger CCHC domain-containing protein 3. (302 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ULK2Serine/threonine-protein kinase ULK2. (1048 aa)
Y1Q_0024551Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
TM9SF1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (683 aa)
MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B. (125 aa)
TUBB6-2Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
Y1Q_0008056Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (397 aa)
RRAGDRas-related GTP-binding protein D. (333 aa)
TOMM22Mitochondrial import receptor subunit TOM22-like protein. (103 aa)
Y1Q_0024323Tubulin alpha-8 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (229 aa)
Y1Q_0024324Tubulin alpha-8 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (222 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (437 aa)
Y1Q_0008958Methyltransf_11 domain-containing protein. (301 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ATG16L2Autophagy-related protein 16-2 isoform A. (406 aa)
Y1Q_0011128WD_REPEATS_REGION domain-containing protein. (105 aa)
LAMTOR3Ragulator complex protein LAMTOR3. (124 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (384 aa)
Y1Q_0015649Uncharacterized protein. (1191 aa)
ARHGEF3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (223 aa)
Y1Q_0023492Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (206 aa)
Y1Q_0023503Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (193 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (802 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa)
Y1Q_0020178Tubulin alpha chain-like. (151 aa)
Y1Q_0020177Uncharacterized protein. (70 aa)
FUNDC1FUN14 domain-containing protein 1. (156 aa)
ULK1AUnc-51 like autophagy activating kinase 1a isoform A. (1048 aa)
USP30Ubiquitin carboxyl-terminal hydrolase. (481 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
PRKAB2-15'-AMP-activated protein kinase subunit beta-2 isoform B. (274 aa)
Y1Q_0004461Uncharacterized protein. (333 aa)
ATG101Autophagy-related protein 101. (218 aa)
Y1Q_0018793Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (2196 aa)
ATG16L1Autophagy-related protein 16-1. (607 aa)
Y1Q_0006458Uncharacterized protein. (71 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
WDR45BWD repeat domain phosphoinositide-interacting protein 3. (344 aa)
Y1Q_0013352Microtubule-associated proteins 1A/1B light chain 3C-like. (131 aa)
MLST8Target of rapamycin complex subunit LST8. (403 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (444 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (435 aa)
CUNH6orf106N_BRCA1_IG domain-containing protein. (254 aa)
LAMTOR2Ragulator complex protein LAMTOR2. (173 aa)
RHEBL1GTPase RhebL1. (184 aa)
UBE2V1UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa)
MAP1LC3AUncharacterized protein. (93 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (467 aa)
Y1Q_00167845'-AMP-activated protein kinase subunit gamma-3-like. (129 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
PLIN2Perilipin; Belongs to the perilipin family. (516 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1397 aa)
RPTORRegulatory-associated protein of mTOR isoform A. (1352 aa)
CHMP6Charged multivesicular body protein 6. (187 aa)
CHMP2ACharged multivesicular body protein 2a. (220 aa)
Y1Q_0016077Uncharacterized protein. (68 aa)
MTMR14Myotubularin-related protein 14. (354 aa)
CHMP7-1Charged multivesicular body protein 7 isoform A. (398 aa)
CHMP4BCharged multivesicular body protein 4b. (211 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform A. (330 aa)
Y1Q_0002398Uncharacterized protein. (72 aa)
IFT88Intraflagellar transport 88-like protein. (817 aa)
ATMNon-specific serine/threonine protein kinase. (3063 aa)
TUBA8BTubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (295 aa)
PARK7Protein deglycase DJ-1. (159 aa)
UBE2NUbiquitin-conjugating enzyme E2 N. (112 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (446 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2 isoform C. (726 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (497 aa)
Y1Q_0009137Ubiquitin-like domain-containing protein. (87 aa)
PARK2E3 ubiquitin-protein ligase parkin isoform A. (280 aa)
PARK2LRBR-type E3 ubiquitin transferase. (180 aa)
TOMM20Mitochondrial import receptor subunit TOM20-like protein. (146 aa)
UVRAGUV radiation resistance-associated protein. (672 aa)
PRKAA1Non-specific serine/threonine protein kinase. (527 aa)
TOMM40LMitochondrial import receptor subunit TOM40B. (289 aa)
PEX5LPEX5-related protein isoform C. (608 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (970 aa)
Y1Q_0010680Uncharacterized protein. (176 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (581 aa)
WDR45WD repeat domain phosphoinositide-interacting protein 4. (621 aa)
SQSTM1Sequestosome-1. (457 aa)
CHMP4ACharged multivesicular body protein 4a. (218 aa)
MDP1Magnesium-dependent phosphatase 1. (160 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform A. (1224 aa)
LAMTOR4Ragulator complex protein LAMTOR4. (99 aa)
PEX5Peroxisomal biogenesis factor 5 isoform A. (646 aa)
ATG3Autophagy-related protein 3. (311 aa)
TOMM70AMitochondrial import receptor subunit TOM70. (501 aa)
ARL13BADP-ribosylation factor-like protein 13B isoform A. (432 aa)
CHMP2BCharged multivesicular body protein 2b. (214 aa)
TSC1Hamartin isoform B. (1115 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1011 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
MAP1LC3CMicrotubule-associated proteins 1A/1B light chain 3C. (143 aa)
FNDC3A-2Uncharacterized protein. (1195 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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