80 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Y1Q_0004461	Uncharacterized protein. (333 aa)
	DYNC1I2	Cytoplasmic dynein 1 intermediate chain 2 isoform C. (726 aa)
	Y1Q_0009137	Ubiquitin-like domain-containing protein. (87 aa)
	PARK2	E3 ubiquitin-protein ligase parkin isoform A. (280 aa)
	PARK2L	RBR-type E3 ubiquitin transferase. (180 aa)
	TOMM20	Mitochondrial import receptor subunit TOM20-like protein. (146 aa)
	TOMM40L	Mitochondrial import receptor subunit TOM40B. (289 aa)
	PEX5L	PEX5-related protein isoform C. (608 aa)
	MFN2	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (970 aa)
	FNDC3A-2	Uncharacterized protein. (1195 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	TUBE1	Tubulin epsilon chain; Belongs to the tubulin family. (475 aa)
	DYNC1I1	WD_REPEATS_REGION domain-containing protein. (675 aa)
	DYNC1LI1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (532 aa)
	Y1Q_0021221	TMEM189_B_dmain domain-containing protein. (76 aa)
	CSNK2A2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
	TUBB6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (345 aa)
	Y1Q_0010427	Uncharacterized protein. (275 aa)
	MTERF3	Transcription termination factor 3, mitochondrial. (336 aa)
	TUBB	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	MFN2-2	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
	DYNLL1	Dynein light chain. (123 aa)
	DYNLL2	Dynein light chain. (77 aa)
	Y1Q_0012818	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (341 aa)
	TUBA1C	Tubulin alpha chain. (127 aa)
	DYNC1LI2	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (489 aa)
	ZCCHC3	Zinc finger CCHC domain-containing protein 3. (302 aa)
	TUBAL3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	ULK2	Serine/threonine-protein kinase ULK2. (1048 aa)
	Y1Q_0024551	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	MAP1LC3B	Microtubule-associated proteins 1A/1B light chain 3B. (125 aa)
	TUBB6-2	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	Y1Q_0008056	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (397 aa)
	Y1Q_0008055	Tubulin domain-containing protein. (158 aa)
	TOMM22	Mitochondrial import receptor subunit TOM22-like protein. (103 aa)
	Y1Q_0024323	Tubulin alpha-8 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (229 aa)
	Y1Q_0024324	Tubulin alpha-8 chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (222 aa)
	Y1Q_0008958	Methyltransf_11 domain-containing protein. (301 aa)
	TUBB4A	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	Y1Q_0015649	Uncharacterized protein. (1191 aa)
	ARHGEF3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (223 aa)
	Y1Q_0023492	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (206 aa)
	Y1Q_0023503	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (193 aa)
	CSNK2B	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa)
	Y1Q_0020178	Tubulin alpha chain-like. (151 aa)
	Y1Q_0020177	Uncharacterized protein. (70 aa)
	FUNDC1	FUN14 domain-containing protein 1. (156 aa)
	ULK1A	Unc-51 like autophagy activating kinase 1a isoform A. (1048 aa)
	USP30	Ubiquitin carboxyl-terminal hydrolase. (481 aa)
	SCARB1	Scavenger receptor class B member 1 isoform A. (959 aa)
	KXD1	KxDL motif-containing protein 1. (293 aa)
	TUBB3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (444 aa)
	CSNK2A1	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (435 aa)
	CUNH6orf106	N_BRCA1_IG domain-containing protein. (254 aa)
	Y1Q_0010680	Uncharacterized protein. (176 aa)
	VDAC1	Voltage-dependent anion-selective channel protein 1. (581 aa)
	SQSTM1	Sequestosome-1. (457 aa)
	PEX5	Peroxisomal biogenesis factor 5 isoform A. (646 aa)
	TOMM70A	Mitochondrial import receptor subunit TOM70. (501 aa)
	ARL13B	ADP-ribosylation factor-like protein 13B isoform A. (432 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1011 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (150 aa)
	CETN3	Centrin-3. (167 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1500 aa)
	NBR1	Next to BRCA1 1 protein isoform A. (1075 aa)
	TOMM40	Mitochondrial import receptor subunit TOM40-like protein. (351 aa)
	DYNC1H1	Uncharacterized protein. (4633 aa)
	UBE2V1	UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa)
	MAP1LC3A	Uncharacterized protein. (93 aa)
	TUBB1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (467 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (516 aa)
	IFT88	Intraflagellar transport 88-like protein. (817 aa)
	ATM	Non-specific serine/threonine protein kinase. (3063 aa)
	FUNDC2	FUN14 domain-containing protein 2. (208 aa)
	Y1Q_0004773	Tubulin_C domain-containing protein. (148 aa)
	TUBA8B	Tubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (295 aa)
	PARK7	Protein deglycase DJ-1. (159 aa)
	UBE2N	Ubiquitin-conjugating enzyme E2 N. (112 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF3	TUBA8B	A0A151NQ41	A0A151LY82	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.950
ARHGEF3	TUBB	A0A151NQ41	A0A151MZH9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.629
ARHGEF3	TUBB1	A0A151NQ41	A0A151P055	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.629
ARHGEF3	TUBB3	A0A151NQ41	A0A151NWW7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.697
ARHGEF3	TUBB4A	A0A151NQ41	A0A151NL66	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.633
ARHGEF3	TUBB6	A0A151NQ41	A0A151MTI8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.673
ARHGEF3	TUBB6-2	A0A151NQ41	A0A151NET7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.634
ARHGEF3	TUBE1	A0A151NQ41	A0A151MJU9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin epsilon chain; Belongs to the tubulin family.	0.582
ARHGEF3	Y1Q_0004773	A0A151NQ41	A0A151P8E3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin_C domain-containing protein.	0.947
ARHGEF3	Y1Q_0008055	A0A151NQ41	A0A151NFQ9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin domain-containing protein.	0.631
ARHGEF3	Y1Q_0008056	A0A151NQ41	A0A151NFG2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.635
ARL13B	CETN3	A0A151MDJ4	A0A151PI22	ADP-ribosylation factor-like protein 13B isoform A.	Centrin-3.	0.506
ARL13B	CFTR	A0A151MDJ4	A0A151PEP4	ADP-ribosylation factor-like protein 13B isoform A.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.476
ARL13B	DYNC1H1	A0A151MDJ4	A0A151P8J8	ADP-ribosylation factor-like protein 13B isoform A.	Uncharacterized protein.	0.525
ARL13B	DYNC1I1	A0A151MDJ4	A0A151MQ68	ADP-ribosylation factor-like protein 13B isoform A.	WD_REPEATS_REGION domain-containing protein.	0.485
ARL13B	DYNC1I2	A0A151MDJ4	A0A151M055	ADP-ribosylation factor-like protein 13B isoform A.	Cytoplasmic dynein 1 intermediate chain 2 isoform C.	0.485
ARL13B	DYNLL1	A0A151MDJ4	A0A151N501	ADP-ribosylation factor-like protein 13B isoform A.	Dynein light chain.	0.473
ARL13B	DYNLL2	A0A151MDJ4	A0A151N637	ADP-ribosylation factor-like protein 13B isoform A.	Dynein light chain.	0.473
ARL13B	IFT88	A0A151MDJ4	A0A151P754	ADP-ribosylation factor-like protein 13B isoform A.	Intraflagellar transport 88-like protein.	0.876
ARL13B	SQSTM1	A0A151MDJ4	A0A151M7D3	ADP-ribosylation factor-like protein 13B isoform A.	Sequestosome-1.	0.412