STRINGSTRING
NUDT2 NUDT2 PSMD14 PSMD14 NFE2L2 NFE2L2 Y1Q_0011460 Y1Q_0011460 COX6B2 COX6B2 PSMB7 PSMB7 PSMD5-1 PSMD5-1 SURF1 SURF1 BACH1 BACH1 SOD1 SOD1 GSK3B-2 GSK3B-2 PSMA1 PSMA1 CAT CAT PSMC3 PSMC3 COX16 COX16 SYNJ2BP-2 SYNJ2BP-2 HYKK HYKK Y1Q_0001537 Y1Q_0001537 SPATA5L1 SPATA5L1 NOX5 NOX5 Y1Q_0001262 Y1Q_0001262 CARM1 CARM1 SQSTM1 SQSTM1 TBL1XR1 TBL1XR1 PSMD4 PSMD4 PSMB4 PSMB4 GPX7 GPX7 PSMB1 PSMB1 CUNH1orf198 CUNH1orf198 SOD2 SOD2 AKT3 AKT3 HBG1 HBG1 PSMB2 PSMB2 FBXL17-1 FBXL17-1 Y1Q_0004147 Y1Q_0004147 PSMD8 PSMD8 PRDX2 PRDX2 GPX4 GPX4 Y1Q_0020518 Y1Q_0020518 CYBA CYBA BLVRA BLVRA Y1Q_0017512 Y1Q_0017512 Y1Q_0017513 Y1Q_0017513 NME8 NME8 PSMF1 PSMF1 CUL1 CUL1 LRPPRC LRPPRC COX7A2L COX7A2L PSMD3 PSMD3 MED1 MED1 MED1-2 MED1-2 PSMB3 PSMB3 NFE2L1 NFE2L1 NCOA6 NCOA6 PDIA2 PDIA2 HBZ HBZ HBAA HBAA PPARAB PPARAB SCO1 SCO1 PSMD2 PSMD2 PSMC1 PSMC1 FABP1 FABP1 SOD3 SOD3 PSMD11 PSMD11 Y1Q_0017424 Y1Q_0017424 PSMC6 PSMC6 ERO1B ERO1B SPATA5 SPATA5 TYMP TYMP Y1Q_0012759 Y1Q_0012759 PRDX1 PRDX1 Y1Q_0012758 Y1Q_0012758 Y1Q_0012756 Y1Q_0012756 PSMA7 PSMA7 NWD1 NWD1 PSMD13 PSMD13 COX8A COX8A SRXN1 SRXN1 SESN2 SESN2 PRDX3-1 PRDX3-1 FAM45A-1 FAM45A-1 KXD1 KXD1 CARM1-2 CARM1-2 VCP VCP PSMB6 PSMB6 TXNRD2 TXNRD2 PRDX6 PRDX6 SCARB1 SCARB1 PSMD9-1 PSMD9-1 Y1Q_0018673 Y1Q_0018673 UFD1L UFD1L PSMA3 PSMA3 PSMB5 PSMB5 PSMB11 PSMB11 PSMC2 PSMC2 PSMD7 PSMD7 COX5B COX5B COX7B COX7B PSMD10 PSMD10 PSME1 PSME1 PSME2 PSME2 PSMA6 PSMA6 KEAP1 KEAP1 ATF4-1 ATF4-1 TXNRD1 TXNRD1 NCF4 NCF4 Y1Q_0024039 Y1Q_0024039 HMOX1 HMOX1 RBX1 RBX1 ATF4-2 ATF4-2 CREBBP CREBBP HMOX2 HMOX2 CREBBPA CREBBPA DESI1 DESI1 PSMC4 PSMC4 SESN2L SESN2L TXN TXN Y1Q_0018516 Y1Q_0018516 NCOR1 NCOR1 CUL3 CUL3 PSMC5 PSMC5 PSMA5 PSMA5 Y1Q_0008616 Y1Q_0008616 Y1Q_0019034 Y1Q_0019034 CUNH19orf43 CUNH19orf43 COX18 COX18 COX6A1 COX6A1 MTFP1 MTFP1 KLHL17 KLHL17 SPPL3 SPPL3 GSR GSR COIL COIL COX11 COX11 PSMD12 PSMD12 MAFK MAFK COX19 COX19 GSK3B GSK3B TBL1X TBL1X HELZ2 HELZ2 Y1Q_0005128 Y1Q_0005128 PSMD1 PSMD1 P4HB P4HB PRDX5 PRDX5 COX6C COX6C GPX8 GPX8 SKP2 SKP2 NOX4 NOX4 KLHL18 KLHL18 GPX3 GPX3 COX7A2 COX7A2 BACH2 BACH2 GPX1 GPX1 COX14 COX14 NPVF NPVF Y1Q_0019264 Y1Q_0019264 NDUFA4 NDUFA4 AKT2 AKT2 TGS1-2 TGS1-2 TGS1 TGS1 CCS CCS GPX2 GPX2 BLVRB BLVRB PSMB9 PSMB9 PSMB8 PSMB8 BTRC BTRC PSMD6 PSMD6 UBXN7 UBXN7 TXNRD3 TXNRD3 MUL1 MUL1 HM13 HM13 COX20 COX20 AKT3-2 AKT3-2 DESI2 DESI2 RPS27A RPS27A PSME4 PSME4 TACO1 TACO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUDT2Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. (187 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (460 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2. (482 aa)
Y1Q_0011460Uncharacterized protein. (103 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (107 aa)
PSMB7Proteasome subunit beta. (274 aa)
PSMD5-126S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
SURF1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (308 aa)
BACH1Transcription regulator protein BACH1 isoform A. (665 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
GSK3B-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
COX16COX16 cytochrome c oxidase assembly-like protein. (101 aa)
SYNJ2BP-2Synaptojanin 2 binding protein. (196 aa)
HYKKProteasome endopeptidase complex. (600 aa)
Y1Q_0001537HDAC_interact domain-containing protein. (1175 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1. (763 aa)
NOX5NADPH oxidase 5. (531 aa)
Y1Q_0001262Uncharacterized protein. (321 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (458 aa)
SQSTM1Sequestosome-1. (457 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1. (513 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa)
PSMB1Proteasome subunit beta. (240 aa)
CUNH1orf198DUF4706 domain-containing protein. (332 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HBG1Hemoglobin subunit rho; Belongs to the globin family. (189 aa)
PSMB2Proteasome subunit beta. (201 aa)
FBXL17-1F-box/LRR-repeat protein 17 isoform A. (327 aa)
Y1Q_0004147Uncharacterized protein. (114 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (257 aa)
PRDX2Peroxiredoxin-2. (174 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
Y1Q_0020518Cytochrome c oxidase subunit 6A2, mitochondrial; Belongs to the cytochrome c oxidase subunit 6A family. (107 aa)
CYBACytochrome b-245 light chain. (171 aa)
BLVRABiliverdin reductase A. (458 aa)
Y1Q_0017512Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (345 aa)
Y1Q_0017513Mediator of RNA polymerase II transcription subunit 1-like. (204 aa)
NME8Thioredoxin domain-containing protein 3 isoform B. (615 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
LRPPRCLeucine-rich PPR motif-containing protein, mitochondrial isoform A. (1357 aa)
COX7A2LCytochrome c oxidase subunit VIIa polypeptide 2 like. (116 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (521 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1104 aa)
MED1-2Uncharacterized protein. (259 aa)
PSMB3Proteasome subunit beta. (205 aa)
NFE2L1Nuclear factor erythroid 2-related factor 1. (876 aa)
NCOA6Nuclear receptor coactivator 6. (935 aa)
PDIA2Protein disulfide-isomerase. (539 aa)
HBZHemoglobin subunit pi; Belongs to the globin family. (142 aa)
HBAAHemoglobin subunit alpha-A; Belongs to the globin family. (142 aa)
PPARABPeroxisome proliferator-activated receptor alpha. (438 aa)
SCO1SCO1-like protein, mitochondrial. (256 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2. (513 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
FABP1Fatty acid-binding protein, liver. (127 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (244 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (518 aa)
Y1Q_0017424Uncharacterized protein. (235 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
ERO1BERO1-like protein beta. (446 aa)
SPATA5Spermatogenesis-associated protein 5. (871 aa)
TYMPThymidine phosphorylase. (275 aa)
Y1Q_0012759Hemoglobin subunit beta-like; Belongs to the globin family. (140 aa)
PRDX1Peroxiredoxin-1. (206 aa)
Y1Q_0012758Hemoglobin subunit beta; Belongs to the globin family. (130 aa)
Y1Q_0012756GLOBIN domain-containing protein; Belongs to the globin family. (140 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
NWD1Tetraspanin. (2546 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
COX8ACytochrome c oxidase subunit 8A, mitochondrial. (70 aa)
SRXN1Sulfiredoxin. (118 aa)
SESN2Sestrin-3-like. (447 aa)
PRDX3-1Thioredoxin-dependent peroxide reductase, mitochondrial isoform A. (385 aa)
FAM45A-1Protein FAM45A isoform B. (327 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
CARM1-2CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (548 aa)
VCPUncharacterized protein; Belongs to the AAA ATPase family. (880 aa)
PSMB6Proteasome subunit beta. (227 aa)
TXNRD2Thioredoxin reductase 2, mitochondrial. (506 aa)
PRDX6Peroxiredoxin-6. (224 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
PSMD9-126S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
Y1Q_0018673Uncharacterized protein. (2454 aa)
UFD1LUbiquitin fusion degradation 1-like protein. (307 aa)
PSMA3Proteasome subunit alpha type. (256 aa)
PSMB5Proteasome subunit beta type-5. (211 aa)
PSMB11Proteasome subunit beta. (261 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
COX5BCytochrome c oxidase subunit 5B, mitochondrial. (130 aa)
COX7BCytochrome c oxidase subunit 7B, mitochondrial. (79 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
PSME1Proteasome activator complex subunit 1. (150 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
KEAP1Kelch-like ECH-associated protein 1. (480 aa)
ATF4-1Cyclic AMP-dependent transcription factor ATF-4. (117 aa)
TXNRD1Glutaredoxin domain-containing protein. (651 aa)
NCF4Neutrophil cytosol factor 4. (352 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
HMOX1Heme oxygenase 1. (296 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (104 aa)
ATF4-2Cyclic AMP-dependent transcription factor ATF-4. (124 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
HMOX2Heme oxygenase 2. (408 aa)
CREBBPACREB-binding protein isoform A. (1756 aa)
DESI1Desumoylating isopeptidase 1. (169 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
SESN2LSestrin 2. (509 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
Y1Q_0018516Ig-like domain-containing protein. (208 aa)
NCOR1Nuclear receptor corepressor 1 isoform B. (2411 aa)
CUL3Cullin-3; Belongs to the cullin family. (768 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
Y1Q_0008616HSA domain-containing protein. (1301 aa)
Y1Q_0019034RPN1_C domain-containing protein. (356 aa)
CUNH19orf43Uncharacterized protein. (118 aa)
COX18Mitochondrial inner membrane protein COX18. (267 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (95 aa)
MTFP1Mitochondrial fission process protein 1. (167 aa)
KLHL17BTB domain-containing protein. (590 aa)
SPPL3Signal peptide peptidase-like 3. (384 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (463 aa)
COILCoilin. (612 aa)
COX11Cytochrome c oxidase assembly protein COX11, mitochondrial. (171 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (441 aa)
MAFKTranscription factor MafK. (188 aa)
COX19Cytochrome c oxidase assembly protein COX19. (94 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (413 aa)
TBL1XUncharacterized protein. (525 aa)
HELZ2Helicase with zinc finger domain 2. (2821 aa)
Y1Q_0005128Proteasome subunit beta. (277 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
P4HBProtein disulfide-isomerase. (512 aa)
PRDX5Peroxiredoxin-5, mitochondrial. (67 aa)
COX6CCytochrome c oxidase subunit 6C. (105 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (179 aa)
SKP2S-phase kinase-associated protein 2. (419 aa)
NOX4NADPH oxidase 4 isoform B. (628 aa)
KLHL18Kelch-like protein 18. (578 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (196 aa)
COX7A2Cytochrome c oxidase subunit 7A2, mitochondrial. (89 aa)
BACH2Transcription regulator protein BACH2. (605 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (152 aa)
COX14Cytochrome c oxidase assembly-like protein 14. (69 aa)
NPVFPro-FMRFamide-related neuropeptide VF. (159 aa)
Y1Q_0019264Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (129 aa)
NDUFA4Cytochrome c oxidase subunit NDUFA4. (82 aa)
AKT2Non-specific serine/threonine protein kinase. (270 aa)
TGS1-2Uncharacterized protein. (111 aa)
TGS1Trimethylguanosine synthase. (585 aa)
CCSCopper chaperone for superoxide dismutase. (277 aa)
GPX2Glutathione peroxidase 2. (155 aa)
BLVRBFlavin reductase (NADPH). (209 aa)
PSMB9Proteasome subunit beta. (216 aa)
PSMB8Proteasome subunit beta. (282 aa)
BTRCF-box/WD repeat-containing protein 1A isoform B. (626 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (348 aa)
UBXN7UBX domain-containing protein 7. (489 aa)
TXNRD3Glutaredoxin domain-containing protein. (604 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (355 aa)
HM13Minor histocompatibility antigen H13. (369 aa)
COX20Protein FAM36A isoform A. (181 aa)
AKT3-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
DESI2Desumoylating isopeptidase 2. (164 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
PSME4Proteasome activator complex subunit 4. (1808 aa)
TACO1Translational activator of cytochrome c oxidase 1. (358 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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