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ETS1 | Protein C-ets-1 isoform B. (540 aa) | ||||
CHD8 | Uncharacterized protein. (2136 aa) | ||||
RUNX1 | Runt-related transcription factor. (398 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (753 aa) | ||||
KDM5B | Lysine-specific demethylase 5B isoform A. (1519 aa) | ||||
MYCN | N-myc proto-oncogene protein. (248 aa) | ||||
DDX17 | Putative ATP-dependent RNA helicase DDX17 isoform B; Belongs to the DEAD box helicase family. (605 aa) | ||||
MAFK | Transcription factor MafK. (188 aa) | ||||
RELA | Transcription factor p65. (350 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) | ||||
EOMES | Eomesodermin-like protein isoform B. (404 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (429 aa) | ||||
RUNX1-2 | Runt domain-containing protein. (486 aa) | ||||
SPI1 | Transcription factor PU.1. (266 aa) | ||||
TBP | TATA-box-binding protein. (301 aa) | ||||
OTX2 | Homeobox protein OTX2. (373 aa) | ||||
NFE2L2 | Nuclear factor erythroid 2-related factor 2. (482 aa) | ||||
NR1H3 | Oxysterols receptor LXR-alpha. (408 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (453 aa) | ||||
GATA6 | Transcription factor GATA-6. (325 aa) | ||||
KMT2D | Histone-lysine N-methyltransferase 2D isoform C. (4340 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein. (832 aa) | ||||
YAP1 | Transcriptional coactivator YAP1 isoform A. (432 aa) | ||||
PGR-1 | Progesterone receptor isoform B. (408 aa) | ||||
E2F1 | Transcription factor E2F1. (426 aa) | ||||
TRIM28 | Transcription intermediary factor 1-beta isoform C. (823 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein beta. (141 aa) | ||||
TAF1 | Transcription initiation factor TFIID subunit. (1966 aa) | ||||
GATA3 | Trans-acting T-cell-specific transcription factor GATA-3. (379 aa) | ||||
ZBTB33 | Transcriptional regulator Kaiso. (702 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa) | ||||
KMT2D-2 | Uncharacterized protein. (2572 aa) | ||||
CREBBP | CREB-binding protein isoform C. (2208 aa) |