39 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (114 aa)
	KCNJ3	G protein-activated inward rectifier potassium channel 1. (497 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1017 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	GNB3	WD_REPEATS_REGION domain-containing protein. (340 aa)
	GPR156	Putative G-protein coupled receptor 156. (466 aa)
	KCNJ6	IRK_C domain-containing protein. (107 aa)
	KCNJ15	ATP-sensitive inward rectifier potassium channel 15. (407 aa)
	Y1Q_0011868	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (793 aa)
	Y1Q_0023975	Uncharacterized protein. (471 aa)
	KCNJ9	Uncharacterized protein. (415 aa)
	KCNJ10	ATP-sensitive inward rectifier potassium channel 10. (378 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1074 aa)
	GNAO1	Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
	ADCY6	Uncharacterized protein. (1272 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	KCNJ16	Inward rectifier potassium channel 16. (424 aa)
	KCNJ4	Inward rectifier potassium channel 4. (425 aa)
	KCNJ12	Uncharacterized protein. (429 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (228 aa)
	ADCY9	Adenylate cyclase type 9 isoform B; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (993 aa)
	ADCY2-2	Guanylate cyclase domain-containing protein. (226 aa)
	Y1Q_0015413	ANF_receptor domain-containing protein. (189 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2 isoform B. (804 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4 isoform A. (440 aa)
	KCNJ4-2	Uncharacterized protein. (457 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	Y1Q_0015615	Uncharacterized protein. (89 aa)
	KCNJ14	G protein-activated inward rectifier potassium channel 4-like. (609 aa)
	ADCY3-2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (119 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (155 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (344 aa)
	Y1Q_0014655	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1059 aa)
	Y1Q_0018299	Uncharacterized protein. (488 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (959 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	A0A151P235	A0A151PGT0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.449
ADCY1	ADCY2-2	A0A151P235	A0A151NCX3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein.	0.429
ADCY1	ADCY3	A0A151P235	A0A151M126	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.459
ADCY1	ADCY3-2	A0A151P235	A0A151P1B5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.948
ADCY1	ADCY6	A0A151P235	A0A151MUF3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.460
ADCY1	ADCY7	A0A151P235	A0A151MRZ2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.455
ADCY1	ADCY9	A0A151P235	A0A151N6G1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9 isoform B; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.674
ADCY1	GNAI3	A0A151P235	A0A151P6Y4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.951
ADCY1	GNAO1	A0A151P235	A0A151MSR7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(O) subunit alpha.	0.531
ADCY1	GNB3	A0A151P235	A0A151MCT7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	WD_REPEATS_REGION domain-containing protein.	0.816
ADCY1	GNB4	A0A151P235	A0A151M6J3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit beta-4.	0.825
ADCY1	GNG12	A0A151P235	A0A151NJB1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.807
ADCY1	GNG13	A0A151P235	A0A151N235	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.870
ADCY1	GNG2	A0A151P235	A0A151N3B0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.822
ADCY1	GNG3	A0A151P235	A0A151LZJ9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.836
ADCY1	GNG4	A0A151P235	A0A151M2U9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.822
ADCY1	GNG8	A0A151P235	A0A151P1V9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.527
ADCY1	PTRHD1	A0A151P235	A0A151P1V8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.509
ADCY1	Y1Q_0011868	A0A151P235	A0A151MHW5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.496
ADCY1	Y1Q_0014655	A0A151P235	A0A151P8F6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.606